1. Human Physiology Physiology 1 Section 3056 – Mon Lab Section 3057 – Wed Lab Dorena Rode drode@santarosa.edu 577-0379 8am – 8pm

2. Course Web Site www.dorenarode.com/physiology Lecture notes Study guide Old tests Study questions Syllabus Links to other resources

3. Web Check In Why?  To get email alerts, updates, and study tips  To take pretest (4 easy extra credit points)  Monitor grades  Upload your student report

4. Course Requirements Attendance at lecture and laboratory 11 quizzes (drop lowest two) 3 midterms Final  Mostly just a fourth midterm  Small section cumulative final Written/Oral Report  Sign ups will be in lab Lab assignments; lab quizzes  More details later

5. How to study for this class Use Chat Room to meet study partners

6. Science in Perspective Everything Truth Physiology How the Body Works Web of Life Whole Picture Complex Whole Scientific Knowledge

7. Science in Perspective Exercise decreases resting heart rate Aspirin decreases heart attacks How the heart beats Other heart related studies Assumptions about heart

8. Scientific Method FOX pg 4-6 1. Observing natural phenomenon 2. Guessing “How” (formulate hypothesis) 3. Design experiment 4. Do experiment 5. Collect/analyze data 6. Draw conclusions

10. Biological Organization

11. cells Basic unit of structure and function in the body

12. tissues Groups of cells with a similar function. muscular nervous epithelial connective

13. organs Anatomical and functional units formed by collections of the four tissue types. Heart Liver Skin

14. systems Collections of organs that perform a common function.

15. systems nervous endocrine musculoskeletal circulatory respiratory urinary digestive immune reproductive integumentary

16. Homeostasis State of dynamic internal constancy. We maintain homeostasis by using negative feedback mechanisms.

17. Essential Parameters heat (measured as temperature) pH oxygen ion concentrations water blood pressure glucose

18. pH regulation What is pH? pH = -log [H + ] As hydronium ion concentration goes up the pH goes down.

19. pH regulation Why do we control pH?  Chemical reactions happen at only certain pH  Proteins are active at certain pH

20. pH regulation How do we control pH? 1.Normal plasma pH = 7.4 2.Bicarbonate buffers small changes in pH 3.We do something and pH drops 4.Change in pH is detected by sensor (aortic and carotid bodies) 5.Signal sent to control center typically either a hormone or nerve impulse 6.pH value compared to set point 7.If outside set point range, then a signal is sent to an effector Effectors are typically a muscle or gland. Once activated the cells react to the stimulus and typically produce either a protein or release vesicles. 8.Effectors involved in pH regulation: pulmonary system, renal system, bones

21. Lab this week:  Lab 1  Lab 2(skip question 5)  Should Bill buy Sammy?