1. Laboratory Safety Training
A. R. Smith Department of Chemistry
What You Need To Know

2. Making The Pieces Fit CAS IARC HMIS OSHA EPA NTP NIOSH NFPA PEL CFR
PPE
CFR
MSDS
ERP
RTK – Right To Know
ANSI – American National Standards Institute
CHP – Chemical Hygiene Plan
CFR – Code of Federal Regulations
ERP – Emergency Response Plan
MSDS – Material Safety Data Sheet
PPE – Personal Protective Equipment
PEL – Permissible Exposure Limit
OSHA – Occupational Safety and Health Administration (Department of Labor)
NFPA – National Fire Protection Association
EPA – Environmental Protection Agency
NIOSH - National Institute for Occupational Safety and Health
HMIS – Hazardous Materials Identification System
IARC – International Agency for Research on Cancer
CAS – Chemical Abstracts Service
NTP – National Toxicology Program
RoC - Report on Carcinogens
RTK
CHP
RoC
ANSI

3. Regulatory Agencies & Standards
Applies to: Laboratories meeting any of the following four criteria: 1. Chemical manipulations are carried out on a laboratory scale. 2. Multiple chemical procedures or chemicals are used. 3. Protective laboratory practices and equipment are available and in common use. 4. The procedures involved are not part of a production process whose function is to produce commercial quantities of materials.
OSHNC -
U of Louisville

4. Key Compliance Issues
OSHA Laboratory Standard
Lab Safety Plan, training of staff, MSDSs, emergency plan, secure compressed gas cylinders, out-dated peroxide-formers
EPA/State Hazardous Waste regulations
Lids, labels, mixing incompatibles
Fire/Life Safety Codes
10 gal flammables limit, clear lab egress, hallway storage University policies Training, prevention of injuries, personnel policies, grant proposal review
I cannot find the specific regulation on out-dated peroxide-formers, labeling based on industry standards.
UNC EHS Manual

5. Training Topics Personal Protective Equipment (PPE)
Emergency Response Plan
MSDSs
Labels & Inventory
Location of First Aid & Accident Reports
Fire Extinguisher Training & Flammable Hazards
Hazardous Waste Procedures
Chemistry Stockroom
Safety Contact Information
Training Topics
Location of the Laboratory Safety Standard
Chemical Hygiene Plan
Engineering Controls
Health & Safety Hazards
Pre-Purchase Review of Products
Detection of Release or Presence of Hazardous Chemicals
(f) Employee information and training (f)(1) The employer shall provide employees with information and training to ensure that they are apprised of the hazards of chemicals present in their work area.
(f)(2) Such information shall be provided at the time of an employee's initial assignment to a work area where hazardous chemicals are present and prior to assignments involving new exposure situations. The frequency of refresher information and training shall be determined by the employer.
(f)(3) Information. Employees shall be informed of:
(f)(3)(i) The contents of this standard and its appendices which shall be made available to employees;
(f)(3)(ii) the location and availability of the employer's Chemical Hygiene Plan;
(f)(4)(ii) The employee shall be trained on the applicable details of the employer's written Chemical Hygiene Plan.

6. The Laboratory Safety Standard1
The Laboratory Safety Standard
OSHA Standard
29 CFR

7. (The Laboratory Safety Standard)1
OSHA Standard 29 CFR
Occupational Exposure to Hazardous Chemicals in Laboratories
(The Laboratory Safety Standard)
(f)(3)(i) “The contents of this standard and its appendices which shall be made available to employees;”
Remember, where OSHA says “shall” we don’t have a choice.

8. The Chemical Hygiene Plan2
The Chemical Hygiene Plan

9. The Chemical Hygiene Plan (CHP)2
The Chemical Hygiene Plan (CHP)
(e)
Should be capable of protecting employees from health hazards associated with hazardous chemicals in the laboratory
Should be readily available to employees
(e) Chemical hygiene plan -- General
(e)(1) Where hazardous chemicals as defined by this standard are used in the workplace, the employer shall develop and carry out the provisions of a written Chemical Hygiene Plan which is:
(e)(1)(i) Capable of protecting employees from health hazards associated with hazardous chemicals in that laboratory and
(e)(1)(ii) Capable of keeping exposures below the limits specified in paragraph (c) of this section.
(e)(2) The Chemical Hygiene Plan shall be readily available to employees, employee representatives and, upon request, to the Assistant Secretary.
(e)(3) The Chemical Hygiene Plan shall include each of the following elements and shall indicate specific measures that the employer will take to ensure laboratory employee protection;
So, we have a CHP for the University, and for the department. The codes can not be any less stringent than the lab standard – they can be more.
We have made our CHP pretty simple
Follow departmental safety rules
Use items in ACS books as a guide
Use this training

