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Aromatase, microRNA, and inflammation: a complex relationship

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Presentation on theme: "Aromatase, microRNA, and inflammation: a complex relationship"— Presentation transcript:

1 Aromatase, microRNA, and inflammation: a complex relationship
Serdar E. Bulun, M.D., Camran Nezhat, M.D.  Fertility and Sterility  Volume 106, Issue 3, Pages (September 2016) DOI: /j.fertnstert Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Based on this article by Cho et al. (5), we speculate that a complex feedback loop regulates the levels of aromatase, estrogen, ERβ, and let-7f in endometriosis. Solid arrows indicate stimulation, whereas interrupted lines indicate inhibition. The roles of estrogen and ERβ were postulated based on previously published data (2). There are possibly additional unknown steps between estrogen and let-7f and also between let-7f and aromatase mRNA. PGE2, prostaglandin E2. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions


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