1. 25 Years of AIDS – The Global Response 16 August 2006 XVI International AIDS Conference Toronto

2. Global HIV prevalence in adults, 1985 UNAIDS/WHO, 2006

3. Global HIV prevalence in adults, 1995 UNAIDS/WHO, 2006

4. Global HIV prevalence in adults, 2005 UNAIDS/WHO, 2006

5. 25 years of responding to AIDS First cases of unusual immune deficiency are identified among gay men in the USA, and a new deadly disease noticed The Human Immunodeficiency Virus (HIV) is identified as the cause of AIDS Scientists develop the first treatment regimen to reduce mother-to-child transmission of HIV Brazil becomes the first developing country to provide antiretroviral therapy through its public health system WHO and UNAIDS launch the "3 x 5" initiative with the goal of reaching 3 million people in developing world with antiretroviral therapy by 2005 The first HIV antibody test becomes available In Africa, a heterosexual AIDS epidemic is revealed Highly Active Antiretroviral Treatment launched The World Health Organization launches the Global Programme on AIDS Acquired Immune Deficiency Syndrome (AIDS) is defined for the first time The first therapy for AIDS — zidovudine, or AZT — is approved for use in the USA Global Network of People living with HIV/AIDS (GNP+) (then International Steering Committee of People Living with HIV/AIDS) founded Drug Access Initiative is launched in Africa International AIDS Conference in Durban The Global Fund to fight AIDS, Tuberculosis and Malaria launched The UN General Assembly Special Session on HIV/AIDS In 1991-1993, HIV prevalence in Uganda and in Thailand begins to decrease, the first major downturn in the epidemic in developing countries UNAIDS is created Millions 50 45 40 35 30 25 20 15 10 5 0 1980‘812005‘82‘83‘84‘85‘86‘87‘88‘89‘90‘91‘92‘93‘94‘95‘96‘97‘98‘99‘00‘01‘02‘03‘04 People living with HIV Children orphaned by AIDS in sub-Saharan Africa 2006 Report on the global AIDS epidemic (UNAIDS, 2006) President Bush announces PEPFAR

7. Projet SIDA

8. 25 years of responding to AIDS First cases of unusual immune deficiency are identified among gay men in the USA, and a new deadly disease noticed The Human Immunodeficiency Virus (HIV) is identified as the cause of AIDS Scientists develop the first treatment regimen to reduce mother-to-child transmission of HIV Brazil becomes the first developing country to provide antiretroviral therapy through its public health system WHO and UNAIDS launch the "3 x 5" initiative with the goal of reaching 3 million people in developing world with antiretroviral therapy by 2005 The first HIV antibody test becomes available In Africa, a heterosexual AIDS epidemic is revealed Highly Active Antiretroviral Treatment launched The World Health Organization launches the Global Programme on AIDS Acquired Immune Deficiency Syndrome (AIDS) is defined for the first time The first therapy for AIDS — zidovudine, or AZT — is approved for use in the USA Global Network of People living with HIV/AIDS (GNP+) (then International Steering Committee of People Living with HIV/AIDS) founded Drug Access Initiative is launched in Africa International AIDS Conference in Durban The Global Fund to fight AIDS, Tuberculosis and Malaria launched The UN General Assembly Special Session on HIV/AIDS In 1991-1993, HIV prevalence in Uganda and in Thailand begins to decrease, the first major downturn in the epidemic in developing countries UNAIDS is created Millions 50 45 40 35 30 25 20 15 10 5 0 1980‘812005‘82‘83‘84‘85‘86‘87‘88‘89‘90‘91‘92‘93‘94‘95‘96‘97‘98‘99‘00‘01‘02‘03‘04 People living with HIV Children orphaned by AIDS in sub-Saharan Africa 2006 Report on the global AIDS epidemic (UNAIDS, 2006) President Bush announces PEPFAR

9. Total annual resources available for AIDS 1986 ‒ 2005 0 1000 2000 3000 4000 5000 6000 7000 8000 9000 US$ million 292 1623 8297 Signing of Declaration of Commitment on HIV/AIDS, UNGASS 19961997199819992000200120022003200420051986198719881989199019911992199319941995 Less than US$ 1 million 59 212 World Bank MAP launch Global Fund PEPFAR 257 [i] 1996-2005 data: Extracted from 2006 Report on the global AIDS epidemic (UNAIDS, 2006) [ii] 1986-1993 data: AIDS in the World II. Edited by Jonathan Mann and Daniel J. M. Tarantola (1996) Notes:[1] 1986-2000 figures are for international funds only [2] Domestic funds are included from 2001 onwards UNAIDS

10. HIV prevalence (%) among pregnant women attending antenatal clinics in sub-Saharan countries with prevalence decline, 1997/98 ‒ 2004 2006 Report on the global AIDS epidemic (UNAIDS, 2006) Kenya Zimbabwe Burkina Faso Uganda 1997 ‒ 1998 1999 ‒ 2000 2001200220032004 0 5 10 15 20 Median HIV prevalence (%) 40 35 30 25

11. North Africa and the Middle East Europe and Central Asia East, South and South-East Asia Latin America and the Caribbean Sub-Saharan Africa 0 200 400 600 800 1000 1200 1400 End 2002 Mid- 2003 End 2003 Mid- 2004 End 2004 Mid- 2005 End 2005 People receiving therapy (thousands) Number of people on antiretroviral therapy in low- and middle-income countries, 2002 ‒ 2005 2006 Report on the global AIDS epidemic (UNAIDS, 2006)

12. Planning and acting for success: LeadershipFunding Making the money work Social change: Tackle the structural drivers of the epidemic Research & Development

13. Maintaining the exceptionality of AIDS – but at the core of development agendas not outside