Presentation on theme: "Hemophilia B. World Federation of Hemophilia Global Survey 2008 Demographics Number of countries in this survey: 108 Percentage of world population covered."— Presentation transcript:
World Federation of Hemophilia Global Survey 2008 Demographics Number of countries in this survey: 108 Percentage of world population covered by 2008 survey report: 91% Number of people identified with hemophilia A and B: 148,971 Number of people identified with VWD: 52,330 Number of people identified with other bleeding disorders: 21,510 Total number of people with bleeding disorders identified: 219,699
Prevalence in the Philippines 2008 PopulationNumber of People with Hemophilia Number of people with von Willebrand Disease Number of people with Other Bleeding disorder 97,976,60398428n/a Hemophilia A TotalHemophilia B TotalHemophilia type unknown Total vWD Total 8531314228
Early in life Bleeding after circumcision or rarely as intracranial hemorrhages Severe and moderate forms Hemarthroses Bleeding episodes into soft tissues & muscles after minor trauma or even spontaneously Harrison’s Principles of Internal Medicine, 17 th ed.
Clinical Features Severe forms Recurrent hemarthroses – most common bleeding manifestation – can affect every joint but mainly affect knees, elbows, ankles, shoulders, & hips Acute hemarthroses - painful, local swelling and erythema Chronic hemarthroses - debilitating, with synovial thickening & synovitis Harrison’s Principles of Internal Medicine, 17 th ed.
Clinical Features Mild forms Infrequent bleeding usually secondary to trauma Other manifestations Bleeding into oropharyngeal spaces, central nervous system, or retroperitoneum - requires immediate therapy Hematuria - self-limited Harrison’s Principles of Internal Medicine, 17th ed.