Presentation on theme: "THE EVIDENCE THIS KEY STUDY WAS RECEIVED WITH ACCLAIM AT THE NATIONAL ACADEMY OF BURNS, INDIA CONFERENCE, LUDHIANA, INDIA. 22 FEBRUARY, 2015."— Presentation transcript:
THE EVIDENCE THIS KEY STUDY WAS RECEIVED WITH ACCLAIM AT THE NATIONAL ACADEMY OF BURNS, INDIA CONFERENCE, LUDHIANA, INDIA. 22 FEBRUARY, 2015
ABOUT THE STUDY: 30 patients with second degree burns were treated with wheatgrass extract (WHEATFIX BURN SPRAY) And compared with standard silver sulfadiazine dressings. MAJOR FINDINGS: A. PAIN RELIEF 93% OF PATIENTS IN THE WHEATGRASS GROUP WERE COMPLETELY RELIEVED OF PAIN WITHIN 24 HOURS whereas none of the SSD (SILVER SULFADIAZINE OINTMENT) treated patients experienced pain relief.
Pain relief within 24 hours Wheatgrass Group SSD Group No.% % Pain completely relieved 2893.3%00.0 Not relieved26.730100.0 Total30100.0030100.00. Pain Relief Comparison Wheatgrass extract vs. SSD within 24 hours of application. Distribution of patients according to pain relief within 24 hours 93% OF PATIENTS RELIEVED OF PAIN WITHIN 24 HOURS WITH WHEATFIX BURN SPRAY COMPARED WITH NO PAIN RELIEF AT ALL USING SILVER SULFADIAZINE
B. RATE OF WOUND HEALING THE HIGHLIGHTED NUMBERS IN THE TABLE BELOW SHOW THAT BURN WOUND RECOVERY RATE WAS 64% FASTER THAN SSD. Mean Days of Wound Healing Wheatgrass Group SSD Group (mean ± SD) Days to Heal Wound 8.77 ± 4.0613.77 ± 1.43
OBSERVATIONWHEATGRASS EXTRACT SILVER SULFADIAZINE DAYS TO HEAL 8.813.8 PAIN SCORE 1.34.7 PAIN RELIEF WITHIN 24 HOURS 93.3%NIL SUMMARY OF RESULTS WHEATGRASS EXTRACT VS. SILVER SULFADIAZINE
BURN STUDY RESEARCHERS’ OBSERVATIONS: Children were most benefited by wheatgrass as no sedative was necessary, but was required by the majority of patients with SSD dressings. Pain relief started after one hour using wheatgrass and lasted for about 8-10 hours with minimal analgesic requirement for breakthrough pain. Analgesics had to be given round the clock with SSD dressing patients. Patient compliance with wheatgrass extract was better as the wound did not require dressings
MORE OBSERVATIONS FROM THE RESEARCHERS: Dressing application with SSD was cumbersome while with wheatgrass extract it was simple to just spray it on the wound. No hypersensitivity or adverse effects were seen with wheatgrass extract. Wheatgrass extract was found to be safe. Wound infection was nil with wheatgrass as there was no obvious discharge or slough over the wound area. Wounds in the wheatgrass group were kept open so one could observe the efficacy of wheatgrass as well as eliminating the adverse effects of occlusive dressings, moist environment and Vaseline gauze normally used in the treatment of burns. Parents of children with burns were satisfied with wheatgrass as there was no psychological trauma to children since it was a simple spray. This ensured that children returned for regular follow up without fear of dressing change.
ADDITIONAL OBSERVATIONS MADE DURING THE STUDY Patients benefited most from wheatgrass extract because only minimal analgesia was required in a few patients. Compliance with wheatgrass extract was greater as the wound did not require dressings By comparison, because the SSD group required dressings which aggravate fresh burn surfaces, the majority required analgesia. Pain relief commenced after one hour using wheatgrass and lasted for about 8-10 hours with minimal analgesia required in a few for breakthrough pain. In the SSD group, analgesics were required round the clock.
PICTORIAL EVIDENCE OF WHEATFIX BURN SPRAY EFFICACY FOR TREATMENT OF SECOND DEGREE BURNS Day 1. Large burn area anterior thigh. Pre-wheatgrass treatment. Day 7. New skin forming over wound. No inflammation, exudate or infection. Day 15. Wound clean. Skin almost fully recovered. CASE #1.
Day 1. Pre-Wheatfix Burn Spray This child suffered second degree kerosene burns to his face. His pain ceased within 24 hours application with Wheatfix Burn Spray. Day 6. Note new, completely healed skin on left cheek, nose Day 3. Burn sealed. Pain-free. CASE #2.
Second degree burns to buttock region. Heavy exudate. Pre-wheatgrass treatment. Compare arrowed region with last picture (re-pigmentation). CASE #3. Day 3. Wounds almost completely dry and debrided. Reduced inflammation. No infection. Day 10. Wounds completely healed. Slight inflammation, no exudate and no sign of infection. Note re-pigmentation suggesting recovery of melanocytic function. (arrow)
RESEARCH ARTICLES SHOWING EFFICACY OF WHEATGRASS FOR TREATMENT OF FIRST AND SECOND DEGREE BURNS Wheatgrass extract effective for second degree burns Efficacy and tolerability of Fitostimoline in two different forms (soaked gauzes and cream) and Citrizan Gel in the topical treatment of second-degree superficial cutaneous burns. Martini, P., Mazzatenta, C. & Saponati, G. (2011) Derm. Res. and Practice; 2011, 1-8. Wheatgrass cream reduces skin toxicity from radiotherapy in breast cancer patients Wheatgrass extract as a topical skin agent for acute radiation skin toxicity in breast radiation therapy: A randomized controlled trial. Wheat J., Currie G., Coulter K. J. Aust. Trad. Med. Soc. 2006;12(3):135--137) Severe burns recover quickly with chlorophyll (2 cases) Severe burns recover quickly with chlorophyll (2 cases) Chlorophyll: A preliminary report of its use in two cases of second and third degree burns. Hawton, H. 1950. Med.J.Aust. 337-340. Biological activities of chlorophyll derivatives Biological activities of chlorophyll derivatives. Chernomorsky, S., Segelman, A. New Jersey Medicine. 1988; 85(8): 669-73
Wound infection, ulcers, burns, abscesses etc. Wound infection, ulcers, burns, abscesses etc. Chlorophyll in wound healing and suppurative disease. Bowers, W. 1947. Am. J. Surg. 1947;73:37-50. Human growth hormone influences skin growth, development & repair Growth hormone system: skin interactions Povoa, G., Diniz, L. An. Bras. Dermatol. vol.86 no.6 Rio de Janeiro Nov./Dec. 2011 Effect of wheatgrass juice on wound healing Effect of Triticum aestivum (wheatgrass) juice on wound healing in rats. Singh, J., Sethi, J. Yadav, M., Sood, S., Gupta, V. Intl. J. Nat. Prod. Sci. 2011; 1: 15-20. Chlorophyll for infected skin disorders and burns Chlorophyll for infected skin disorders and burns Dermatologic evaluation of yeast, tyrothricin, chlorophyll and nitrofurazone. Johnson, H. 1948. Arch. Dermatol. Syph. 57:348-351 Wheatgrass extract for radiation caused skin toxicity Wheatgrass Extract as a Topical Skin Agent for Acute Radiation Skin Toxicity in Breast Radiation Therapy Currie, G., Wheat, J. J. Australian Trad.-Med. Soc, 2006, 12(1): 7-11.