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Prevention of Surgical Site Infections (SSI) MSIPC Fundamentals of Infection Prevention & Control October 2014 Karen Hoover, RN Infection Prevention Coordinator.

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Presentation on theme: "Prevention of Surgical Site Infections (SSI) MSIPC Fundamentals of Infection Prevention & Control October 2014 Karen Hoover, RN Infection Prevention Coordinator."— Presentation transcript:

1 Prevention of Surgical Site Infections (SSI) MSIPC Fundamentals of Infection Prevention & Control October 2014 Karen Hoover, RN Infection Prevention Coordinator St. Mary’s of Michigan, Saginaw

2 SSI: A Complication of Surgical Care > 51.4 million surgical procedures/year in US 31% of all HAI’s due to SSI, second only to UTI > 91,000 readmissions for SSI Rx 1 million additional inpatient days 1.6 billion excess costs Associated mortality rate of 3% Cost… Pay for performance …patient safety CDC’s Guideline for Prevention of Surgical Site Infection, 1999.8 Jan 2014 CDC

3 Common surgical/Procedures 719,000/year Total knee 498,000 hysters 395,000 CABG 332,000 Total Hip Ambulatory 1.3 million cataracts 923,000 Lens implants 779,000 Endoscopies 735,000 Injections of spine Approx. 40% have more than 1 procedure CDC www.cdc.gov/nchs/data/nhsr/nhsr011.pdfwww.cdc.gov/nchs/data/nhsr/nhsr011.pdf

4 Risk Factors for SSI: identification & opportunities for intervention Risk factor: variable with significant, independent association with development of SSI Patient: age, nutrition, diabetes, smoking, obesity, immunocompromised, pre-op LOS, micro-flora, other infection SSI prevention measure: action(s) to reduce SSI risk, antibiotic prophylaxis, skin prep/antisepsis Operation: …patient & peri-op personnel, duration, antibiotic redosing,, surgical asepsis, traffic flow, surgical technique (robotic), hair removal, immediate use sterilization Environmental: cleaning, disinfectant contact time, UV light, OR environment-HVAC Risk of SSI after receipt of blood products 3.5%

5 Principles for Prevention of SSI Minimize access of bacteria to the surgical site Measures to neutralize that do gain access to site Reduce that which is conducive to infection Enhance the host defenses - look at risk factors Follow established guidelines

6 Pathogenesis of Surgical Site Infection (SSI) Dose x virulence Resistance of Host = risk of SSI > 10 5 / gm tissue  risk; with foreign body only 100/gm is needed to cause SSI Pathogens: Endogenous – flora normally contained Exogenous – healthcare personnel, environment, devices/materials used

7 Key Concepts on Source of SSI Pathogen: OR personnel or patient? Every surgical site has bacteria by the end of the procedure! Four Clinical variables determine infection: Inoculum of bacteria Virulence of bacteria Microenvironment Host defenses Endogenous – flora normally contained

8 Distribution of Pathogens Causing SSIs Mangram AJ. AJIC 1999;27:97-134

9 Risk Classification for SSI: CLASS I/CLEAN WOUNDS-- an uninfected surgical wound in which no inflammation is encountered and the respiratory, alimentary, genital, or uninfected urinary tracts are not entered. CLASS II/CLEAN-CONTAMINATED WOUNDS--a surgical wound in which the respiratory, alimentary, genital, or urinary tracts are entered under controlled conditions and without unusual contamination. CLASS III/CONTAMINATED WOUNDS--open, fresh, accidental wounds. In addition, surgical procedures in which a major break in sterile technique occurs (eg, open cardiac massage) or there is gross spillage from the gastrointestinal tract and incisions in which acute, nonpurulent inflammation is encountered are included in this category. http://findarticles.com/p/articles/mi_m0FSL/is_1_88/ai_n27912210 /

10 Smoking & Surgery: Bad combination Randomized, controlled trial: 48 smokers(S) vs 30 never smoked (NS) 228 wounds evaluated SSI rate 12% S vs 2 % in NS SSI rate significantly less for S if abstain for 4wks (27% vs.1.1%) Wound rupture: 12% S vs. 0% NS When to stop … 30 days? 2-6months? Sorensen LT. Ann Surg 2003;238:1-5