10. 2
Standard Operating Procedures
SOPs (e)(3)(i)
“Standard operating procedures relevant to safety and health considerations to be followed when laboratory work involves the use of hazardous chemicals”
(e)(3)(i)
Standard operating procedures relevant to safety and health considerations to be followed when laboratory work involves the use of hazardous chemicals;
(e)(3)(ii) Criteria that the employer will use to determine and implement control measures to reduce employee exposure to hazardous chemicals including engineering controls, the use of personal protective equipment and hygiene practices; particular attention shall be given to the selection of control measures for chemicals that are known to be extremely hazardous;
If you are using a procedure or chemical that is not specifically addressed in the CHP or the ACS books, then you must develop a SOP for your lab with regards to this. The SOP should be added to the CHP section of your manual.

11. Standard Operating Procedures2
Standard Operating Procedures
SOPs (e)(3)(i)
GUIDELINES FOR PREPARING SOP's
Three methods that can be used to write SOP's:
By Process: (distillation, synthesis, chromatography, etc.)
By Individual Hazardous Chemical: (arsenic, benzene, hydrochloric acid, etc.)
By Hazardous Chemical Class: (flammable, corrosive, oxidizer, etc.)
If you have to prepare an SOP…
Michelle has made a fill in PDF SOP, and example is in the manual
You can get guidance on filling it in at the MSU site
Michigan State University SOP

12. 3
Engineering Controls
Hoods, Showers & Eyewashes

13. 3
Fume Hoods
(e)(3)(iii)
“A requirement that fume hoods and other protective equipment are functioning properly and specific measures that shall be taken to ensure proper and adequate performance of such equipment;”

14. 3
Fume Hoods
(e)(3)(iii)
Each employee should be completely familiar with the proper use and operation of the fume hood in their lab
Information on this subject may be located in the ACS Publication provided in the departmental CHP.
Additional information may be found online at the links provided in section 3 of the “Detailed Information”
Do not use hoods for storage
Chemicals should be at least 6 inches from the front
Sash should be adjusted to maintain proper flow rate
A test strip should be secured to the vent to give visual indication of a problem
Clean up spills promptly

15. Fume Hoods Fume Hoods should be tested for flow rate at least annually3
Fume Hoods
(e)(3)(iii)
Fume Hoods should be tested for flow rate at least annually
Arrangements should be made as soon as possible to have the hoods in your lab tested
The test results should be posted in a conspicuous place on the hood
I would suggest checking the flow rate with/without doors propped open, to insure that flow rate is not interrupted.

16. 3
Showers & Eyewashes
29 CFR
Appendix A, D.
“Maintenance. Eye wash fountains should be inspected at intervals of not less than 3 months (6). Respirators for routine use should be inspected periodically by the laboratory supervisor (169). Other safety equipment should be inspected regularly. (e.g., every 3-6 months) (6, 24, 171).”
However, shower testing is specifically mentioned in the University CHP, therefore we are obligated to test them.
The second quote is from an answer to someone in an OSHA “Compliance Letter”
“The routine inspections of showers mentioned in Appendix A of Section is not a mandatory requirement for which OSHA would normally issue a citation.”

17. Showers & Eyewashes However… 3
ANSI Z358.1
However…
Because shower testing is specifically mentioned in the University CHP, we are obligated to test them
Testing is also mandated by ANSI “Devices must also be inspected annually to assure compliance with ANSI Z358.1 maintenance and testing requirements.”
ASU Safety Office

18. Health & Safety Hazards4
Health & Safety Hazards

19. Health & Safety Hazards4
Health & Safety Hazards
(e)(3)(viii)
“Provisions for additional employee protection for work with particularly hazardous substances. These include "select carcinogens," reproductive toxins and substances which have a high degree of acute toxicity. Specific consideration shall be given to the following provisions which shall be included where appropriate:”

20. Health & Safety Hazards4
(e)(3)(viii)(A)
Establishment of a designated area;
(e)(3)(viii)(B)
Use of containment devices such as fume hoods or glove boxes;
(e)(3)(viii)(C)
Procedures for safe removal of contaminated waste; and
(e)(3)(viii)(D)
Decontamination procedures.
For the really nasty stuff.
These would be select carcinogens and acutely toxic substances.

