1. Shining a Spotlight on the
Vitamins in Motion
Shining a Spotlight on the
Power of Vitamins

2. About the Campaign
The Vitamins in Motion campaign is an initiative to raise awareness and advocate for increased access, through innovative solutions, to the essential vitamins all people need to be healthy and well-nourished
DSM, a global leader in health and nutrition science, and Sight and Life, a humanitarian nutrition think tank of DSM, are leading an initiative – Vitamins in Motion – to highlight the critical role vitamins play in overall nutrition and health. The campaign advocates for increased access, through innovative solutions, to the essential vitamins all people need to be healthy and well nourished.
Vitamins in Motion aims to shine a spotlight on the power of vitamins in unlocking human potential so that everyone, everywhere is able to contribute to a shared, prosperous future.

3. Nutrition Needs for a Healthy Life

4. Why Vitamins
Vitamins play a critical role throughout the lifecycle for good health and disease prevention
Vitamins and minerals – micronutrients – play a critical role throughout the lifecycle, and are essential for good health in every stage of human life.
Our bodies need vitamins – whether through diet, vitamin supplements or fortified foods – to grow, function, stay healthy and prevent disease.
Humans don’t produce enough vitamins on our own, so we need to get them from our diet, or through supplementation or food fortification.

5. What Should We Expect from our Food?
Vitamins
Vitamin A
Vitamin E Vitamin C
Vitamin D
Vitamin B1
Vitamin B2
Vitamin B6 Vitamin B12 …
Omegas
DHA
EPA
ARA
Carotenoids
B-carotene
Lutein
Zeaxanthin
Enzymes
Phytase
Minerals
Calcium
Magnesium
Iron
Zinc
Iodine
Selenium
Amino acids
Methionine
Lysine
Fibers
Each of the 13 vitamins known today has specific functions in the body, making each vitamin unique and irreplaceable.
Vitamins are essential for normal growth, healthy functioning of the immune system, healthy babies, optimal performance, healthy aging, normal brain growth and good health and appearance.
Carotenoids act as antioxidants to help form the body’s defenses, lowering the risk of certain cancers, such as lung, stomach, cervical, breast, bladder and oral cancers. Other health benefits include protection against heart disease, cataracts and age-related macular degeneration.
Enzymes function as catalysts, speeding up the rate at which metabolic processes and reactions occur in living organisms.
Omega-3 fatty acids reduce inflammation throughout the body, keep blood from clotting, prevent excessive blood clotting, prevent thickening of the arteries, reduce the risk of becoming obese and help prevent cancer cell growth.
Fiber acts as a natural laxative, can act as a prebiotic – feeding healthy bacteria in your gut and increasing colon health, improves blood sugar control and adds bulk to your diet without adding calories.
Minerals are an essential component to a healthy diet – playing unique roles to optimize the health of cells, tissues, organs and the whole being. People who have healthy levels of minerals in their diet are less likely to experience osteoporosis, heart disease, cancer, arthritis, goiter, gastrointestinal disorders, periodontal disease and anemia.
Amino Acids are a key element of building protein in the body, and play a major role in physiological processes relating to our energy, recovery, mood, brain function, muscle and strength gains and fat loss.

6. Micronutrient Deficiencies and Insufficiencies: A Snapshot of Global Micronutrient Status

7. Micronutrient Deficiencies: Global Snapshot
Despite our knowledge of the essential role vitamins play in healthy growth and development, vitamin deficiencies exist in all parts of the world.
Nearly two billion people worldwide cannot access or afford enough nutritious food, and therefore live with a chronic shortage of vital micronutrients – a condition known as hidden hunger.
Undernutrition is responsible for nearly half (45%) of all child deaths under age 5 – representing more than 3 million deaths each year.

8. Micronutrient Deficiencies : Impact on Children
Worldwide, 165 million children are stunted
An estimated 80% of stunted children live in just 14 countries
Malnourished children:
Never reach their full height or cognitive potential
Are less able to fight diseases such as malaria, TB and pneumonia
Do worse in school
Earn at least 20% less as adults
Are at higher risk of chronic diseases later in life
The signs of vitamin deficiencies are not always visible – hence the name “hidden hunger”; they include birth defects, anemia, blindness, impaired physical and mental growth, maternal and child death, brittle bones and increased susceptibility to disease.
Micronutrient deficiencies prevent children from reaching their full potential as adults; malnutrition, especially during the 1,000 days between pregnancy and a child’s second birthday, can lead to largely irreversible physical stunting and cognitive impairment.
Globally, one in four children under age 5 are stunted, totaling 165 million.
Vitamin A deficiency compromises the immune system of approximately 40% of the developing world’s children under the age of 5, and is attributable to the deaths of 670,000 children annually. This is preventable through proven interventions like twice-annual doses of vitamin A supplements for children under age 5.
A child who is severely underweight is 9.5 times more likely to die of diarrhea than a child who is not, and for stunted children the risk of death is 4.6 times higher.
Iron, vitamin A and zinc deficiencies lead to diseases that are among the top 10 causes of death in developing countries.