11 Preoperative Patient Shower with Antimicrobial Soap Bacterial counts on skin are 9-fold lower after shower - chlorhexidine CDC SSI Guidelines: Require patients to bathe with antiseptic on at least the night before their operation CHG cloth use night before & day of surgery

12 Intranasal Mupirocin & Prevention of SSI Orthopedic & cardiothoracic patients - significant reduction in SSI among treated 1-3 However these were retrospective & used historical controls Another randomized trial in ortho.surg found less S. aureus nasal carriage but no signif. Reduction in SSI rate 4 1. Kluytmans JAJW. ICHE 1996; 17:780-5. 2. Cimochowski GE. Ann Thorac Surg 2001;71:1572-9. 3. Wilcox MH. J Hosp Infect 2003; 54(3):196-201. 4. Kalmeijer MD. Clin Infect Dis 2002;35:353

13 Rate Per 100 CABGs Preventing Surgical Site Infection: System-level success [Usry GH, et al. AJIC 2002;30:434-6.] Intervention: Intranasal mupirocin 48 hrs prior to through 5 days post op Results: 94% of patients Rx Rate of SSI dropped by: 53% overall 55% for deep sternal

14 Surgical Care Improvement Project (SCIP) Antibiotic Timing - <60min Antibiotic Selection – type/body location of procedure - dosing for body wt. - duration of procedure - PCN allergy? - cost of antibiotic 2006 http://www.medscape.org/ viewarticle/531895_2http://www.medscape.org/ viewarticle/531895_2 Ancef Vancomycin or Clindamycin

15 Surgical Care Improvement Project (SCIP) within 24 hours surgery end time (SStop ATB 24 Hours end time 48 for Cardiac Surgery Blood sugar <200 at 6 am POD 1 & 2 S Controlled @ < 200 by 6STTTTTTGKLBLK a.m. POD 1 & 2 for Appropriate Hair removal …no razors DVT Prophylaxis Beta-blocker given before OR and after unless contraindicated DVTeICD ( Int. Compression Device), TED’s, Heparin, Warfarin Foley cath …remove by POD 2 or physician note why not

16 Centers for Medicare & Medicaid Services (CMS) Actions Payment reforms for inpatient hospital services in 2008 : …ensure that Medicare no longer pays for the additional costs of certain preventable conditions (including certain infections) acquired in the hospital… 1) Serious preventable events: Object left in during surgery; air embolism; Delivering ABO-incompatible blood or blood products 2) catheter-associated urinary tract infections 3) pressure ulcers 4) Vascular catheter associated infection 5) Mediastinitis after CABG surgery 6) Patient falls 7) VAE 8) Influenza vaccination rates 9) Future: MRSA, S. aureus BSI, CDAD (C. diff)

17 Impact of SSI Occurring After Discharge * Many/Most SSI not identified until after discharge Cost for care with SSI were 2.9 times greater 23% of readmits & 18% of ER visit …some at other facilities Post discharge SSIs can impair physical & mental health Surveillance (PDS) is inconsistent …phone/paper …honest Education - ? enough/consistent/updated Host defense – acute and chronic medical conditions Effective management to minimize consequences

