1. From: Effects of Shear Stress on the Gene Expressions of Endothelial Nitric Oxide Synthase, Endothelin-1, and Thrombomodulin in Human Retinal Microvascular Endothelial Cells
Invest. Ophthalmol. Vis. Sci ;52(11): doi: /iovs
Figure Legend:
Flow circuit system and flow chamber. (A) The closed circuit, including the flow chamber, a peristaltic pump, and a medium reservoir, are connected by silicone tubes. (B) Structure of the parallel plate type flow chamber. The shear rate (γ̇, 1/s) and shear stress (τ, dyne/cm2) acting on the cells were calculated using the formulas: γ̇ = 6Q̇/(a2b) and τ = μ · γ̇, where Q̇ is the volumetric flow rate (mL/sec), a and b are the height and width (cm) of the channel in the cross section, and μ is the viscosity of the perfused fluid.
Date of download: 10/20/2017
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