1. RNA & Central Dogma

2. Bellwork- have slate, marker & eraser on desk
What does DNA stand for?
Based on your answer to #1, predict what RNA stands for?
What is the complementary DNA strand to this sequence GTA ATC ATA?
Draw and label a picture of a nucleotide.
Who are Watson & Crick & what do they have to do with DNA?

3. Announcements
Bio 1-2: Is your science fair board turned in? PreAP: BLAST handout get ratHBB from class home DietrichBiology.wikispaces.com due date changed to next Tues Everyone: This is a block week, so Friday is…. Everyone: Pass out slates for today

4. Central Dogma (“Big Idea”) of Biology
DNA stores information to run cell
DNA
RNA
Protein

5. Deoxyribonucleic Acid
DNA vs RNA
How many nucleotides?
3 parts of a nucleotide?
What does the “B” stand for?
Deoxyribonucleic Acid

6. Deoxyribonucleic Acid
DNA vs RNA
What’s the difference?
How many nucleotides?
3 parts of a nucleotide?
What does the “B” stand for?
OH!
Deoxyribonucleic Acid
Ribonucleic
Acid

7. Structure is related to function! What are DNA’s 2 functions?
Remember this?
Structure is related to function!
What are DNA’s 2 functions?

8. RNA Structure Notes
RIBOSE is the sugar in RNA nucleotides (instead of deoxyribose)

9. RNA Structure Notes
RIBOSE is the sugar in RNA nucleotides (instead of deoxyribose)
In RNA, the nitrogenous bases are G,C,A and U (no T)

10. RNA Structure Notes
RIBOSE is the sugar in RNA nucleotides (instead of deoxyribose)
In RNA, the nitrogenous bases are G,C,A and U (no T)
RNA is usually single-stranded

11. Vote by sign language: NA NA
RNA
DNA
DNA
AGCCTGCTA
TCGGACGAT
RNA
RNA

12. Try this AGTTCGA TCAAGCT RNA: UCAAGCU
What might it look like if you turned this double stranded DNA molecule into an RNA copy?
AGTTCGA
TCAAGCT
RNA: UCAAGCU
Which DNA strand would this RNA be the COMPLEMENT of?

13. Try this AGTTCGA TCAAGCT RNA: UCAAGCU AGUUCGA
What might it look like if you turned this double stranded DNA molecule into an RNA copy?
AGTTCGA
TCAAGCT
RNA: UCAAGCU
AGUUCGA
Which DNA strand would this RNA be the COMPLEMENT of?
Do the RNA complement for the bottom DNA strand

14. RNA has a different structure… predict it’s functions (jobs)
DNA vs RNA
RNA has a different structure… predict it’s functions (jobs)
Hint: other names for RNA
messenger RNA
ribosomal RNA
transfer RNA

15. Central Dogma (“Big Idea”) of Biology
DNA stores information to run cell
DNA
RNA’s function is to make proteins!
RNA
Protein

16. Why are proteins so important?
Proteins are made of tiny subunits…what are they called?
What are some functions of proteins? (Hint: )
Chemical Reactions (enzymes)
Immune System (antibodies)
Growth & Development (hormones)
etc.

17. Central Dogma (“Big Idea”) of Biology
DNA stores information to run cell
DNA
RNA’s function is to make proteins!
RNA
Proteins actually DO the work in the cell
Protein

18. Types of RNA
mRNA: messenger RNA makes a copy (message) of the information stored in DNA & moves the info out of the nucleus! (DNA doesn’t leave nucleus)
Codons are 3 letter “words” that make up the message- it’s a recipe for a protein

19. Types of RNA
rRNA: ribosomal RNA folds into a ribosome which reads the mRNA codons and connects amino acids into a chain that will become a protein
Realistic image of rRNA folded into a ribosome
rRNA folds into 2 subunits (large & small)
Together, they make the ribosome!

20. Types of RNA
tRNA: transfer RNA transports amino acids to the ribosome, and uses an anti-codon to match the correct amino acid to the correct mRNA codon. It then transfers amino acids to the growing chain.
tRNA is T-shaped!

21. Closure- Structure & Function of DNA & RNA