18 Stitch/SuperficialDeep Pt.DOBSurgClassRoomProcedure DescriptionStapleIncisional 5/22/633/7 1 OR 12DECOMPRESSIVE LAMINECTOMY L4-5, L5-S1, NEURO FORAMOTOMY L4-5, L5-S1 4/8/543/7 1 OR 12KNEE ARTHROSCOPY LEFT 7/29/593/30 1 OR 12KNEE ARTHROSCOPY RIGHT, PARTIAL MENISCECTOMY, 6/20/623/14 1 OR 12KNEE ARTHROSCOPY LEFT, PARTIAL MENISECTOMY, PARTIAL CHONDROPLASTY 11/19/683/21 1 OR 12KNEE ARTHROSCOPY RIGHT, PARTIAL CHONDROPLASTY, RELEASE PLICA 1/28/323/28 1 OR 12KNEE TOTAL ARTHROPLASTY LEFT 8/31/913/28 1 OR 12left KNEE ARTHROSCOPY with fixation of osteochondyle fx, debridement of 8/18/403/21 1 OR 12LEFT TOTAL HIP REPLACEMENT 9/10/303/11 1 OR 10OPEN REDUCTION, PINNING RIGHT FEMORAL NECK 1/29/053/15 1 OR 8REALINEMENT WITH PINNING AND CASTING LEFT ELBOW 9/16/603/14 1 OR 12RELEASE OF ACHILLES TENDON RIGHT 2/24/323/7 1 OR 12REMOVAL OF FOREIGN BODY RIGHT THIGH ANTIBIOTIC BEADS 5/14/593/30 1 OR 12REVISION LEFT TOTAL KNEE ARTHROPLASTY, EXTENSIVE SYNOVECTOMY 11/1/443/28 1 OR 12REVISION, POLY LEFT KNEE, DEBRIDMENT, LATERAL RELEASE 1/13/253/21 1 OR 12RIGHT KNEE ARTHROSCOPY, CHONDROPLASTY, PARTIAL MENISCECTOMY 12/1/383/28 1 OR 12RIGHT OPEN QUADRICEPS REPAIR WITH AFLEX GRAFT Stitch/staple: minimal inflammation and discharge confined to the points of suture penetration Superficial Incisional:Purlent drainage from the superficial incision; or pain or tenderness, localized swelling, redness, or heat, and superficial incision is deliberately opened by surgeon, and is culture-positive or not cultured If from secondary incison (e.g., donor site [leg] incision for CABG), please note: Y- SIS Deep incisional :a. purulent drainage from the deep incision but not from the organ/space b. incision spontaneously dehisces or is deliberately opened by a surgeon and is culture-positive or not cultured a. purulent drainage from the deep incision but not from the organ/space during reoperation, or by histopathologic or radiologic examination. ICD – 9 – CM codes

19 The Challenge of Surveillance of SSIs: expanding universe of health care delivery Major trend towards delivery in wide range of settings Short lengths of stay + inter- facility transfer is common Networking!

20 Ambulatory Surgery: Risk Free? Cluster of fungal contamination of saline breast implant Saline bottle stored under water-damaged ceiling & OR in negative pressure Kainer MA. 40th IDSA (abstr) Cluster of Endoph-thalmitis after cataract surg. Acremonium kiliense 4 patients Risk Factor (RF): 1st case, Mondays Humidified air in ventilation likely source Fridkin SK. Clin Infect Dis 1996; Steroid Injection Outbreak

21 CMS for Ambulatory Care 42 CFR Part 416 Medicare and Medicaid Programs; Ambulatory Surgical Centers (ASC), Conditions for Coverage: …require the ASC to designate a qualified professional, such as a registered nurse, as the infection control officer The infection control condition places accountability on ASCs to prevent, control, and investigate infections and communicable diseases, and take action that result in improvements…

22 Waterless Alcohol-based Hand Rub for Surgical Hand Antisepsis Randomized trial, 4387 pts. Hand rub vs scrub with antimicrobial soap + water SSI rate in hand rub (2.4%) vs scrub (2.5%) not signif. Better compliance, less skin irritation/dryness with hand rub in personnel WHO Parienti JJ. JAMA 2002; 288:722-77

23 Possible SSI Prevention Measures Subcuticular suturing vs skin stapling technique, CABG - 2 studies; no consistent results (Mullen JC. Can J Cardiol 1999;15:65- ; Chughtai T. Can J Cardiol 2000;16:1403-) Quill Suturing? …expensive Anemia & leukocyte-depleted red blood cell transfusion - studies have had mixed results; more study needed (Jensen LS. Transfusion 1995;35:719-; Titlestad IL. Int J Colorectal Dis 2001;16:147-;van de Watering LM. Circulation 1998;97:562-) Laminar Airflow & Orthopedic Surgery - Mixed results & difficult to demonstrate clear cost effectiveness (Berbari EF. Clin Infect Dis 1998;27:1247-)

24 Possible SSI Prevention Measures Supplemental perioperative oxygen- randomized trial found lower SSI with 80% O2 among 500 colorectal surgery pts.;however-high SSI rate & risk index in control population - Need confirmation (G rief R. N Engl J Med 2000;342:161-7) Periop. normothermia - randomized trial of 200 patients, colorectal surgery pts. = lower SSI rate with additional warming(forced air + IV fluids) vs those with regular care; more investigation needed for wider application (Kurz A. N Engl J Med 1996;334:1209-15)