21. Health & Safety Hazards4
Health & Safety Hazards
Carcinogens
OSHA depends on the big sources of info on Cancer research.
IARC
NTP

22. Carcinogens 4 H & S Hazards
(e)(3)(viii)
H & S Hazards
IARC - International Agency for Research on Cancer
Monographs Programme on the Evaluation of Carcinogenic Risks to Humans
NTP - National Toxicology Program
10th Report on Carcinogens (RoC)
ACGIH - American Conference of Governmental Industrial Hygienists
OSHA – Regulated Carcinogens

23. Carcinogens IARC 4 H & S Hazards
(e)(3)(viii)
H & S Hazards
IARC
Group 1: The agent (mixture) is carcinogenic to humans.
Group 2A: The agent (mixture) is probably carcinogenic to humans.
Group 2B: The agent (mixture) is possibly carcinogenic to humans.
Group 3: The agent (mixture, or exposure circumstance) is not classifiable as to carcinogenicity in humans.
Group 4: The agent (mixture, exposure circumstance) is probably not carcinogenic to humans.
International Agency for Research on Cancer
Group 1: The agent (mixture) is carcinogenic to humans. The exposure circumstance entails exposures that are carcinogenic to humans.
Group 2A: The agent (mixture) is probably carcinogenic to humans. The exposure circumstance entails exposures that are probably carcinogenic to humans.
Group 2B: The agent (mixture) is possibly carcinogenic to humans. The exposure circumstance entails exposures that are possibly carcinogenic to humans.
Group 3: The agent (mixture, or exposure circumstance) is not classifiable as to carcinogenicity in humans.
Group 4: The agent (mixture, exposure circumstance) is probably not carcinogenic to humans.

24. 4
Carcinogens
(e)(3)(viii)
H & S Hazards
NTP 10th RoC
Group 1 "Known Carcinogen" (Sufficient information from human studies to indicate causal relationship)
Group 2 "Reasonably Anticipated" (Limited evidence of carcinogenicity in humans; or sufficient evidence of carcinogenicity in experimental animals)
National Toxicology Program
Designations are Group 1Group 2"Known Carcinogen" (Sufficient information from human studies to indicate causal relationship)"Reasonably Anticipated" (Limited evidence of carcinogenicity in humans; or sufficient evidence of carcinogenicity in experimental animals)

25. Carcinogens ACGIH A1 confirmed human carcinogen4
Carcinogens
H & S Hazards
(e)(3)(viii)
ACGIH
A1 confirmed human carcinogen
A2 suspected human carcinogen
A3 animal carcinogen
A4 not classifiable as a human carcinogen
A5 not suspected as a human carcinogen
American Conference of Governmental Industrial Hygienists

26. Select Carcinogens 4 H & S Hazards
(e)(3)(viii)
H & S Hazards
Select carcinogen means any substance which meets one of the following criteria:
It is regulated by OSHA as a carcinogen
It is listed under the category, "known to be carcinogens," in the latest NTP RoC
It is listed under Group 1 ("carcinogenic to humans") by IARC
It is listed in either Group 2A or 2B by IARC or under the category, "reasonably anticipated to be carcinogens" by NTP
1. "Carcinogen:" A chemical is considered to be a carcinogen if:
(a) It has been evaluated by the International Agency for Research on Cancer (IARC), and found to be a carcinogen or potential carcinogen; or
(b) It is listed as a carcinogen or potential carcinogen in the Annual Report on Carcinogens published by the National Toxicology Program (NTP) (latest edition); or,
(c) It is regulated by OSHA as a carcinogen.
(e)(3)(viii)(A) Establishment of a designated area; (e)(3)(viii)(B) Use of containment devices such as fume hoods or glove boxes; (e)(3)(viii)(C) Procedures for safe removal of contaminated waste; and (e)(3)(viii)(D) Decontamination procedures.

