1. Date of download: 6/2/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Long-term Use of Inhaled Corticosteroids and the Risk of Pneumonia in Chronic Obstructive Pulmonary Disease: A Meta-analysis Arch Intern Med. 2009;169(3):219-229. doi:10.1001/archinternmed.2008.550 Flowchart describing study selection and excluded studies. COPD indicates chronic obstructive pulmonary disease; RCT, randomized controlled trial. Figure Legend:

2. Date of download: 6/2/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Long-term Use of Inhaled Corticosteroids and the Risk of Pneumonia in Chronic Obstructive Pulmonary Disease: A Meta-analysis Arch Intern Med. 2009;169(3):219-229. doi:10.1001/archinternmed.2008.550 Meta-analysis of randomized controlled trials of inhaled corticosteroid (ICS) use vs control treatment for any pneumonia. CI indicates confidence interval; LABA, long-acting β-agonist. Figure Legend:

3. Date of download: 6/2/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Long-term Use of Inhaled Corticosteroids and the Risk of Pneumonia in Chronic Obstructive Pulmonary Disease: A Meta-analysis Arch Intern Med. 2009;169(3):219-229. doi:10.1001/archinternmed.2008.550 Meta-analysis of randomized controlled trials of inhaled corticosteroid (ICS) use vs control treatment for serious pneumonia. CI indicates confidence interval; LABA, long-acting β-agonist. Figure Legend:

4. Date of download: 6/2/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Long-term Use of Inhaled Corticosteroids and the Risk of Pneumonia in Chronic Obstructive Pulmonary Disease: A Meta-analysis Arch Intern Med. 2009;169(3):219-229. doi:10.1001/archinternmed.2008.550 Meta-analysis of randomized controlled trials of inhaled corticosteroid (ICS) vs control for pneumonia-related mortality. CI indicates confidence interval; LABA, long-acting β-agonist. Figure Legend:

5. Date of download: 6/2/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Long-term Use of Inhaled Corticosteroids and the Risk of Pneumonia in Chronic Obstructive Pulmonary Disease: A Meta-analysis Arch Intern Med. 2009;169(3):219-229. doi:10.1001/archinternmed.2008.550 Meta-analysis of randomized controlled trials of inhaled corticosteroids (ICS) vs control for overall mortality. In the Forest plot, the white horizontal line within the black box for Calverley et al indicates the 95% confidence interval (CI). LABA, indicates long-acting β-agonist. Figure Legend: