Presentation on theme: "Chelatometry. Introduction of biogenic elements chemistry"— Presentation transcript:
1Chelatometry. Introduction of biogenic elements chemistry LECTURE 3Chelatometry. Introduction of biogenic elements chemistryass. prof. Ye. B. Dmukhalska
2MINERALS Basic functions performed by the minerals are: 1. As structural components of body tissues.2. In the maintenance of acid-base balance.3. In the regulation of body fluids.4. In transport of gases.5. In muscle contractions.
3In the human body and animals are near 70 chemical elements, but 47 are called biogenic elements Six elements: carbon, hydrogen, oxygen, nitrogen, phosphorus, sulfur; are on amino acid, basic components of albumen, and they are named organogenic.94 % of all living tissues contain only 4 elements: carbon, hydrogen, oxygen, nitrogen.
4Depending on quantitative maintenance all elements classified into macro-, micro- and ultramicroelements.The macroelements are elements which more then 0,01 % of body mass are on organism. It is sodium, potassium, calcium, phosphorus, chlorine, sulfur, magnesium.The microelements – 10-3–10-5 %. It is an iodine, bromine, fluorine, iron, copper, aluminium, magnesium, cobalt, zinc, strontium, lithium, selenium, molybdenum.The ultramicroelements are elements which lest then 10-5 %. It is a mercury, gold, chrome, silicon, nickel.
6Coordination compounds are the compounds in which the central metal atom is linked to а number of ions or neutral molecules by coordinate bonds i.е. by donation of lone pairs of electrons by these ions or neutral molecules to the central metal atom.nickel tetracarbonyl, [Ni(CO)4]
7the species formed by linking of а number of ions or molecules by co-ordinate bonds to the central metal atom (or ion) carries positive or negative charge, it is called a complex ion. [Fe(СN)6]4-, [Cu(NH3)4]2+, [Ag(CN)2]-
8The donor atoms, molecules or anions, which donate а pair of electrons to the metal atom and form co-ordinate bond with it are called ligands.
9If only one donor atom is present in its molecule, which can coordinate, then it is called as unidentate (monodentate). : NH3, Н2О and CN-.The ligand may contain two donor atoms (coordinating groups) positioned in such а way then it is called bidentate chelating ligandThe ring is called chelate ring and the resulting complex is called а metal chelate.
10The complexes formed by Cu (II) and Pt (II) ions with ethylenediamine are metal chelates represented as follows:
12Some important characteristics of chelates. (i) Chelating ligands form more stable complexes than the monodentate analogs. This is called chelating effect.(ii) Chelating ligands, which do not contain double bonds e.g. ethylenediamine form five membered stable rings. The chelating ligands such as acetylacetone form six membered stable ring complexes.(iii) Ligands with large groups form unstable rings than the ligands with smaller groups due to steric hindrance.
13Coordination number. The total number of monodentate ligands (plus double the number of bi dentate ligands if any) attached to the central metal ion through coordinate bonds is called the coordination number of the metal ion.[Ag(СN)2]-, [Cu(NН3)4]2+ and [Cr(Н2О)6]3
14Coordination sphere.The central atom and the ligands which are directly attached to it are enclosed in square brackets and are collectively termed as the coordination sphere.
15Oxidation number or oxidation state. It is а number that represents an electric charge which an atom or ion actually has or appears to have when combined with other atoms,oxidation number of copper in [Cu(NH3)4]2+ is +2 but coordination number is 4.oxidation number of Fe in [Fe(СN)6]3- is + 3 but the coordination number is 6.(i) [Cu (NНЗ)4]SO4.(ii) Fe in [Fe (СN)6]3-(iii)К3[Fe(С2О4)3].(iv) [Ni(CO)4].
16Charge on the complex ion. The charge carried by а complex ion is the algebraic sum of the charges carried by central metal ion and the ligands coordinated to the central metal ion.[Ag (CN)2]-[Cu (NH3)4]2+
21(ii) Neutral ligands have no special ending: NН3 (ammine), Н2О (aqua), CO (carbonyl), CS (thiocarbonyl) and NO (nitrosyl)
22(iii) Positive ligands (which are very few) end in -ium, е. g (iii) Positive ligands (which are very few) end in -ium, е.g., NН3+ (hydrazinium), NO+ (nitrosonium), NО2+ (nitronium).
23(iv) Organic ligunds. Organic free radicals are given their own names (iv) Organic ligunds. Organic free radicals are given their own names. For example, СН3 (methyl), С2Н5 (ethyl), С6Н5 (phenyl), С5Н5 (cyclopentadienyl).For organic neutral molecules, their names are used. For example, Р(С6Н5)3, triphenylphosphine;
24(v) Unidentate ligands with more than one co-ordinating atoms (v) Unidentate ligands with more than one co-ordinating atoms. It is essential to designate the point of attachment of а ligand by placing the symbol of the donor atom attached after that; name of the groups separated by hyphen. These ligands are called ambidentate ligands е.g., in thiocyanate and nitrite ions, we have two options each.— SCN, thiocyanate NО2- nitro— NCS, isothiocyanate - ONO, nitrite
26Types of complexes.(i) А complex in which the complex ion carries а net positive charge is called cationic complex: [Co(NН3)]3+, [Ni(NH3)6]2+(ii) А complex in which the complex ion carries а net negative charge is called anionic complex: [Ag(CN)2]-, [Fe (CN)6]4-(iii) А complex carrying no net charge is called а neutral complex or simply а complex:[Ni(CO)4], [CoCl3 (NН3)3]
27Main types of complex compounds 1. With one central atomAmmonia complex [Cu(NH3)4]SO4Aqua complex[Al(H2O)6]Cl3acidic complex K2[PtCl4]complex with difference ligands K[Pt(NH3)Cl3]cyclic (chelates)Polycentral compoyndsChain [Cr(NH3)5 – OH – (NH3)Cr]Cl3chelaes (CO)5Mn – Mn(Co)5COCH2NH2CHOOCCOOHMeMeNH2CH2MeOC