27. H & S Hazards Initial Monitoring4
H & S Hazards Initial Monitoring
(d)(1)
“Initial monitoring. The employer shall measure the employee's exposure to any substance regulated by a standard which requires monitoring if there is reason to believe that exposure levels for that substance routinely exceed the action level (or in the absence of an action level, the PEL).”
NOTE: NC PELs supersede the Federal ones
Permissible exposure limits. For laboratory uses of OSHA regulated substances, the employer shall assure that laboratory employees' exposures to such substances do not exceed the permissible exposure limits specified in 29 CFR part 1910, subpart Z.

28. H & S Hazards Initial Monitoring4
H & S Hazards Initial Monitoring
The university has a list of 11 chemicals that require initial monitoring before use.
These are only a few of the chemicals that OSHA requires initial monitoring on.
Lawrence Livermore National Laboratory carcinogen list
(d)(1) Initial monitoring. The employer shall measure the employee's exposure to any substance regulated by a standard which requires monitoring if there is reason to believe that exposure levels for that substance routinely exceed the action level (or in the absence of an action level, the PEL).
You should be familiar with the lists.
The Lawrence Livermore National Laboratory carcinogen list is very comprehensive. It compares the ratings and PELs from all agencies on a large number of chemicals.

29. Other Materials are Considered by OSHA to be Physical Hazards4
(e)(3)(viii)
H & S Hazards Other
Other Materials are Considered by OSHA to be Physical Hazards
“Physical hazard means a chemical for which there is scientifically valid evidence that it is a combustible liquid, a compressed gas, explosive, flammable, an organic peroxide, an oxidizer pyrophoric, unstable (reactive) or water-reactive.”
Gas cylinders
Pyrophoric" means a chemical that will ignite spontaneously in air at a temperature of 130 deg. F (54.4 deg. C) or below.
Cryogenic substances?
You have a chart in Section 4 that lists both physical and health hazards

30. Time-Sensitive Chemicals4
Health & Safety Hazards
Time-Sensitive Chemicals
There is no specific regulation to these other than the “hazardous chemical” designation.

31. H & S Hazards Time-Sensitive Chemicals4
H & S Hazards Time-Sensitive Chemicals
Peroxide formers
Peroxide formers that can undergo hazardous polymerization
Materials that become shock or friction sensitive upon the evaporation of a stabilizer
Materials that generate significant additional hazards by undergoing slow chemical reactions
You have some of the information from this site in the packet
DOE

32. Berkeley Peroxide Storage4
H & S Hazards Time-Sensitive Chemicals
Berkeley Peroxide Storage

33. Pre-Purchase Review of Products5
Pre-Purchase Review of Products

34. 5
Before Ordering…
Determine the least amount of material that will suffice, and order that amount - even if the initial cost is higher
Determine if a less hazardous material would could be substituted
Determine if a colleague already has the material in house, and will share

35. Detection of Release or Presence of Hazardous Chemicals6
Detection of Release or Presence of Hazardous Chemicals

36. 6
(f)(4)(i)(A)
“Methods and observations that may be used to detect the presence or release of a hazardous chemical (such as monitoring conducted by the employer, continuous monitoring devices, visual appearance or odor of hazardous chemicals when being released, etc.);”

37. 6
Spills (f)(4)(i)(A)
Considered “Major” or “Minor” by university
A “Major” spill, would be considered one that you could not contain by yourself
Keep a spill kit in the laboratory. The organic labs have chemical specific kits
There is more information at:
The detailed information document has suggested items for the kit.
Chemical Spills

38. Personal Protective Equipment7
Personal Protective Equipment

39. 7
PPE
(f)(4)(i)(C)
“The measures employees can take to protect themselves from these hazards, including specific procedures the employer has implemented to protect employees from exposure to hazardous chemicals, such as appropriate work practices, emergency procedures, and personal protective equipment to be used.”

40. PPE Goggle regulations for laboratories are included in the packet7
PPE
(f)(4)(i)(C)
Goggle regulations for laboratories are included in the packet
Links to proper glove type based on chemical class are included in the packet
The official position on respirators is: avoid using them by using engineering controls (hoods). If you require a dust mask or respirator, you MUST undergo training with the Industrial Hygienist.

41. Emergency Response Plan8
Emergency Response Plan

42. Emergency Response Plan8
29 CFR
Appendix A, D 9a.
a) A written emergency plan should be established and communicated to all personnel; it should include procedures for ventilation failure (200), evacuation, medical care, reporting, and drills (172).

43. Emergency Response Plan8
Emergency Response Plan
The University ERP
“The priorities for emergency response are life safety, property protection and preservation of academic programs.”
The university ERP deals with major disaster responses and the protocols for such
You should read and familiarize yourself with the details of this plan

44. Emergency Response Plan8
The Departmental ERP
“Faculty or staff of the A.R. Smith Department of Chemistry who observe any emergency or disaster in the classrooms, instructional laboratories, research laboratories, or chemical storeroom facilities operated by the department will immediately report this incident to University Police by dialing Ext and giving details of the nature, location, and extent of the incident.”
The departmental chair is the primary contact for us.

45. Material Safety Data Sheets9
MSDSs
Material Safety Data Sheets

46. MSDSs 9
OSHA Standard 29 CFR (h)(1)(ii)
“Employers shall maintain any material safety data sheets that are received with incoming shipments of hazardous chemicals, and ensure that they are readily accessible to laboratory employees.”

47. But, do I need an MSDS for every chemical?9
MSDSs
OSHA Standard 29 CFR (h)(1)(ii)
But, do I need an MSDS for every chemical?

48. Appalachian Safety Office - MSDS9
MSDSs
OSHA Standard 29 CFR (h)(1)(ii)
Is the chemical a general household or office product? Yes____ No____
Is the chemical being used for its intended purpose? Yes____ No____
Is the chemical used in small quantities? Yes____ No____
Is the chemical’s use incidental to your work
(used infrequently and for short periods of time)?
Yes____ No____
Yes.
All persons in charge of teaching laboratory courses should have the MSDS available for each chemical used in the experiments performed.
Appalachian Safety Office - MSDS

49. Okay, but do I have to have a hard copy of each MSDS on hand?9
MSDSs
OSHA Standard 29 CFR (h)(1)(ii)
Okay, but do I have to have a hard copy of each MSDS on hand?

50. MSDSs 9
OSHA Standard 29 CFR (h)(1)(ii)
Refer to the standard – “…ensure that they are readily accessible to laboratory employees.”
If you are going to maintain MSDSs electronically, you must guarantee that anyone working in your lab…

51. Have access to a computer The computer system is always available9
MSDSs
OSHA Standard 29 CFR (h)(1)(ii)
Have access to a computer
The computer system is always available
Because it is not possible to guarantee the system, ASU recommends maintaining a hard copy of of all MSDSs.

52. What about new chemicals that are developed in my lab?9
MSDSs
OSHA Standard 29 CFR (h)(2)
What about new chemicals that are developed in my lab?

53. MSDSs 9 OSHA Standard 29 CFR 1910-1450 (h)(2)
(h)(2)(i) If the composition of the chemical substance which is produced exclusively for the laboratory's use is known, the employer shall determine if it is a hazardous chemical as defined in paragraph (b) of this section. If the chemical is determined to be hazardous, the employer shall provide appropriate training as required under paragraph (f) of this section.
(h)(2)(ii) If the chemical produced is a byproduct whose composition is not known, the employer shall assume that the substance is hazardous and shall implement paragraph (e) of this section.
Paragraph (b) – Definitions of chemical classes and hazards
Paragraph (f) – Employee information and training
Paragraph (e) – CHP
29 CFR “The-Right-To-Know Law”
(h)(2)(ii) If the chemical substance is produced for another user outside of the laboratory, the employer shall comply with the Hazard Communication Standard (29 CFR ) including the requirements for preparation of material safety data sheets and labeling.

