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Could Fractional Exhaled Nitric Oxide Test be Useful in Predicting Inhaled Corticosteroid Responsiveness in Chronic Cough? A Systematic Review  Woo-Jung.

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Presentation on theme: "Could Fractional Exhaled Nitric Oxide Test be Useful in Predicting Inhaled Corticosteroid Responsiveness in Chronic Cough? A Systematic Review  Woo-Jung."— Presentation transcript:

1 Could Fractional Exhaled Nitric Oxide Test be Useful in Predicting Inhaled Corticosteroid Responsiveness in Chronic Cough? A Systematic Review  Woo-Jung Song, MD, Ha-Kyeong Won, MD, Sung-Do Moon, MD, Soo-Jie Chung, MD, Sung-Yoon Kang, MD, Kyoung-Hee Sohn, MD, Ju-Young Kim, MD, Byung-Keun Kim, MD, Kyung-Hwan Lim, MD, Mi-Yeong Kim, MD, Min-Suk Yang, MD, PhD, Heung-Woo Park, MD, PhD, Yoon-Seok Chang, MD, PhD, Byung-Jae Lee, MD, PhD, Alyn H. Morice, MD, FRCP, Sang-Heon Cho, MD, PhD  The Journal of Allergy and Clinical Immunology: In Practice  Volume 5, Issue 1, Pages e1 (January 2017) DOI: /j.jaip Copyright © Terms and Conditions

2 Figure 1 Preferred Reporting Items for Systematic Reviews and Meta-Analyses for study selection. The Journal of Allergy and Clinical Immunology: In Practice 2017 5, e1DOI: ( /j.jaip ) Copyright © Terms and Conditions

3 Figure 2 Quality Assessment of Diagnostic Accuracy Studies 2 quality assessment of the included studies. A, Graph showing the risk of bias and concerns regarding applicability: review of authors' judgments in each domain, presented as percentages across the included studies. B, Risk of bias and concerns regarding applicability summary: review of authors' judgments in each domain for all included studies. The Journal of Allergy and Clinical Immunology: In Practice 2017 5, e1DOI: ( /j.jaip ) Copyright © Terms and Conditions

4 Figure 3 Forest plot summarizing the findings of each study regarding the usefulness of Feno tests for predicting ICS response in patients with chronic cough. The study of Watanabe et al21 indicates the results from steroid-naive samples. FN, False negative; FP, false positive; TN, true negative; TP, true positive. The Journal of Allergy and Clinical Immunology: In Practice 2017 5, e1DOI: ( /j.jaip ) Copyright © Terms and Conditions

5 Figure 4 Summary ROC curve for Feno tests with respect to prediction of ICS responsiveness among patients with chronic cough, subgrouped by study design. The study of Watanabe et al21 indicates the results from steroid-naive samples. The Journal of Allergy and Clinical Immunology: In Practice 2017 5, e1DOI: ( /j.jaip ) Copyright © Terms and Conditions

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