1. Ecstasy (MDMA) Slang Terms XTC, Adam, E, Eve, History 1914 Merck for appetite suppressant 1970s Psycotherapy and Recreational Use 1985 DEA Schedule I 1996 number one recreational drug in Europe

2. Ecstasy (MDMA) Acute Toxicity Symptoms Complications Aggravating Factors Treatment Symptomatic Decrease body temp Hydration Control excitation and convulsions

4. Ecstasy (MDMA) Internet Information “How to make Acid” “MDMA and Penacillin” “MDMA in piss” “Herbal Ecstasy trial” “How to Get Ecstasy Samples Tested”

6. Gamma Hydroxybutyric Acid (GHB) Slang Terms Grievous Bodily Harm Georgia Home Boy Organic Quaalude Easy Lay Substitutes GBL - gamma butyrolactone 1,4 BD - butanediol

7. Gamma Hydroxybutyric Acid (GHB) History 1960- anesthetic effects but no analgesia 1977- GHB enhances growth hormone 1990- 57 cases of GHB-illness: banned from sale 1996- 69 cases reported in Texas/New York 1999 -2000 Federal law for use in rape, succesful homicide convictions in Michigan Possession legal, manufacture and sale not FDA approved use in narcolepsy trials

8. Gamma Hydroxybutyric Acid (GHB) Routes of Abuse Snorted or “Caps” Straight up or mixed in drinks GBL & BD GBL - Renewtrient - FDA\ask for voluntary ban BD - liquid (32oz) - Paris

9. Gamma Hydroxybutyric Acid (GHB) Internet Information Where and how to purchase GHB home manufacturing kits Case of “Hematuria from home- manufactured GHB” Latest cases involve recovering 1,4 BD from inkjet cleaner fluid “Hurricane”.

10. Gamma Hydroxybutyric Acid (GHB) Substitutes GHB, GBL, 1,4 BDL made C-I/C-III by Federal law 2000 Still most common product identified in forensic date-rape cases. Newest congener GVL – not as active pharmacologically

11. Gamma Hydroxybutyric Acid (GHB) 23 states have adopted Federal law. Only four states control for analogs 725 million pounds of 1,4 BD alone manufactured for industrial use a year

12. DEXTROMETHORPHAN Opiate derivative with NMDA\receptor activity Structure similar enough to PCP to react on urine drug screens Widely used in cough/cold products Available as an OTC chemical Slang names: “D”, “DXM”, “Vitamin D”, “Robo D”

13. DEXTROMETHROPHAN Internet information “Triple C” – Coricidin abuse” Purchase sites for bulk powder Chat rooms with How to make Robo Jello How to make Robo fruit rool-ups How to extract DM from syrups

17. Other news/new agents on the Web 2-CT-7 (hallucinogenic amphetamine) “Blue Mystic. Recommendations for SSRI’s and other prescription products for controlling adverse effects Ritalin and Adderall abuse recommendations “DNP” - Dinitrophenol (for weight loss) “Foxy methoxy” – 3 cases last week in Chicago

24. Major sites Erowid.org Lyceaum.org Dancesafe.com Drugfreeworkplace CDC.gov

25. Paloucek@uic.edu