54. What information must be on the MSDS?9
MSDSs
OSHA Standard 29 CFR (h)(1)(ii)
What information must be on the MSDS?

55. MSDSs 9 Chemical Identity
OSHA Standard 29 CFR (h)(1)(ii)
Chemical Identity
Section I: Manufacturer’s Name, Contact Information, Date Prepared
Section II: Hazardous Ingredients/Identity Information
Section III: Physical/Chemical Characteristics
Section IV: Fire and Explosion Hazard Data
Section V: Reactivity Data
Section VI: Health Hazard Data
Section VII: Precautions for Safe Handling and Use
Section VIII: Control Measures

56. MSDSs 9 OSHA Standard 29 CFR 1910-1450 (h)(1)(ii) Section 1 No Date?
Useful for ordering or research
Chemical Identity
The identity of the substance as it appears on the label.
Section I. Manufacturer's Name and Contact Information
Manufacturer's name, address, telephone number and emergency telephone number. Date the MSDS was prepared and an optional signature of the preparer.
Section II. Hazardous Ingredients/Identity Information
Lists the hazardous components by chemical identity and other common names. Includes OSHA PEL (Permissible Exposure Limit), ACGIH TLV® (Threshold Level Value) and other recommended exposure limits. Percentage listings of the hazardous components is optional.
VI. Health Hazard Data
Routes of entry (inhalation, skin, ingestion), health hazards (acute = immediate and chronic = build up over time), carcinogenicity (NTP, IARC monographs, OSHA regulated), signs and symptoms of exposure, medical conditions generally aggravated by exposure, emergency and first aid procedures.
Section 6?

57. OSHA Standard 29 CFR 1910-1450 (h)(1)(ii)
MSDSs
OSHA Standard 29 CFR (h)(1)(ii)
Section 6?
This will tell you what class flammable
Section IV. Fire and Explosion Hazard Data
Flash point (and method used to determine it), flammability limits, extinguishing media, special firefighting procedures, unusual fire and explosion hazards.
VII. Precautions for Safe Handling and Use
Steps to be taken in case material is released or spilled, waste disposal method, precautions to be taken in handling or storage, other precautions.
VI. Health Hazard Data
Routes of entry (inhalation, skin, ingestion), health hazards (acute = immediate and chronic = build up over time), carcinogenicity (NTP, IARC monographs, OSHA regulated), signs and symptoms of exposure, medical conditions generally aggravated by exposure, emergency and first aid procedures.
Section 4?
Section 7?

58. OSHA Standard 29 CFR 1910-1450 (h)(1)(ii)
MSDSs
OSHA Standard 29 CFR (h)(1)(ii)
Section 7
Section 8
VII. Precautions for Safe Handling and Use
Steps to be taken in case material is released or spilled, waste disposal method, precautions to be taken in handling or storage, other precautions.
Section III. Physical/Chemical Characteristics
Boiling point, vapor pressure, vapor density, specific gravity, melting point, evaporation rate, solubility in water, physical appearance and odor.
VIII. Control Measures
Respiratory protection (specify type [see respirators), ventilation (local, mechanical exhaust, special or other), protective gloves, eye protection, other protective clothing or equipment, work/hygienic practices.
Section 3?
This information might be useful in an accidental release

59. OSHA Standard 29 CFR 1910-1450 (h)(1)(ii)
MSDSs
OSHA Standard 29 CFR (h)(1)(ii)
Section 5?
This would help with labeling and storage.
You will know if it is a time-sensitive material.
LD50s
Waste & spills
Section V. Reactivity Data
Stability, conditions to avoid, incompatibility (materials to avoid), hazardous decomposition or byproducts, hazardous polymerization (and conditions to avoid).
Oh, here’s the date!
MSDS Demystifier

60. 10
Labeling & Inventory

61. Time-Sensitive Chemicals
Labels 10
Time-Sensitive Chemicals
There is no specific regulation on these, but… the industry standard is -
The full chemical name
Date received
Date opened
Date of decision
Peroxide level
Every source that I found on this suggested this type of label

62. Label Systems ANSI - American National Standards Institute10
ANSI - American National Standards Institute
NFPA - National Fire Protection Association
HMIS - Hazardous Materials Identification System
HMIG - Hazardous Materials Identification Guide
DOT - Department of Transportation

63. Labels & Signs 10 ANSI Standard Z535.4-1998
DANGER indicates an imminently hazardous situation which, if not avoided, will result in death or serious injury. This signal word is to be limited to the most extreme situations.
WARNING indicates a potentially hazardous situation which, if not avoided, could result in death or serious injury.
CAUTION indicates a potentially hazardous situation which, if not avoided, may result in minor or moderate injury. It may also be used to alert against unsafe practices.

