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The hypothalamo-hypophyseal systems. The pituitary gland.

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Presentation on theme: "The hypothalamo-hypophyseal systems. The pituitary gland."— Presentation transcript:

1 The hypothalamo-hypophyseal systems. The pituitary gland

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5 Regulation of endocrine organs Közp. idegr. Releasing hormon (pl. CRF) Adenohypophysis sejt (pl. corticotrop) Glandotrop hormon (pl. ACTH) Neurosecretion: secreration of neruon gets into the bloodstream Negative feedback: hormons of target organ inhibit the adenohypophysis

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7 - Median eminence Pituitary gland: parts

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9 Embryology: Rathke’s pouch + floor of diencephalon Problem: craniopharyngioma tumors

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11 Acidophil: GH, PROL

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14 Secreted hormoneAbbreviationProduced byEffect Oxytocin Magnocellular neurosecretory cells Uterine contraction Lactation (letdown reflex) Vasopressin Vasopressin (antidiuretic hormone) ADH Magnocellular neurosecretory neurons Increase in the permeability to water of the cells of distal tubule and collecting duct in the kidney and thus allows water reabsorption and excretion of concentrated urinedistal tubulecollecting duct

15 Portal circulation

16 Secreted hormoneAbbreviationProduced byEffect Thyrotropin-releasing hormone TRH, TRF, or PRH Parvocellular neurosecretory neurons Stimulate thyroid-stimulating hormone (TSH) release from anterior pituitary (primarily)thyroid-stimulating hormone (TSH) anterior pituitary Dopamine Dopamine (Prolactin-inhibiting hormone) DA or PIH arcuate nucleus Inhibit prolactin release from anterior pituitaryprolactinanterior pituitary Growth hormone-releasing hormone GHRH Arcuate nucleus Stimulate Growth hormone (GH) release from anterior pituitaryGrowth hormone (GH)anterior pituitary Somatostatin Somatostatin (growth hormone-inhibiting hormone) SS, GHIH, or SRIF Periventricular nucleus Inhibit Growth hormone (GH) release from anterior pituitary Inhibit thyroid-stimulating hormone (TSH) release from anterior pituitaryGrowth hormone (GH)anterior pituitarythyroid-stimulating hormone (TSH)anterior pituitary Gonadotropin-releasing hormone GnRH or LHRH Preoptic area Stimulate follicle-stimulating hormone (FSH) release from anterior pituitary Stimulate luteinizing hormone (LH) release from anterior pituitaryfollicle-stimulating hormone (FSH) anterior pituitaryluteinizing hormone (LH)anterior pituitary Corticotropin-releasing hormone CRH or CRF Parvocellular neurosecretory neurons Stimulate adrenocorticotropic hormone (ACTH) release from anterior pituitaryadrenocorticotropic hormone (ACTH) anterior pituitary

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19 (1)Chromophils Acidophils - Somatotrophs - Mammotrophs Basophils - Thyrotrophs - Corticotrophs - Gonadotrophs (2)Chromophobes

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23 Herring bodies (Gömöri / chrome haematoxylin phloxine)

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25 3.: Bitemporal hemianposia

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