9. Micronutrient Insufficiencies: Affecting the Wealthiest Countries
United States
Germany
How can vitamin intake inadequacies exist in such wealthy countries? Shifting patterns of diet and lifestyle are leading to poor nutrition, while caloric imbalance contributes to rising rates of obesity and costly non-communicable diseases like diabetes, stroke and heart disease.
Growing evidence from the U.S., Canada, Germany, France, Great Britain and many other countries shows that as many as three-quarters of the populations in these countries are not getting enough key vitamins.
For example, the study above shows that for vitamins A, D and E, more then 75% of both men and women in the United States do not get enough of these vital micronutrients.
The prevalence of inadequate vitamin E intake is actually 90% among Americans.
Less-than-optimal vitamin intake can have a wide range of impacts on health and wellbeing. Type I and II diabetes, hypertension, stroke, heart attack and heart failure, multiple sclerosis, depression and Alzheimer’s are all potentially associated with inadequate vitamin D intake.
Increasingly, vitamin D deficiency is being recognized as a serious public health issue; one in three women and one in five men over 50 will experience osteoporotic fractures linked to inadequate vitamin D intake.
Average folate intake in the U.S., Canada, UK, Europe, Australia, New Zealand and Japan are between 13% and 63% lower than recommendations, and iron intakes are below nutrient recommendations in all developed regions.
About one-third of U.S. diabetics and half of European diabetics carry a certain genetic variant that may have increased risk of heart disease. But a vitamin E supplement of 400 IU/day may reduce their risk to almost the same level as individuals without this genetic variant.
Recent research shows that a high dose of vitamin E can reduce the progression of mild and moderate Alzheimer’s disease by 19%, and delay progression of the disease by 6.2 months.
Proper vitamin D intake could reduce bone fractures by 28%.

10. Micronutrient Deficiencies and Insufficiencies: Health Impact

11. Micronutrient Deficiencies/Insufficiencies: The Impact in Numbers
children go blind or die
each year from
vitamin A deficiency
1.1 million
600,000
stillbirths due to
iron deficiency
18 million
babies born mentally
impaired due to maternal
iodine deficiency
of world population
estimated to be
vitamin D deficient
40-75%
200 million
people estimated to
be living with
osteoporosis worldwide
200 million
Poor nutrition and micronutrient deficiency have a staggeringly large impact. They:
Impair the mental development of up to 60% of infants in the developing world;
Debilitate the health of 500 million women across the globe; and
Lead to more than 60,000 deaths during childbirth every year.
Iodine deficiency is the leading preventable cause of brain damage, resulting on average to a loss of IQ points.
Zinc deficiency contributes to 116,000 deaths each year for children between 1-5 years.
Almost half of all children in low- and middle-income countries (47%) are affected by anemia, and 42% of pregnant women – 56 million – suffer from anemia.
deaths due to non-communicable diseases

12. Micronutrient Deficiencies/Insufficiencies: Link to Non-Communicable Diseases
36 of the 57 million global deaths in 2008 were due to NCDs
Worldwide:
366 million people have diabetes
200 million people have osteoporosis
1.6 billion people are overweight
80% of premature heart disease, stroke & diabetes can be prevented
Diet is an important modifiable factor
Less-than-optimal vitamin intake can have a wide range of impacts on health and wellbeing.
According to a WHO 2010 report on non-communicable diseases (NCDs), 36 million of the 57 million global deaths in 2008 were due to NCDs. And 29% of NCD deaths in low- and middle-income populations in 2008 occurred before the age of 60.
Globally, one in three adults was overweight or obese in 2008, an increase of 23% since In the developing world, the number of overweight or obese adults has more than tripled from 250 million to 904 million.
Compared to two decades ago, there are 54% more overweight children, and an estimated 43 million children under 5 are overweight. In 2011, 69% of the global burden of overweight children under 5 was in low- and middle-income countries.
The effects on the health and wellbeing of individuals are staggering – and have resulted in increased rates of diabetes, osteoporosis, overweight, heart disease, stroke and diabetes in developing countries across the globe.
Diet is an important modifiable factor that can help prevent the onset of NCDs.