64. NFPA DIAMOND 10 Flammability Hazard Health Hazard Reactivity Hazard
Hazard Rating
Severe
Serious
Dangerous
Minor
0 Slight
Special Hazard

65. The Hazardous Materials Identification System, HMIS®10
developed by the National Paint & Coatings Association (NPCA)
At first glance, the HMIS® and NFPA labeling systems appear quite similar. Both have four sections colored blue, red, yellow and white. HMIS® uses colored bars, while NFPA uses colored diamonds. HMIS® attempts to convey full health warning information to all employees while NFPA is meant primarily for fire fighters and other emergency responders. Key point: HMIS® is not intended for emergency circumstances.
OLD
NEW
HMIS® III
HMIS System

66. Hazardous Material Identification Guide - HMIG10
Hazardous Material Identification Guide - HMIG
System developed by Lab Safety Supply, Inc.
HMIG is based on type of PPE that should be used when working with the chemical
HMIG System
A significant difference between the HMIG and HMIS systems is that the recently (1995) revised HMIS system now includes a second box on the blue (health hazard) bar. If this second box holds an asterisk (*), then the health hazard associated with the material is a chronic (long-term) effect.

67. 10
DOT Label Codes
“The Hazardous Materials Transportation Act of 1975 (HMTA), is the major transportation-related statute affecting transportation of hazardous cargoes.”
DOT Codes

68. OSHA Labeling Standard
Labels 10
OSHA Standard 29 CFR (h)(1)(i)
“Employers shall ensure that labels on incoming containers of hazardous chemicals are not removed or defaced.”
OSHA Labeling Standard

69. Labels Secondary Containers That being said… The full chemical name10
OSHA Standard 29 CFR (h)(1)(i)
Secondary Containers
All that is required under the Laboratory Safety Standard
The full chemical name
The date of preparation
Concentration
That being said…

70. OSHA Standard 29 CFR 1910-1450 (h)(1)(i)
Labels 10
OSHA Standard 29 CFR (h)(1)(i)
RTK Labels
ANSI Z129.1: American National Standard for Hazardous Industrial Chemicals - Precautionary Labeling and ANSI Z535.4
OSHA's Hazard Communication Standard (HCS), at 29 CFR (f)(5) states "... the employer shall ensure that each container of hazardous chemicals in the work place is labeled, tagged or marked with... (i) Identity of the hazardous chemicals...and (ii) Appropriate hazard warnings, or alternatively, words, pictures, symbols or combination thereof,...to...provide the employees with the specific information regarding the physical and health hazards of the hazardous chemicals."
All of the sites that I have seen adhere to the HazCom labeling of secondary containers.
This is very important really for the the stockroom.

71. 10
Inventory
Make sure that there is a current inventory available for your research lab
The standard format is a Microsoft Excel Spreadsheet
Information should include full chemical name, formula, physical form, CAS # and NFPA information ( amount present in area would also be useful information)
Not mandated by OSHA, but evidently it is regulated by NFPA as we were sited for this.

72. Inventory Segregate incompatible chemicals10
Segregate incompatible chemicals
General storage should never be alphabetical
Never store chemical on the floor

73. Location of First Aid Supplies and Accident Reports11
Location of First Aid Supplies and Accident Reports

74. 11
First Aid Supplies
There is an assortment of first aid supplies in the Stockroom. They are in a drawer in Section 200.
Some of the teaching labs also have first aid kits
More information on kit contents can be found at the ASU Safety Office

75. 11
EMPLOYEES RESPONSIBILITY IN THE EVENT OF A JOB-RELATED INJURY OR ILLNESS
Report all injuries or illness to your supervisor immediately
Seek appropriate medical attention from the following authorized primary care physicians:
ASU Student Health Services
Watauga Medical Center Emergency Room
Contact Watauga Medics at for emergency transportation to Watauga Medical Center Emergency Room. For non-emergency transportation to ASU Student Health Services or Watauga Medical Center Emergency Room, contact University Police at ext or 2150.
NOTE: In case of a life-threatening emergency, go to the nearest medical facility.
Send the MSDS with the patient.
ASU Safety Office

76. Accident Reports “Accident records should be written and retained”11
Accident Reports
App A
7 (a)
“Accident records should
be written and retained”
There is a short form for non-work related injuries in the manual
All injuries should be reported and a report filled out
National Research Council
Recommendations Concerning Chemical Hygiene in Laboratories (Non-Mandatory)
Even if there is no first aid you should fill out one of these.

