1. BioTechnikum Greifswald Center for Biotechnology and Biomedicine

2. The mission Enterprises Products on market Science R&D - projects Incubator Technology Center,...

3. Life Sciences Incubator for enterprises from biotechnology and biomedicine Incubator for enterprises from biotechnology and biomedicine –OECD-definition: … the application of science and technology to living organisms as well as parts, products and models thereof, to alter living or non-living materials for the production of knowledge, goods and services –Including biotechnology related areas like medicine and medical technology

4. In brief Total area8600 m² Total area8600 m² –Laboratories / Offices4300 m² –General laboratories / equipment for all320 m² –Conference rooms840 m² –Technical equipment1600 m² Total investment ~ 21 Mio. Total investment ~ 21 Mio. –Extension 1 (1999)~ 160 Tsd. –Extension 1 (1999)~ 160 Tsd. –Extension 1 (1999)~ 420 Tsd. –Extension 1 (1999)~ 420 Tsd. –Extension 1 (1999)~ 1.800 Tsd. –Extension 1 (1999)~ 1.800 Tsd. Finanzierung Finanzierung –Public funds (Land, Federal Republic, EU) 90% –Hansestadt Greifswald 10% (resp. BioTechnikum Greifswald GmbH) Management by specific management company Management by specific management company

5. BioTechnikum Greifswald GmbH Owner marketing & management BioTechnikum Greifswald GmbH Hansestadt Greifswald 25 year contract Shareholders Hansestadt Greifswald51% Ernst Moritz Arndt-Univ.38% BioCon Valley M-V e.V.9% Dresdner Bank AG2 % Board Hansestadt Greifswald1 Greifswald University.1 BioCon Valley M-V e.V.1 Dresdner Bank AG1 Ministery of Economics1 Town council- Staff. Full time4/(5). Part time2. Studentsn

6. Laboratories Laboratories with basic equipment, modular units (> 50 m²) with office in direct neighbourhood Laboratories with basic equipment, modular units (> 50 m²) with office in direct neighbourhood Laboratories fulfil requirements according GenTG (German Gene Technology Law), biosafety standards 1/2 available, upgradable to 3 Laboratories fulfil requirements according GenTG (German Gene Technology Law), biosafety standards 1/2 available, upgradable to 3 Laboratories supplied with standard technical infrastructure (water, gas, compressed air; other gases on request) Laboratories supplied with standard technical infrastructure (water, gas, compressed air; other gases on request) Access to central facilities (fermentation, isotope laboratory, cold room, centrifuge room) Access to central facilities (fermentation, isotope laboratory, cold room, centrifuge room) Utilisation of central equipment (e.g. DNA-/RNA-synthesis, protein peptide preparation and -analytics, cell cultivation and manipulation) Utilisation of central equipment (e.g. DNA-/RNA-synthesis, protein peptide preparation and -analytics, cell cultivation and manipulation)

7. Occupancy Launch of German BioRegio Contest

8. ... Tenants 2001 R&D Enter- prises Rented space 1997 biometec GmbH Adexter GmbH (Bioserv AG) Bioserv Medizinprodukte GmbH Chromatec GmbH Decodon GmbH [euromed A. Pein] Ganomycin GmbH Hygiene Nord GmbH [[Institut für Umwelttechnologie GmbH]] [IWE GbR] Mediwirk GmbH Micromun GmbH [Promedicontrol GmbH] Syntrex GbR (Synaptec GmbH) [URST GmbH] [advanced IT.net solutions GmbH] [BBJ Servis GmbH] idee Gentner-Schidlowski GbR Ingenieurbüro Vogt [Dr. Heydenreich GmbH (iX-Ware GmbH)] Stadlmüller consult VISUV GbR biocomp-Network Centrum für angewandte Telemedizin Forschungsverbund Mecklenburg-Vorpommern Institut für angewandte Telemedizin Institut für marine Biotechnologie [Institut für Niedertemperatur-Plasmaphysik] Institut für Pigmentationsstörungen e.V. [Institut für Plasmaphysik] [Technologietransferstelle Biotechnologie] Universität Greifswald

9. Case Studies – R&D e.g. Institute Marine Biotechnology e.V. foundet 1996 as association for public benefit foundet 1996 as association for public benefit As Building Block of regional BioRegio concept (USP) As Building Block of regional BioRegio concept (USP) Applied Research on marine microorganisms Applied Research on marine microorganisms –Screening for new drugs –Screening for new enzymes –Reference lab for proteomics Organizer of the int. Conferences on Marine Biotech; June 21-24, 2005 in Greifswald, Germany (4rth event) Organizer of the int. Conferences on Marine Biotech; June 21-24, 2005 in Greifswald, Germany (4rth event) Spin off company Spin off company –Ganomycin GmbH: new antibiotics from funghi Springboard for start up´s www.marine-biotechnologie.de

10. Case Studies – Start up Company e.g. DECODON GmbH Idea of mol. Biologists, IT programmer, mathemat. Idea of mol. Biologists, IT programmer, mathemat. 1rst meeting by chance in BioTechnikum to discuss new projects 1rst meeting by chance in BioTechnikum to discuss new projects Realize IT tools for functional genomics (bioinformatics) Realize IT tools for functional genomics (bioinformatics) Start in 2002 Start in 2002 Launch Delta2D Launch Delta2D patronage by university professor (internatl. expert in Proteomics) patronage by university professor (internatl. expert in Proteomics) 2005 big Deal with Fuji Life Science, Japan 2005 big Deal with Fuji Life Science, Japanwww.decodon.com

11. ... financial status Public funding Land / Hansestadt Costs Tenants fees, other services BioRegio... on the way to BioCon Valley Launch of German BioRegio Contest

12. Networks Goal: Catalysis of Collaboration Catalysis of Collaboration Marketing Marketing Branding/Image Branding/Image Build up Critical Mass Regional (since 1996/2001) Regional (since 1996/2001) – BioRegio [Greifswald-Rostock] / BioCon Valley – BioRegio [Greifswald-Rostock] / BioCon Valley National (since 1996) National (since 1996) – Partner of German BioRegions International (since 2001) International (since 2001) – ScanBalt – borderless biotech: Network of Life Science Networks in the Baltic Sea Region www.biotechnikum.de - www.bcv.org - www.bioregio.com - www.scanbalt.org [Goto ScanBalt]