13. Longer, Healthier Lives
The Power of Micronutrients Throughout Life
Longer, Healthier Lives
Lower risk of dementia
Lower risk of age-related macular degeneration
Delayed progression of Alzheimer’s
Seniors
Staying Healthy
Prevention of diabetes, heart disease and stroke
Multivitamins, along with a balanced diet, have the potential to reduce the risk of cancer by 8-12%
Adults
Optimal Development
Power to fight off diseases
Lower risk of chronic diseases
Higher achievements in school
Increased productivity as adults
Infants & Toddlers
Pre-natal Health
Iron ensures healthy deliveries and improves birthweight of babies
Folate helps prevent neural tube defects in babies
Pregnancy
Micronutrients ensure proper health and development from pregnancy through infancy and childhood and into adulthood and old age.
Iron and folate supplements are crucial for expecting mothers. They:
Ensure healthy deliveries and improve the birthweight of babies; and
Prevent neural tube defects in babies.
Proper nutrition during the 1,000 days between pregnancy and a child’s second birthday:
Staves off diseases like pneumonia and malaria;
Reduces the risk of chronic diseases;
Increases performance levels in education; and
Increases productivity as adults.
When children are properly nourished throughout life and into adulthood, they:
Have lower rates of noncommunicable diseases; and
Have lower rates of cancer.
A lifetime of proper health and nutrition ensures:
Reduced cognitive decline in seniors;
Lower risk of dementia; and
Lower risk of age-related macular degeneration.
Multivitamins, along with a balanced diet, have the potential to reduce the risk of cancer by 8-12%.

14. Micronutrient Deficiencies and Insufficiencies: Economic Impact

15. Micronutrient Deficiencies:
Impact on Economic Growth
In addition to being a public health crisis, micronutrient deficiencies have a real impact on economic development, lowering the productivity of individuals and entire populations, seriously hindering the potential of entire countries.
It has been estimated that undernutrition reduces a nation’s economic advancement by at least 8% due to direct productivity losses, losses via poorer cognition and losses via required schooling.
In 2012, the Copenhagen Consensus expert panel found that providing micronutrients to children is the single smartest way to spend global aid dollars, with every $1 spent yielding $30 in benefits.
In total, current childhood malnutrition could cost the global economy $125 billion when today’s children reach working age in 2030.
Compared with non-stunted children, stunted children:
Score 7% lower on math tests;
Are 19% less likely to be able to read a simple sentence by age 8, and 12% less likely to be able to write a simple sentence; and
Are 13% less likely to be in the appropriate grade for their age at school.
Children who are malnourished go on to earn 20% less as adults than the children who are well nourished.
Fixing malnutrition now could bring economc benefits over 100 times as large as the costs of interventions.
Undernutrition can reduce a nation’s economic advancement by at least 8 percent
Every $1 invested in micronutrient interventions yields $30 in benefits

16. Micronutrient Insufficiencies:
Impact on Health Care Costs
Micronutrient insufficiencies increase the risk of diseases from diarrhea to diabetes, which place tremendous strain on health care systems and economies
Vitamin D insufficiency costs 17 European countries €187 billion in direct and indirect health care costs each year
Not only does insufficient vitamin intake negatively affects the health and wellbeing of entire populations, it also places tremendous strain on health care systems and economies. A recent study by Grant et al found that vitamin D insufficiency costs 17 European countries €187 billion in direct and indirect health care costs each year.

17. Putting Vitamins in Motion

18. Conducting cutting-edge research
Nutrition Solutions:
Putting Vitamins in Motion
Conducting cutting-edge research
Forging partnerships
Convening key stakeholders
Raising awareness 1 2 3 4
Research shows that micronutrient interventions like vitamin supplementation and food fortification improve health, save lives and increase productivity.
Micronutrient interventions are key to solving our global nutritional challenges and breaking the cycle of poverty. We must increase access to and scale up these cost-effective solutions, and continue to invest in the vitamin science that is uncovering innovative ways to nourish children, build strong families and create vibrant communities.
DSM and Sight and Life have a long history of combating micronutrient deficiencies around the world, and are committed to putting Vitamins in Motion. To us, this means:
We conduct cutting-edge research in vitamin science to uncover innovative solutions to address the world’s micronutrient deficiencies with new and improved nutrition products, such as fortified blended foods, micronutrient powder packets and fortified rice.
We forge partnerships with organizations like the UN World Food Programme (WFP), UNICEF, Vitamin Angels, GIZ (German International Development Agency), the International Osteoporosis Foundation and World Vision to advocate for and deliver micronutrients to populations at risk.
We convene key stakeholders to break down silos and seek new solutions in the fight against malnutrition.
We raise awareness of inadequate micronutrient intake in developing and developed countries, and the impact on healthy aging, health care systems and maternal and child health.