25 Category IA SSI Prevention Recommendations Patient-focus: treat existing infections first before OR avoid hair removal but if needed use clippers Asepsis & technique: aseptic principles: IV, inserting catheters, administering medications AJIC 1999;27:97-132

26 Category IB SSI Prevention Recommendations Patient-focus: control serum blood glucose encourage tobacco cessation preop shower clean skin incision site + apply antiseptics Surgical Team: no artificial nails surgical hand antisepsis AJIC 1999;27:97-132

27 Category IB SSI Prevention Recommendations Intraoperative: Positive pressure in OR Min. 15 air changes/hour Filter supply air Keep OR doors closed as much as possible sterilize surgical instruments; limit flash sterilization Surgical Team: surgical mask, hair cover gown & sterile gloves Gentle handling of tissue AJIC 1999;27:97-132

28 Category IB SSI Prevention Recommendations Surveillance: Use CDC definitions Apply risk index Periodically calculate risk stratified SSI rates Report SSI rates to surgical personnel Use standard case finding methods AJIC 1999;27:97-132

29 Surgical Site Infection Criteria Superficial incisional SSI Infection occurs within 30 days after any NHSN operative procedure and involves only skin and subcutaneous tissue of the incision and patient has at least one of the following: a. purulent drainage from the superficial incision. b. organisms isolated from an aseptically-obtained culture of fluid or tissue from the superficial incision. c. superficial incision that is deliberately opened by a surgeon and is culture-positive or not cultured and patient has at least one of the following signs or symptoms: pain or tenderness; localized swelling; redness; or heat. A culture negative finding does not meet this criterion. d. diagnosis of a superficial incisional SSI by the surgeon or attending physician or other designee (see reporting instructions).

30 Two specific types of superficial incisional SSIs Superficial Incisional Primary (SIP) superficial incisional SSI that is identified in the primary incision in a patient that has had an operation with one or more incisions (e.g., C-section incision or chest incision for CABG) Superficial Incisional Secondary (SIS) superficial incisional SSI that is identified in the secondary incision in a patient that has had an operation with more than one incision (e.g., donor site incision for CBGB) Do not report a stitch abscess, stab wound or pin site infection as SSI Diagnosis of “cellulitis”, by itself, does not meet criterion d for superficial incisional SSI.

31 Deep incisional SSI Infection occurs within 30 or 90 days after the NHSN operative procedure and involves deep soft tissues of the incision (e.g., fascial and muscle layers) and patient has at least one of the following: a. purulent drainage from the deep incision. b. a deep incision that spontaneously dehisces or is deliberately opened by a surgeon and is culture-positive or not cultured and patient has at least one of the following S/S: fever (>38°C); localized pain or tenderness. c. an abscess or other evidence of infection involving the deep incision d. diagnosis of a deep incisional SSI by a surgeon or attending physician or other designee

32 Organ/Space SSI Infection occurs within 30 or 90 days after the NHSN operative procedure and infection involves any part of the body, excluding the skin incision, fascia, or muscle layers, that is opened or manipulated during the operative procedure and patient has at least one of the following: a. purulent drainage from a drain that is placed into the organ/space b. organisms isolated from an aseptically-obtained culture of fluid or tissue in the organ/space c. an abscess or other evidence of infection involving the organ/space

33 Special Comments: Occasionally an organ/space infection drains through the incision and is considered a complication of the incision. Therefore, classify it as a deep incisional SSI. Report mediastinitis following cardiac surgery that is accompanied byosteomyelitis as SSI-MED rather than SSI-BONE. If meningitis (MEN) and a brain abscess (IC) are present together after operation, report as SSI-IC. Report CSF shunt infection as SSI-MEN if it occurs within 90 days of placement; if later or after manipulation/access, it is considered CNS-MEN Report spinal abscess with meningitis as SSI-MEN following spinal surgery.

34 Environmental Infection Control Guidelines, 2003 HVAC: Positive pressure ventilation Filtration Environmental Cleaning Preventing water-associated illness Preventive maintenance MMWR 2003;52:RR-10

35 A Surgeon’s Perspective on Prevention of SSI “ The most critical factors in the prevention of postoperative infections, although difficult to quantify, are the sound judgment and proper technique of the surgeon and surgical team, as well as the general health and disease state of the patient” -Nichols RL. Emerg Infect Dis 2001;7(No.2):220-4.

