1. Warmup 3/8/16 What do you know about the immune system? Objective Tonight’s Homework To learn about the lymphatic system pp 569: 1, 2, 3, 4 Research an autoimmune disorder

2. Notes on the Lymphatic System As we’ve discussed, there are many substances that travel in the blood. When blood reaches capillaries, many of these substances are absorbed into surrounding cells. Not all of these substances are good, though. Substances that the body can’t use are squeezed between cells until they enter tiny little vessels meant to hold waste. These vessels are part of the lymphatic system. Once waste enters these vessels, we call it lymph.

3. Notes on the Lymphatic System The lymphatic system runs in tiny vessels throughout your entire body. These vessels do not connect to your circulatory system and don’t have a heart to assist in pumping. Instead they rely on the contraction and motion of muscles throughout your body to squeeze and push fluids.

4. Notes on the Lymphatic System These vessels are designed like one-way doors. The pressure outside the lymph vessels is greater than that inside, so materials push their way in but then can’t push back out. This keeps waste materials in the system and out of the rest of the body.

5. Notes on the Lymphatic System Scattered throughout the lymphatic system are sections called lymph nodes. These nodes range from pinprick to lima bean size and store most of the waste collected by the system. These are most common in the neck, armpit, head, and groin.

6. Notes on the Lymphatic System Lymph nodes contain 2 types of cells. - lymphocytes, which are designed to attack specific bacteria and viruses when you’re sick - macrophages, which are large cells that function like white blood cells to attack and digest anything foreign.

7. Notes on the Lymphatic System Lymph nodes contain 2 types of cells. - lymphocytes, which are designed to attack specific bacteria and viruses when you’re sick - macrophages, which are large cells that function like white blood cells to attack and digest anything foreign. Macrophages can be either wandering or fixed. Wandering can move about the body freely, while fixed are embedded in lymph nodes.

8. Notes on the Lymphatic System When you get sick, many bacteria or viruses make it into the lymphatic system. These invaders are often destroyed by the fixed macrophages in the first lymph node they meet. Sometimes, this is all the defense your body needs to fight off the infection. However, if you’re really sick, the invaders can overwhelm a lymph node and often make it to the second or third node they encounter. In rare cases, the invaders will take over a node, causing it to swell up and be a site of pathogen production rather than destruction.

9. Notes on the Lymphatic System All lymphatic vessels eventually drain into the subclavian veins in your chest, ideally cleared of most of their waste products by this point. Any remaining products are filtered out by the kidney or liver.

10. Researching an Autoimmune Disorder By the end of the week, we’re going to be talking about autoimmune disorders and allergies. There are a lot of interesting ones. Your job by Friday is to research an autoimmune disorder and make a small (construction paper sized) poster. Your poster needs to include the following: 1) The name of the disorder 2) What that disorder does to the body 3) How people get the disorder and who it most affects 4) What treatment options there are for this disorder

11. Coloring Lymphatic System We have the rest of class to start coloring the lymphatic system.

12. Exit Question What is the main function of a lymph node? a) To create white blood cells b) To store waste material before it goes to the intestines c) To store extra blood when not in circulation d) To move materials through the body quickly e) To aid in storing reproductive cells f) None of the above