19. Conducting Cutting-Edge Research in Vitamin Science
Scientists at DSM developed NutriRice™, which is added to natural rice at a ratio of 1:100, improving the health and productivity of whole populations
Sight and Life has actively advanced research on the use of multiple micronutrient supplements during pregnancy to improve maternal nutrition and newborn outcomes
DSM and Sight and Life are conducting cutting-edge research in vitamin science to uncover innovative solutions to address the world’s micronutrient deficiencies with new and improved nutrition products, such as fortified blended foods, micronutrient powder packets and fortified rice.
Scientists at DSM developed an innovative rice kernel called NutriRice™, which is added to natural rice and provides essential micronutrients. NutriRice™ is now widely used in several developing countries, helping to improve the health and productivity of whole populations.
DSM developed MixMe™, an innovative multi-micronutrient powder that can be added to food without impacting taste. Together with Herbalife, DSM has also recently donated 20 million sachets of MixMe™ as part of the global nutrition campaign, “Future Fortified,” which is helping tackle the hunger crisis in the Horn of Africa.
Sight and Life has actively advanced research on the efficacy and effectiveness of:
Micronutrient powders (MNP) and lipid-based nutrient supplements in infants and young children;
Multiple micronutrient supplements during pregnancy to improve maternal nutrition and newborn outcomes; and
The enzyme phytase that reduces phytic acid that binds iron and zinc, and so improves their absorption.
Sight and Life also contributes to ensuring that the evidence addresses all aspects of micronutrient fortification and supplementation by supporting research that examines any risk of these interventions. In collaboration with the Swiss Federal Research Institute (ETH Zurich) research is examining the effect of iron on the gut microbiota and approaches to improve gut health that is thought to have an important impact on micronutrient status. Sight and Life is also supporting research on biomarkers, with a focus on innovative technologies to facilitate field-friendly kits for the assessment of micronutrient status and monitoring the content of micronutrients in fortified food.

20. Conducting Cutting-Edge Research in Vitamin Science
DSM Engages in Studies on The Role of Nutrients for Health
DO-HEALTH: Vitamin D3, Omega-3, Home Exercise, Healthy Aging and Longevity Trial
Objective: To improve healthy aging in European seniors and reduce health care costs via the implementation of effective and broadly applicable disease prevention interventions
Food4Me: Towards Personalized Nutrition
Objective: To find solutions for how to address individual needs and determine whether dietary advice based on a person’s genes and phenotypical characteristics could deliver consumer benefits
Set-up: 25 partners from universities and industry and 9 countries in Europe
MARRIAGE: University of Groningen
Objective: To determine markers of aging and the role of micronutrients

21. Forging Partnerships with Leaders in Nutrition
As part of the Global Nutrition for Growth Compact, DSM has committed to help provide effective nutrition interventions to 50 million pregnant and lactating women and children under 2 per year by 2020
In partnership with UNICEF, WFP, CDC and the Home Fortification Technical Advisory Group, Sight and Life published ‘Home Fortification with Micronutrient Powders (MNP)’ to inform implementation of home fortification programs globally
DSM and Sight and Life are forging partnerships with organizations like the World Food Programme (WFP), UNICEF, Vitamin Angels, GIZ (German International Development Agency), the International Osteoporosis Foundation and World Vision to advocate for and deliver micronutrients to populations at risk.
DSM recognizes that addressing nutrition is critical to achieving the United Nations Millennium Development Goals. As part of the Global Nutrition for Growth Compact, DSM has committed to help provide effective nutrition interventions to 50 million pregnant and lactating women and children under 2 per year by The company will reach these individuals through ongoing advocacy efforts and using its sphere of influence, as well as through existing public-private partnerships, such as with the World Food Programme, Vitamin Angels and World Vision International.
In partnership with UNICEF, World Food Programme, the US Centers of Disease Control and Prevention and the Home Fortification Technical Advisory Group, Sight and Life recently published the ‘Home Fortification with Micronutrient Powders (MNP)’ manual to inform the implementation of home fortification programs globally. The publication includes case studies and lessons learned pertaining to policy, production, delivery, monitoring and behavior change communication. It also summarizes results from five regional home fortification workshops designing MNP scale-up plans in 66 countries and outlines areas for further research to strengthen the implementation and effectiveness of MNP interventions.

