1. Biomarkers in endometriosis: challenges and opportunities
Soo Hyun Ahn, M.Sc., Vinay Singh, Ph.D., Chandrakant Tayade, D.V.M., Ph.D. 
Fertility and Sterility 
Volume 107, Issue 3, Pages (March 2017)
DOI: /j.fertnstert
Copyright © 2017 American Society for Reproductive Medicine Terms and Conditions

2. Figure 1
Cross-talk between the ectopic foci and eutopic endometrium. Chronic inflammation induced by the ectopic presence of endometrial fragments (damage-associated molecular patterns [DAMPs]) lead to potential epigenetic modification programming within the eutopic endometrium. Aberrant regulation of gene transcription and post-translational regulatory mechanisms through noncoding RNAs likely contribute to development of progesterone resistance and heightened response to estrogen, which are two key characteristics of the eutopic endometrium of women with endometriosis. In addition, chronic inflammation leads to hypersensitization of nerve fiber endings characterized by enhanced neuronal connectivity in areas of pain perception. lncRNA = long noncoding RNA; miRNA = microRNA.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2017 American Society for Reproductive Medicine Terms and Conditions