36 How to Display SSI data: Target …state in IP Plan Just %? …what if 1 of 2 procedures develop SSI? Denominator & numerator? Graphs Previous year …2 years? Scorecards Compare with NNIS vs Standard Infection Ratio (SIR) Special Investigations High volume surgery Surgeon specific? “Tell them/show them what they need to see”

37 Sample of displaying SSI’s CABG 1 1 13111 # done17824131513191415251714194161116 SSI rate/month7.7%5.3%7.1%1.5%6.3%9.1%6.3% Cardiac other 1 11 3 # done73536438424352283 SSI rate/month33.3%12.5%25.0%5.8% Colon212 11 1 2 10 1 # done1079116 12181225151214811 17 SSI rate/month20.0%14.3%22.2%16.7%9.1%5.6%8.0%6.8%5.9% Last Updated 9/17/2010, 11/1/2010, 1/17/2011

38 Post discharge Data Surveillance: Patient Name DOB Surgery Class Room Procedure Description Name of hospital _________________ Education: New surgeons/Annually (definitions) Skin/staple related? …don’t count Incisional … skin or sub-Q, drainage, dehisence, I&D Any cultures? Readmit? Within 30 days vs NEW 2013: 90 days (implants)

39 SSI Surveillance & Prevention Intervention Feedback: surgeon/surgical personnel or committee (s) Result: Overall SSI rate/SIR for given (targeted) surgeries Action Plan: Quality Improvement – education, equipment, timing, etc.

40 Summary Aspects of Surveillance Program for Prevention of SSIs SSIs cause considerable morbidity and mortality and are expensive complications to treat - prevention therefore is cost effective Surveillance & Interventional Epidemiology is an effective component of a facility’s patient safety/performance improvement program Feedback of process & outcome data is helpful but broad partnership involving multiple disciplines is likely key to success

41 Skin & Soft Tissue Infections Changing Pattern of Community- Associated Skin and Soft-Tissue Infection with methicillin-Resistant Staphylococcus aureus (CA-MRSA) Almost three quarters of the soft-tissue infections were caused by CA-MRSA (N=389 patients) King MD, et al. Ann Intern Med 2006; 144:309-317.

42 Conclusions: SSI’s will always be with us MDRO’s will challenge us New techniques and technology will evolve Government agencies will change how we measure quality performance Reimbursement can effect our process, advancing to new equipment or products, how we stay in business Do you know what and how to collect data?

43 Sterile Processing From Acquisition to Reuse

44 Sterilization of Equipment Certified technicians Cleaning …ultrasonic (5 to 10 min) open instruments …DRY/inspect Wrapping … trays

45 Sterilization - Steam 121 o C (250 o F) and 132 o C (270 o F). Manufacturers recommendation. Bowie-Dick test is used to detect air leaks and inadequate air removal Biological monitor: Geobacillus stearothermophilus (formerly Bacillus stearothermophilus) Monitored using a printout (or graphically) by measuring temperature, the time at the temperature, and pressure - Sterrad -Portable (table-top) steam sterilizers - Immediate use www.roboz.com/catalog%20pdfs/Sterilization_and_Maintenance.pdf quick chart www.roboz.com/catalog%20pdfs/Sterilization_and_Maintenance.pdf www.cdc.gov/hicpac/Disinfection_Sterilization/13_0Sterilization.html

46 Correct loading /unloading Sufficient space must occur around the packages place items on edge and no chamber wall touching do not stack packages or cassettes one upon the other paper of one pouch next to the plastic of the adjacent pouch Basins, bowls or other devices on their sides running a load with both linens and medical instruments, place the linen packs on the top shelf heavy medical items or large trays flat on the bottom shelves Some steam sterilizers have an automatic dry cycle opening the door about ½ inch after the pressure equalizes and let items sit inside the chamber for 30 to 60 minutes Wet packages that exist at the end of steam-sterilization cycles should not be handled

47 Steam Sterilizer recall Recalls due mechanical, chemical and biological -Who you going to call? Retrieval of processed items Notify your sterilizer service representative Re-validated with three consecutive negative biological monitors in three consecutive cycles AAMI recommends that sterilizers be biologically monitored at least once a week, preferably daily, when normal cycles are used, in each flash sterilization load and in any load containing an implantable device. http://www.spdceus.com/recalls.htm for online info & quiz http://www.spdceus.com/recalls.htm


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