77. Fire Extinguisher Use & Flammable Hazards12

78. IFC (2000) NFPA 30 (2000) NFPA 45 (2000) OSHA 29 CFR 1910.10612
Flammable Liquids
IFC (2000)
NFPA 30 (2000)
NFPA 45 (2000)
OSHA 29 CFR

79. OSHA 12 200 Flash Point °F 140 100 73 100 Examples
Standard 29 CFR
200
Flash Point °F
Class IIIA
Class II
COMBUSTIBLE
(Flash Point > 100 °F)
Class IC
FLAMMABLE
Class IA
Class IB
(Flash Point < 100 °F)
140
100 73
Flashpoint" means the minimum temperature at which a liquid gives off vapor within a test vessel in sufficient concentration to form an ignitable mixture with air near the surface of the liquid
100
Boiling Point °F
Examples

80. NFPA DIAMOND 12 NFPA 30 (2000) Flammability Hazard
4 Danger Flammable gas or extremely flammable liquid (Class IA liquids)
3 Warning Flammable liquid flash point below 100° F (Class IA; IB; or IC)
2 Caution Combustible liquid flash point of 100° to 200° F (Class II; or IIIA)
1 Combustible if heated
0 Not combustible

81. Flammable Liquid Storage12
Flammable Liquid Storage
Refer to OSHA Standard (d)(2)(iii)(a)(2) – Table H-12.
(d)(3) -- Design, construction, and capacity of storage cabinets (i) -- Maximum capacity. Not more than 60 gallons of Class I or Class II liquids, nor more than 120 gallons of Class III liquids may be stored in a storage cabinet.

82. 12
Fire Emergencies
We are now allowed to use fire extinguishers without formal training. There is a handout in your manual
The official evacuation distance from the building during a fire drill or actual emergency is 50 feet.

83. Hazardous Waste Procedures13
Hazardous Waste Procedures
EPA 40 CFR

84. Labeling of Waste “Hazardous Waste” Contents as chemical names13
Labeling of Waste
EPA 40 CFR
“Hazardous Waste”
Contents as chemical names
Start date of accumulation
PI name and room number
The approximant amount (%) of each chemical is also helpful
Segregate incompatible chemicals
The NC EPA manual is on the M drive.

85. Chemistry Stockroom Procedures & Use14
Chemistry Stockroom Procedures & Use

86. 14
Stockroom Use
General storage chemicals must be checked out from the stockroom. There is a sign out book by the back door. Indicate what room the chemical is moving to, and how long it will be there. If indefinite, notify the stockroom manager.
If you use up all of a general storage chemical, notify the stockroom manager.
Do not remove equipment from the stockroom without notifying the stockroom manager.
Chemicals prepared in the stockroom should be labeled according to 29 CFR (HAZCOM)

87. 15
Safety Contact Information
Contained in packet. Please familiarize yourself with it.
Post in a conspicuous place.

89. Things To Improve

90. Complete individual inventories
Decide as a department on a uniform labeling system
Test time-sensitive chemicals
Remove all time-sensitive chemicals that are out of date
Test eyewashes and showers
Gather MSDSs for all chemicals used in teaching labs

91. 2. Chemical Procurement, Distribution, and Storage
29 CFR Appendix A, D 2a.
2. Chemical Procurement, Distribution, and Storage
(a) Procurement. Before a substance is received, information on proper handling, storage, and disposal should be known to those who will be involved (215, 216). No container should be accepted without an adequate identifying label (216). Preferably, all substances should be received in a central location (216).

92. 29 CFR Appendix A, D 3b.
(b) Inspections. Formal housekeeping and chemical hygiene inspections should be held at least quarterly (6, 21) for units which have frequent personnel changes and semiannually for others; informal inspections should be continual (21).

93. 29 CFR Appendix A, D 8a.
8.Prominent signs and labels of the following types should be posted:
(a) Emergency telephone numbers of emergency personnel/facilities, supervisors, and laboratory workers (28);

94. 29 CFR Appendix A, D 11c.
(c) Discarding Chemical Stocks: Unlabeled containers of chemicals and solutions should undergo prompt disposal; if partially used, they should not be opened (24, 27).
Before a worker's employment in the laboratory ends, chemicals for which that person was responsible should be discarded or returned to storage (226).