Presentation is loading. Please wait.

Presentation is loading. Please wait.

Deficiency in myeloid-resident NRP1 affects systemic metabolism.

Published byせいごろう のえ Modified over 5 years ago

Similar presentations

Presentation on theme: "Deficiency in myeloid-resident NRP1 affects systemic metabolism."— Presentation transcript:

1 Deficiency in myeloid-resident NRP1 affects systemic metabolism.
Deficiency in myeloid-resident NRP1 affects systemic metabolism. Daily food intake (A) and total beam breaks (B) of control and LysM-Cre-Nrp1fl/fl mice after 18 weeks on a regular diet. Daily food intake (C) and total beam breaks (D) of control and LysM-Cre-Nrp1fl/fl of 18-week-old mice after 10 weeks on HFD. VO2 (E), heat production (F), and RER (G) of control and LysM-Cre-Nrp1fl/fl mice 18 weeks on a regular diet. VO2 (H), heat production (I), and RER (J) of control and LysM-Cre-Nrp1fl/fl of 18-week-old mice after 10 weeks on HFD. Data are means ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001, Student’s unpaired t test (A and C) and two-way ANOVA with Bonferroni post hoc test (B and D to J) (n = 24, four mice per group). All graph points represent an average calculated over 7 days of measurements. Ariel Molly Wilson et al. Sci. Immunol. 2018;3:eaan4626 Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works

Download ppt "Deficiency in myeloid-resident NRP1 affects systemic metabolism."

Similar presentations

Identification of combination treatment–responsive dysfunctional tumor-infiltrating CD8+ T cell population. Identification of combination treatment–responsive.

Identification of combination treatment–responsive dysfunctional tumor-infiltrating CD8+ T cell population. Identification of combination treatment–responsive.
Fibroblast activation in WT and NFATc2-deficient mice.

Fibroblast activation in WT and NFATc2-deficient mice.
Pathogenic potential of naïve Helicobacter-reactive CT6 cells in lymphopenic mice. Pathogenic potential of naïve Helicobacter-reactive CT6 cells in lymphopenic.

Pathogenic potential of naïve Helicobacter-reactive CT6 cells in lymphopenic mice. Pathogenic potential of naïve Helicobacter-reactive CT6 cells in lymphopenic.
FIP200 deficiency alters mitochondria activation and ROS production in T cells. FIP200 deficiency alters mitochondria activation and ROS production in.

FIP200 deficiency alters mitochondria activation and ROS production in T cells. FIP200 deficiency alters mitochondria activation and ROS production in.
Basic design concept of human mimetic humanoid.

Basic design concept of human mimetic humanoid.
CD8α+ DC-deficient mice are highly susceptible to Lm infection in the absence of CD169+ macrophages. CD8α+ DC-deficient mice are highly susceptible to.

CD8α+ DC-deficient mice are highly susceptible to Lm infection in the absence of CD169+ macrophages. CD8α+ DC-deficient mice are highly susceptible to.
TPAD controller schematic and testing for WPC.

TPAD controller schematic and testing for WPC.
TPAD controller performance for three force components.

TPAD controller performance for three force components.
Three different types of transfer functions with a codomain of [0,1].

Three different types of transfer functions with a codomain of [0,1].
TPAD training protocol.

TPAD training protocol.
Tfr cells’ transcriptomic profile distinguishes them from Treg and Tfh cells. Tfr cells’ transcriptomic profile distinguishes them from Treg and Tfh cells.

Tfr cells’ transcriptomic profile distinguishes them from Treg and Tfh cells. Tfr cells’ transcriptomic profile distinguishes them from Treg and Tfh cells.
Regulatory CD4+ T cell–derived IL-10 is important for B cell differentiation and the GC response. Regulatory CD4+ T cell–derived IL-10 is important for.

Regulatory CD4+ T cell–derived IL-10 is important for B cell differentiation and the GC response. Regulatory CD4+ T cell–derived IL-10 is important for.
LV activation of DCs and subsequent CD8+ T cell priming are dependent on STING and cGAS but not on MyD88, TRIF, or MAVS. LV activation of DCs and subsequent.

LV activation of DCs and subsequent CD8+ T cell priming are dependent on STING and cGAS but not on MyD88, TRIF, or MAVS. LV activation of DCs and subsequent.
Human PBMC-derived MERS-CoV–specific T cells are multifunctional.

Human PBMC-derived MERS-CoV–specific T cells are multifunctional.
Group data during free walking between sessions 1 and 16.

Group data during free walking between sessions 1 and 16.
Virus-specific T cell responses are detected in all MERS survivors.

Virus-specific T cell responses are detected in all MERS survivors.
Platelets are required for hFcγRIIA-induced anaphylaxis.

Platelets are required for hFcγRIIA-induced anaphylaxis.
NRP1-expressing myeloid cells influence adipocyte hypertrophy, development of fatty liver, and CLSs. NRP1-expressing myeloid cells influence adipocyte.

NRP1-expressing myeloid cells influence adipocyte hypertrophy, development of fatty liver, and CLSs. NRP1-expressing myeloid cells influence adipocyte.
Human cells produce type I and III IFNs upon Af stimulation.

Human cells produce type I and III IFNs upon Af stimulation.
Macrophage-resident NRP1 promotes FA uptake.

Macrophage-resident NRP1 promotes FA uptake.

Similar presentations

Ads by Google