22. Forging Partnerships with Leaders in Nutrition
DSM scientists, in partnership with the International Osteoporosis Society (IOF), developed a global map summarizing the vitamin D status in infants and adults
DSM, jointly with IOF, nutrition experts and scientists all over the world are advocating for optimal vitamin D levels to reduce the risk for osteoporosis
Ref: Wahl DA et al, Archives of Osteoporosis 2012

23. Convening Key Stakeholders
In early 2014, with partners from the World Food Programme and Columbia University, Sight and Life convened key thinkers to start a much-needed discussion on what the post-2015 nutrition workforce needs to look like to ensure adequate, safe and nutritious food for all
In 2013, DSM and Sight and Life convened leaders at the United Nations General Assembly for a reception – Celebrating Leadership in Global Battle to End Undernutrition
DSM and Sight and Life are convening stakeholders to break down silos and seek new solutions in the fight against malnutrition.
DSM and Sight and Life assemble key stakeholders at events such as the World Economic Forum and the United Nations General Assembly, and participate in scientific conferences to share the latest breakthroughs in micronutrient research.
In early 2014, with partners from the UN World Food Programme and Columbia University, Sight and Life convened key thinkers from a diverse range of nutrition and nutrition-related fields in Castel Gandolfo. The purpose for this meeting was to start a much-needed discussion on what the post-2015 nutrition workforce needs to look like it we are to ensure adequate, safe and nutritious foods for all in an environmentally sustainable manner. The discussion focused on key technical, human resource management and leadership competencies.
In 2013, DSM and Sight and Life gathered health and development stakeholders during the UN General Assembly to recognize the vital role of strong leadership in improving nutrition, a precondition to achieving many of the Millennium Development Goals. Lead Lancet Maternal and Child Nutrition Series author Dr. Robert Black and the Maternal and Child Nutrition Study Group received Sight and Life’s Nutrition Leadership Award.
In 2014, DSM and Sight and Life are participating in events such as:
Experimental Biology in San Diego, CA in April
Micronutrient Forum in Addis Ababa, Ethiopia in June
ICN-2 in Rome, Italy in November

24. Convening Key Stakeholders
Analytics Workshop With Key Stakeholders
Kaiseraugst, November 2013
Conference: DSM supports the first International Congress on Hidden Hunger
Germany, 6 – 9 March 2013
DSM Awarded and Rewarded during 2013 CSN Conference
Hangzhou, China, 21 May 2013
DOHaD Conference
Singapore, 19 November 2013
IUNS Meeting
Granada, Spain, 15 – 20 September 2013

25. Raising Awareness of Inadequate Micronutrient Intake
DSM is at the forefront of research efforts to set optimal intake recommendations for vitamin E, a powerful antioxidant that protects cells, tissues and organs from damage
The Sight and Life Hidden Hunger Index and Maps, launched in 2013, for the first time illustrated the combined prevalence, in preschool children, of multiple micronutrient deficiencies – vitamin A, zinc, iron and iodine
DSM and Sight and Life are raising awareness of inadequate micronutrient intake in developing and developed countries, and the impact on healthy aging, health care systems and maternal and child health.
DSM joined forces with the International Osteoporosis Foundation to release an interactive global map of vitamin D intake, confirming that vitamin D insufficiency is a major public health issue worldwide, with more than one-third of all the populations studied showing insufficient levels of vitamin D. DSM called for health care decision-makers to take immediate action to address vitamin D insufficiency as a priority public health issue, and emphasized the role of vitamin supplementation in addressing the problem.
DSM is currently engaged in the largest study in Europe to demonstrate the benefit of vitamin D supplementation in the elderly. DSM is also engaged in an assessment of the impact of vitamin D supplementation on reduced mortality.
DSM is at the forefront of research efforts to set optimal intake recommendations for vitamin E, a powerful antioxidant that protects cells, tissues and organs from damage.
The Sight and Life Hidden Hunger Index and Maps, launched in 2013, for the first time illustrated the combined prevalence, in preschool children, of multiple micronutrient deficiencies – vitamin A, zinc, iron and iodine. This valuable tool helps governments and partners translate nutrition commitments into action through informed policy and program decisions. This Hidden Hunger Index is currently being updated to include changes in hidden hunger over the past two decades.

26. Turning Commitments into Action
We are committed to putting Vitamins in Motion
We have the power to nourish children, build strong families and create vibrant communities
DSM and Sight and Life have a long history of combating micronutrient deficiencies around the world, and are committed to putting vitamins in motion.
We must shine a spotlight on the power of vitamins in unlocking human potential so that we can nourish children, build strong families and create vibrant communities. Only then can everyone, everywhere contribute to a shared, prosperous future.
So everyone, everywhere can contribute to a shared, prosperous future

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28. Thank You