1. Biosense Webster Israel

2. A Bit About Us Founded 1994 - Shlomo Ben-Haim, M.D. Acquired by J&J - 1997

3. A Bit About Us Our headquarters – Tirat HaCarmel

4. A Bit About Us Biosense Webster – about 700 employees worldwide About 100 employees in Israel (mostly R&D) Worldwide sales of about 300 million USD Profits of about 40 million USD Commands about 80% of the intracardiac navigation devices market

5. What Are We Doing It all began with an EP catheter …

6. EP Overview Inserting catheterReaching the heart Typical EP procedure consists of:

7. EP Overview Navigating inside the heart And …

8. However … The main (and only) instrument for knowing what’s going on inside the heart is fluoro.

9. However … In addition to emitting harmful radiation, it produces images that are hard to interpret

10. However … Especially when the heart is beating

11. Location Technology We place a number of transmitters under the patient table …

12. Location Technology … and a receiver in the catheter tip …

13. Location Technology … and triangulate our position!

14. Mapping Now we know the location of the catheter tip with respect to the table. So what? X = 11.34 Y = 533.89 Z = 45.78

15. Mapping We can map the heart from the inside and find the location of the catheter tip with respect to the map.

16. Mapping The map is also very useful in displaying electrical activity of the heart.

17. Mapping Still there is one problem left: heartbeat. We can either synchronize with ECG …

18. Mapping … or try to build a dynamic model of the heart

19. Questions So Far Any Questions?

20. What Else Are We Doing Remote Magnetic Navigation - Stereotaxis

21. What Else Are We Doing Stereotaxis: performing EP procedure

22. What Else Are We Doing Integration of pre-acquired images (MRI, CT, etc).

23. What Else Are We Doing Ultrasound catheter

24. What Else Are We Doing Different catheters (Quick, Flower, etc). Research versions Trying to analyze heart’s electrical activity New applications (neurosurgery, orthopedy, etc.) Etc, etc, etc.

25. And Last But Not Least … …

26. And Last But Not Least Biosense Webster Wants You! (well, maybe…)