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Winthrop Prof. Paul Abbott Director of Postgraduate Studies & Research School of Dentistry and the Oral Health Centre of WA.

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Presentation on theme: "Winthrop Prof. Paul Abbott Director of Postgraduate Studies & Research School of Dentistry and the Oral Health Centre of WA."— Presentation transcript:

1 Winthrop Prof. Paul Abbott Director of Postgraduate Studies & Research School of Dentistry and the Oral Health Centre of WA

2 Isolating Epithelial Cells of Malassez for Therapeutic Analysis Isolating Epithelial Cells of Malassez for Therapeutic Analysis Marisa de Pinho Background: Epithelial cells are notoriously very difficult to grow – need to enhance this growth Aim is to isolate, cultivate and purify epithelial cells of Malassez from human PDL fibroblasts Mediums to be investigated: EpiLife ® (Invitrogen) – human epithelial cell medium Keratinocyte-SFM ® (Invitrogen) – keratinocyte serum free medium KBM-Gold ® (Lonza) – keratinocyte cell basal media MCB ® – specific epithelial cell of Malassez medium

3 Assoc. Prof. Tony Phan

4 Tissue Engineering & Regeneration Fa-Ming Chen, Yan Jin. Tissue Engineering Part B: Reviews. April 2010, 16(2):

5 The SLURP family of Proteins Secreted mammalian Ly-6/Urokinase-type plasminogen activator receptor-Related Protein Lymphocyte Antigen 6 (Ly-6) Superfamily Function: cellular differentiation cell growth cell survival motility Glycosylphosphatidylinositol (GPI) -membrane linked

6 Flexcell System Vacuum pump Flexcell CPU Dr Danny Yang - PhD student

7 Tissue Regeneration in Oral Health: The effect of NGF and EGF on periodontal and pulp healing of replanted molars in a rat model Dr Estabelle Ang - Postdoc. Fellow

8 Autotransplantation of Teeth Premolar Incisor site Winthrop Prof. Paul Abbott

9 Managing Bone Resorption and External Inflammatory Root Resorption Winthrop Prof. Paul Abbott On referral1 yr - Ca(OH) 2 3 mths - Led. 6 mths - Led.

10 Using Endodontic Medicaments to Treat Root Resorption Winthrop Prof. Paul Abbott Pre-operativeRCF - 15 mths4 yrs - Review

11 Investigations into the Use of Interim Restorations During Endodontic Treatment Jensen A-L, Heffer RM, Hsu H-S, Abbott PV. Graduate Endodontic Program School of Dentistry University of Western Australia

12 Willytec Chewing Simulator

13 + Dye

14 Results StructuralIntegrity Group IntactDebonded GIC GIC10 15 (60%) Band Band250 During mastication - 2 During mastication - 2 Bacteria + Dye - 1 Bacteria + Dye - 1 Dye only - 1 Dye only - 1 During de-mounting - 1 During de-mounting - 1 Dye only - 1 Dye only - 1 During access cavity prep n to test CW - 12 During access cavity prep n to test CW - 12 Bacteria + Dye - 1 Bacteria + Dye - 1 Bacteria only - 3 Bacteria only - 3 Dye only - 2 Dye only - 2 Neither - 6 Neither - 6

15 I. DEVELOPMENT OF FUNCTIONALLY-GRADED DENTAL BIOMATERIALS Prof. Paul Ichim in collaboration with W/Prof. Xiaozhi Hu (Mechanical Engineering, UWA) ARC Discovery grant Development of a hydroxyapatite-containing ceramic composite core dental implant system with effective variable elastic properties II. DEVELOPMENT OF A NEW ENDODONTIC POST SYSTEM Prof. Paul Ichim in collaboration with Dr. Patrick Schmidlin (Faculty of Dentistry, Zurich). This project is funded by Ada Bartholomew research grant. III. DEVELOPMENT OF AN INDIRECT ASESSMENT OF CLINICAL COMPETENCY OF DENTAL STUDENTS Prof. Paul Ichim, A/Prof. Jennifer Bazen and W/Prof. Andrew Smith. External partners: School of Dentistry, University of Minessota. The project aims at delivering a competency-based clinical assessment in which the student performance is determined longitudinally by measuring the time spent by the faculty in assisting the student.

16 Assoc. Prof. Mithran Goonewardene Orthodontics Group

17 Histomorphometric Analysis of Bone Surrounding Loaded Microimplants Dr Angela Pathmanathan Aims: 1.To assess the changes in bone surrounding self-threaded and self- tapping implants over time. 2.To assess which implants have a more effective response that can be used during orthodontics to achieve ideal movement of teeth over a shorter time period.

18 Cephalometric investigation assessing the skeletal stability following Orthognathic Surgical Rotation of the Occlusal Plane Dr Rob Hamilton

19 Manipulation of Occlusal Plane

20 AIM Cephalometric investigation of the skeletal stability following orthognathic surgical treatment involving: Clockwise Counter- clockwise No-rotation

21 Student: Dr Chris Duigou Aims: 1. To investigate the treatment effects of using rapid maxillary expansion devices and facemasks on Class 3 patients. 2. To investigate candidate gene assessment to predict treatment response

22 The Value of Digital Model Diagnostic Set-up in Treatment Planning Complex Interdisciplinary Treatment Cases. Roy Goonewardene Mike Razza Mithran Goonewardene Kevin Murray

23 The value of a diagnostic set-up in treatment planning is generally acknowledged yet this has not been scientifically tested. Aim: To compare the efficacy of using both plaster and digital diagnostic casts for presentation of complex treatment plans to a group of restorative dentists. Moreover, the acceptability and value of using firstly a wax and plaster diagnostic set-up and secondly, digital models and setup will be evaluated. Relate years as a dentist/ IT familiarity and usage

24 + Repeat in Digital Format (on laptop computer) Paper/Film/Plaster Plaster/Wax setup

25 School of Dentistry 1. Dental Public Health 2. Dental Traumatology 3. Education & Assessment 4. Simulation Teaching 5. Endodontics 6. Materials Science Main Research Fields 7. Periodontics 8. Oral Cancer 9. Oral Medicine & Oral Pathology 10. Orthodontics 11. Oral & Maxillofacial Surgery 12. Tissue Regeneration and Auto-transplantation

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