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Juvenile Dermstomyositis Kannemirova M.G.. Dermstomyositis «Дерматомиозитные очки» -- отечность и эритематозные высыпания с лиловым оттенком в параорбитальной.

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Presentation on theme: "Juvenile Dermstomyositis Kannemirova M.G.. Dermstomyositis «Дерматомиозитные очки» -- отечность и эритематозные высыпания с лиловым оттенком в параорбитальной."— Presentation transcript:

1 Juvenile Dermstomyositis Kannemirova M.G.

2 Dermstomyositis «Дерматомиозитные очки» -- отечность и эритематозные высыпания с лиловым оттенком в параорбитальной области Heliotrope is often associated with periorbital edema and telangiectasias of the upper eyelids. In the resolution stage, atrophy or dyspigmentation (hypo- or hyperpigmentation) may be apparent. Heliotrope. Subtle erythema and minimal edema involving both upper eyelids, with extension to the lower eyelids.

3 Dermstomyositis Heliotrope. Confluent macular erythema confined to the upper eyelid, with associated periorbital edema

4 Juvenile Dermstomyositis Malar and facial erythema and oedema. Acute onset of confluent macular erythema in a periorbital and malar distribution with extension to the chin in a boy with juvenile dermatomyositis. Note the perioral sparing

5 Juvenile Dermstomyositis Gottron's papules. Discrete erythematous papules overlying the metacarpal and interphalangeal joints in a patient with juvenile dermatomyositis

6 Juvenile Dermstomyositis Gottron's papules. Erythematous to violaceous raised papules overlying the metacarpal and interphalangeal joints in a patient with juvenile dermatomyositis

7 Juvenile Dermstomyositis Gottron's papules. Erythematous plaques overlying the elbows in two patients with juvenile dermatomyositis. In some patients, small erythematous plaques may overly the extensor aspects of larger joints, such as the elbows, knees, and medial malleoli. This is considered to be an extended part of the spectrum of Gottron's papules.

8 Juvenile Dermatomyositis Gottron's papules showing secondary atrophy and telangiectasia in a girl with severe juvenile dermatomyositis. These changes are seen in association with prominent periungual erythema, a cutaneous finding indicative of ongoing disease activity.

9 Juvenile Dermatomyositis Gottron's papules showing secondary atrophy and telangiectasia

10 Dermatomyositis Gottron's papules on the dark skin seems black. *Г. Готтрон (Heinrich A. Gottron, 1890-1974) - немецкий терапевт.

11 Juvenile Dermatomyositis Subcutaneous Ca- nodules over the elbows with inflammatory changes

12 Juvenile Dermatomyositis Muscular calcinosis.

13 Juvenile Dermatomyositis General dystrophy – the outcome of Juvenile Dermatomyositis

14 Medications to help relieve symptoms include: Prednisolone Methotrexate Mycophenolate (CellCept / Myfortic) immunosuppressant drugMycophenolate immunosuppressant Intravenous immunoglobulin Azathioprine Cyclophosphamide Rituximab[8]-is a chimeric monoclonal antibody against the protein CD20,Rituximab[8]chimericmonoclonal antibodyCD20

15 Polyarteritis nodosa American College of Rheumatology criteria: Weight loss greater than/equal to 4.5 kg. Livedo reticularis (a mottled purplish skin discoloration over the extremities or torso).Livedo reticularis Testicular pain or tenderness. (occasionally, a site biopsied for diagnosis). Muscle pain, weakness, or leg tenderness. Nerve disease (either single or multiple). Diastolic blood pressure greater than 90mmHg (high blood pressure). Elevated kidney blood tests (BUN greater than 40 mg/dl or creatinine greater than 1.5 mg/dl).creatinine Hepatitis B virus tests positive (for surface antigen or antibody).Hepatitis B Arteriogram (angiogram) showing the arteries that are dilated (aneurysms) or constricted by the blood vessel inflammation.Arteriogramaneurysms Biopsy of tissue showing the arteritis (typically inflamed arteries).[6][6]


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