1. Clinical and Translational Science Institute / CTSI at the University of California, San Francisco Clinical Research Services: “The Beat Goes On” CTSI Board of Directors’ Meeting September 5 th, 2012

2. Major Challenges Impacting CRS Nursing salary and benefit expense increases Reduction in CTSA grant support Lack of data for ‘evidence-based’ business decisions Increased administrative expenses to support the recharge model “Grandfathering” needed for faculty buy-in –Liability must be funded but will decrease over time Revenue ramp up will be slow 2

3. Opportunities: Specific Strategies “Low-lying fruit” –Weekend closures SFGH is open one weekend and one Saturday per month only if we have research subjects Moffitt adult and pediatrics close nights/weekends if no research subjects/boarders –SFGH space consolidation Outpatient space returned to hospital June 2012 Outpatient activity moved to office space adjacent to inpatient unit to improve utilization and efficiency –Taking advantage of attrition SFGH, NCRC and administration 3

4. Opportunities: Specific Strategies Planning in progress for “right” sizing inpatient facilities to align with research utilization –Reviewing census and utilization at nursing sites –Analysis of SOC reimbursement/costs –Work with Department of Pediatrics and Medical Center to begin planning transition to Mission Bay Review financial agreements and processes with UCSF Medical Center 4

5. Opportunities: Specific Strategies Expand use of “scatter” staffing model to address fluctuating workload Establish approved campus recharges –Targeting all proposals submitted by 9/1 –Recharge model will ‘right size’ subsidy % –Significantly improves efficiency in budgeting studies 5

6. Opportunities: Specific Strategies Quantify ‘grandfathering’ liability –Best estimate requires grant funding information not currently available to CRS Complete efficiency project for all areas –Will help with identifying specific functionality needed in new tools/systems –Will increase capacity to take on new customers and provide new services 6