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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Chapter 16: The Lymphatic System and Lymphoid Tissue.

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Presentation on theme: "Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Chapter 16: The Lymphatic System and Lymphoid Tissue."— Presentation transcript:

1 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Chapter 16: The Lymphatic System and Lymphoid Tissue

2 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Overview

3 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Key Terms adenoidlymphadenopathylymphoma chylelymphangitisspleen lymphlymphatic ductthymus lymphadenitislymph nodetonsil

4 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease The Lymphatic System System of tissues and vessels Scattered throughout the body Services almost all regions

5 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Functions of the Lymphatic System Learning Outcome 1.List the functions of the lymphatic system.

6 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Functions of the Lymphatic System Three Main Functions Fluid balance (lymph) Protection from infection Absorption of fats

7 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Functions of the Lymphatic System ✓ Checkpoint 16-1What are the three functions of the lymphatic system?

8 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Lymphatic Circulation Learning Outcomes 2.Explain how lymphatic capillaries differ from blood capillaries. 3.Name the two main lymphatic ducts and describe the area drained by each.

9 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Lymphatic Circulation One-way system Begins in tissues Ends in bloodstream

10 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Figure 16-1 The lymphatic system in relation to the cardiovascular system. What type of blood vessel receives lymph collected from the body?

11 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Lymphatic Circulation Lymphatic Capillaries Capillary walls (endothelium) are flattened epithelial cells. They are more permeable than blood capillaries. Overlapping cells form one-way valves. They arise blindly (closed at one end). Lacteals absorb digested fats.

12 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Figure 16-2 Lymphatic drainage in the tissues.

13 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Lymphatic Circulation Lymphatic Vessels Superficial and deep sets Right lymphatic duct Thoracic duct (left lymphatic duct) –Cisterna chyli

14 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Figure 16-3 Vessels and nodes of the lymphatic system. What are some nodes that receive lymph drainage from the breast?

15 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Lymphatic Circulation Movement of Lymph Movement of lymph toward heart caused by: –Valves in lymphatic vessels –Contraction of lymphatic vessels –Skeletal muscle contraction –Breathing

16 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease

17 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Lymphatic Circulation ✓ Checkpoints 16-2What are the two differences between blood capillaries and lymphatic capillaries? 16-3What are the two main lymphatic vessels?

18 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Lymphatic Circulation ? Pop Quiz 16.1 Which of the following is NOT characteristic of lymphatic vessels? A) They have thin walls. B) They are blind-ended. C) They can contract to propel lymph. D) They transport lymph to the tissues.

19 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Lymphatic Circulation ? Pop Quiz Answer 16.1 Which of the following is NOT characteristic of lymphatic vessels? A) They have thin walls. B) They are blind-ended. C) They can contract to propel lymph. D) They transport lymph to the tissues.

20 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Lymphoid Tissue Learning Outcome 4.List the major structures of the lymphatic system and give the locations and functions of each.

21 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Lymphoid Tissue Distributed throughout the body Makes up specialized organs of lymphatic system

22 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Figure 16-5 Location of lymphoid tissue.

23 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Lymphoid Tissue Lymph Nodes Cervical nodes Axillary nodes Tracheobronchial Mesenteric nodes Inguinal nodes

24 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Figure 16-3 Vessels and nodes of the lymphatic system. What are some nodes that receive lymph drainage from the breast?

25 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Figure 16-4 Lymph nodes. What type of lymphatic vessel carries lymph into a node? What type of lymphatic vessel carries lymph out of a node?

26 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Lymphoid Tissue The Spleen Cleanses blood –Filtration –Phagocytosis Destroys old red blood cells Produces red blood cells before birth Is a reservoir for blood

27 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Lymphoid Tissue The Thymus Plays a key role in early immune system development Produces thymosin –Develops T-lymphocyte cells –Promotes lymphocyte growth –Promotes lymphoid tissue activity Shrinks after puberty

28 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Lymphoid Tissue The Tonsils Remove contaminants and trap pathogens Palatine tonsils Pharyngeal tonsil (adenoids) Lingual tonsils Surgery to treat if recurrent infection or enlarged tonsils make swallowing or breathing difficult

29 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Figure 16-6 Location of the tonsils.

30 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Lymphoid Tissue Other Lymphoid Tissue Appendix Mucosal-associated lymphoid tissue (MALT) Gut-associated lymphoid tissue (GALT)

31 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease

32 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Lymphoid Tissue ✓ Checkpoints 16-4What is the function of the lymph nodes? 16-5What is filtered by the spleen? 16-6What kind of immune system cells develop in the thymus? 16-7What is the general location of the tonsils?

33 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Lymphoid Tissue ? Pop Quiz 16.2 Lymph from the arm and breast passes through which of the following? A) Inguinal nodes B) Cervical nodes C) Axillary nodes D) Tracheobronchial nodes

34 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Lymphoid Tissue ? Pop Quiz Answer 16.2 Lymph from the arm and breast passes through which of the following? A) Inguinal nodes B) Cervical nodes C) Axillary nodes D) Tracheobronchial nodes

35 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Disorders of the Lymphatic System Learning Outcome 5.Describe the major lymphatic system disorders.

36 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Disorders of the Lymphatic System and Lymphoid Tissue Disorders Related to Infection ●Lymphadenopathy ●Lymphadenitis ●Infectious mononucleosis Lymphedema ●Elephantiasis

37 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Figure 16-7 Infectious mononucleosis.

38 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Figure 16-8 Lymphangitis.

39 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease

40 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Disorders of the Lymphatic System and Lymphoid Tissue Splenomegaly Lymphoma –Hodgkin lymphoma –Non-Hodgkin lymphoma

41 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Figure 16-9 Reed-Sternberg cell.

42 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Disorders of the Lymphatic System and Lymphoid Tissue ✓ Checkpoints 16-8What is lymphadenopathy? 16-9What is lymphoma and what are the two examples of malignant lymphoma?

43 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Disorders of the Lymphatic System and Lymphoid Tissue ? Pop Quiz 16.3 What is Hodgkin lymphoma? A) A benign tumor of the lymph nodes B) A malignant tumor of the lymph nodes C) A benign tumor of the spleen D) A malignant tumor of the spleen

44 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Disorders of the Lymphatic System and Lymphoid Tissue ? Pop Quiz Answer 16.3 What is Hodgkin lymphoma? A) A benign tumor of the lymph nodes B) A malignant tumor of the lymph nodes C) A benign tumor of the spleen D) A malignant tumor of the spleen

45 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Case Study Learning Outcome 6. Describe the spleen’s functions and the consequences of its removal.

46 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Case Study Functions of the Spleen Filters blood Removes worn-out old blood cells Acts as a large lymph node, detecting and fighting disease-causing organisms Consequences of Splenectomy Liver will take over blood filtration and RBC removal Greater risk of infection

47 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Word Anatomy Learning Outcome 7.Show how word parts are used to build words related to the lymphatic system.

48 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Word Anatomy

49 Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease


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