1. Welcome to: Cell Regulation and Signaling Or Cell Signaling and Regulation KMB613

2. Course taught by experts in their fields!

3. Requirements for Zápočet Present an journal club article Mandatory attendace of journal club You are allowed ONE absence Please come see me if you have think you will be absent for a extended time during the semester Foreigners going home Research stays

4. Guidelines for journal club presentation 1 of 3 Journal club starts 5-10 minutes after the end of the lecture!!! Not at 17.15 as stated in the official schedule Presenters MUST be here 5-10 minutes afterwards ready to present otherwise they did not fulfill the requirement!!! Therefore it is in your interest to show up for the lecture before your presentation because it ends when it ends Do not frantically work on your presentation DURING the lecture-I will kick you out. Bottom line – last second for finishing your presentation is at the start of the class!

5. Guidelines for journal club presentation 2 of 3 Many of the papers have supplementary data Please look at this Many have films or summary schemes that should be included in your presentations if they work better than the static figures! You don’t have to present all the figures, just the ones that convey the main points The presentation should be 20-30 minutes long

6. Guidelines for journal club presentation 3 of 3 The presentation should be about 20 minutes long You should give a brief intro to the topic or techniques used if specialized (eg not Western, Northern, real-time PCR, etc.) You should discuss the main aims and conclusions of paper You should discuss the relevance of the paper and say why you think it was accepted into Science, Nature, Cell, etc.

7. Final exam for your grade Multiple choice exam 2 questions from each lecture The tests will become increasingly difficult with each successive test term! The earlier the term, the easier the test!

8. Extra points for the test 3+ points on test for asking questions during journal club. Number of journal clubs for participation You must reach a threshold number that I will say on last day of class 3+ points for pop quizzes Yes, there will be surprise quizzes about the journal articles. One question about article-either you get it right or wrong Threshold number at end of class 3, 2, 1+ for best, 2 nd best and 3 rd best presentation determined by me at end of course

9. Course web site where lectures and journal club articles are posted: One the Dept Molecular Biology website: http://kmb.prf.jcu.cz/en “Study materials → Cell Signaling” -or- English: http://kmb.prf.jcu.cz/en/en-materials/study- materials/cell-regulation-and-signaling-844497 Czech (just web, not materials): http://kmb.prf.jcu.cz/cs/studijni- materialy/studijni-materialy-777029/bunecne- regulace-a-signalizace

10. Let's divvy up the journal club talks No, you cannot choose a paper related to your research topic