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Hepatitis C By rebecca baron.

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1 Hepatitis C By rebecca baron

2 What is it? Hepatitis C is a disease caused by a virus that infects the liver

3 Symptoms Most people have no symptoms when they are first infected
For that reason, from the million Americans living with viral HCV, as many as 75% are unaware that they are infected.

4 Symptoms Fatigue Belly pain Fever Itchy skin Nausea or poor appetite
Sore muscles Dark urine Tenderness of area around the liver Yellowish eyes and skin (jaundice) Joint pain

5 Symptom checker (1) Fever Fatigue Sore muscles Yellowing eyes and skin Tender Liver area Abdominal pain Itchy skin Dark Urine Joint pain The patient will click on the symptoms that apply and the words will turn red. This will allow the patient to track symptoms on a daily basis, or even to see the effects that Hep C has on his/her life at the beginning of the treatment.

6 Symptom checker (2) Itchy Skin Sore Muscles Stomach pain Jaundice
Joint pain Dark Urine Tiredness Another option is to have the pictures in a tile setting with a box for the patient to check off his or her symptoms. These symptoms will then be registered in the database. Symptom checker (2)

7 How is it spread? Spread from person to person when the blood of someone infected with the virus mixes with the blood of someone else

8 Causes Blood transfusions and organ transplants before 1992
Shared needles Childbirth Sexual contact

9 Risk factors Risk factors do not mean that you have Hepatitis C, but do indicate a greater risk of infection If you have one or more of the symptoms, you should get tested

10 Donated blood Before 1992, donated blood products and blood could not be tested for Hepatitis C Some people where accidentally infected after surgeries and other medical procedures

11 Baby boomers Born Could’ve been exposed to HCV when infection rates were higher in 70s and 80s

12 Drug use Infected by sharing tools to take drugs
Previously used: needles, syringes, cotton, water, or cocaine straws

13 Sex Rough, or anal sex without a condom
Any activity with blood to blood contact is a risk factor

14 Tools Sharing tattoo, piercing, or acupuncture needles
Manicure and pedicure tools Those working in a medical setting may be cut and exposed to the virus Must be cleaned and disinfected

15 Others Received hemodialysis treatments for a long period of time
Received clotting factor concentrates before 1987 Have HIV

16 Causes

17 Sometimes, the body clears the virus on its own
If it cannot, it will go into the Chronic phase of infection A serious condition that can lead to cirrhosis or liver cancer

18 Complications Scarring of the liver tissue (cirrhosis) Liver Cancer
After years of Hep C infection Liver Cancer Liver Failure

19 The liver

20 Functions of the liver Manufacturing blood proteins that aid in clotting, oxygen transport, and immune system function Storing excess nutrients and returning some of the nutrients to the bloodstream Manufacturing bile, a substance needed to help digest food

21 Helping the body store sugar (glucose) in the form of glycogen
Ridding the body of harmful substances in the bloodstream, including drugs and alcohol Breaking down saturated fat and producing cholesterol

22 What is cirrhosis? A slowly progressing disease in which healthy liver tissue is replaced with scar tissue, eventually preventing the liver from functioning properly

23 Implications The scar tissue blocks the flow of blood through the liver and slows the processing of nutrients, hormones, drugs, and naturally produced toxins

24 Comparison

25 Healthy liver vs liver with cirrhosis

26 Symptoms of cirrhosis Red palms due to expanded vessels
Spider veins near the chest, shoulders, and face Swelling of the belly, legs, and feet Shrinking of the muscles Bleeding from enlarged veins in your digestive system

27 Cirrhosis symptoms

28 Swollen and itchy hands

29 Swelling in the abdomen

30

31 Liver cancer Cancer that begins in the cells of the liver
One of the most common forms of cancer in the world

32 Liver cancer

33 Symptoms Weight loss Loss of appetite Upper abdominal pain
Nausea and vomiting General weakness and fatigue An enlarged liver Abdominal swelling Jaundice White, chalky stools

34 Liver cancer symptoms

35 Liver failure Occurs when large parts of the liver become damaged beyond repair and the liver is no longer able to function life-threatening

36 How can hcV be diagnosed?
Blood tests help to: Determine whether you have HCV Measure the quantity of HepC in your blood (viral load) Evaluate the genetic makeup of the virus (genotyping), which helps determine treatment options

37 A liver biopsy can help determine the severity of the disease and guide treatment decisions.
During the biopsy, a needle is injected through your skin, into your liver, and a tissue sample is removed.

38 No treatment for acute HCV
Treatment isn’t always necessary if you only have slight liver abnormalities, you may not need treatment, because your risk of future liver problems is very low.

39 Treatment for Chronic HCV
Combination antiviral therapy Liver transplant Vaccinations to protect against other forms of viral hepatitis

40 Antiviral medications
Peginterferon and ribivirin are combined to give the best response to treatment. A protease inhibitor (such as boceprevir or telaprevir) may be given alongside these meidcations.

41 Peginterferon is given as a shot once a week.
Ribavirin is taken as a pill 2 times a day.

42 APP: Treatment scrolling
Treatment Option For the treatments, I would like to have a rotating wheel where the patient can click on the option they prefer, then see the procedure, length of treatment, side effects, etc. With this option, the patient can navigate from left to right to find the best solution for him/her. However, the app recommendation will be highlighted in green.

43 The length of the treatment depends on what hepatitis C genotype you have.
Genotype 1: 1 year Genotype 2/3: 6 months

44 Liver transplant The surgeon removes your damaged liver and replaces it with a healthy liver Most transplants come from deceased donors This is not a cure Antiviral treatment often follows

45 Lifestyle remedies Stop drinking alcohol
Avoid medications that cause liver damage Stay healthy Help prevent others from coming in contact with your blood

46 Milk thistle: alternative medicine
May treat jaundice and other liver disorders Taken as a capsule, extract, or infusion

47 Video l_kw8qHGTI


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