1. METFORMIN
ZAINAB BAFFA

3. CONTENTS HYPOTHESIS BRIEF BACKROUND ON DIABETES MELLITUS
INTRODUCTION OF THE DRUG METFORMINE
CHEMICAL STRUCTURE
MECHANISM
SIDE EFFECTS OF METFORMINE
AIMS, SOLUTIONS AND ALTERNATIVES

4. HYPOTHESIS
Metfomin reduces the blood sugar level of people with type 2 diabetes.

5. TYPE 2 DIABETES

6. CHEMICAL STRUCTURE

7. MECHANISM It works in several ways;
it reduces the amount of sugar made by the liver,
limits the amount of sugar absorbed into the body from the diet, and makes insulin receptors more sensitive (helping the body respond better to its own insulin).
All of these effects cause a decrease in blood sugar levels.

9. SIDE EFFECTS
The most common adverse effect of metformin is gastrointestinal upset
Overdose: common symptoms include vomiting, diarrhea, abdominal pain, drowsiness, and, rarely hypoglycemia or hyperglycemia.
The major potentially life-threatening complication of metformin overdose is lactic acidosis, which is due to lactate accumulation. Lactic acidosis is a physiological condition characterized by low pH in body tissues and blood (acidosis) accompanied by the accumulation of lactate. The condition typically occurs when cells receive too little oxygen (hypoxia).

10. POSSIBLE SOLUTIONS, ALTERNATIVE
Before taking metformin, be sure that you don’t have any history of heart disease, liver failure .
Some of the metformin alternatives include:
Lifestyle changes
Other oral diabetes medications like Chlorpropamide, Glipizide.
Insulin .

11. REFERENCES
Pubmed.com
Drugs.com

12. THANK YOU