1. Antiseptic liquids of TehnoDent Company 2% chlorhexidine digluconate 2% chlorhexidine digluconate 3,0% -5,2% sodium hypochlorite 3,0% -5,2% sodium hypochlorite liquid for orifice detection and expansion of dental root canals on the basis of EDTA salts (20%) liquid for orifice detection and expansion of dental root canals on the basis of EDTA salts (20%)

2. Quality criteria of root canal medicated treatment Thorough diagnosis of existing pulp - periodontal pathology Recording of the dental tissues condition and the complexity of the root canal anatomy system The removal of endodontic smear layer Observance of the indications for choosing the irrigation materials The optimization of irrigating solution active components The correct sequence of application of the irrigation solution during root canal treatment Mandatory costs at least 10 minutes per 1 irrigation of the root canal before filling

3. Microflora of dental root canals Str. Mitis Staph. Epidermalis Str. Mutans R. Pikettii In case of pulpitis Str. Mitis Staph. Epidermalis Str. Mutans Staph. Haemoliticus Str. Faecalis In case of periodontitis

4. Root canals anatomy

5. The root canal system cleansing by chemical dissolution of organic and inorganic residues, as well as their mechanical washout with the stream of liquid. The root canal system disinfection. The aim of root canals irrigation

6. To possess bactericidal effects to the microorganisms associations, existing in root canals Be indifferent to periapical tissues Lack of sensitizing effect on the body Do not induce the emergence of resistant forms of microorganisms To provide fast action and deeply penetrate into dentinal tubules Not to lose effectiveness in the presence of organic materials Not to have an unpleasant taste and smell To clear the channel lumen from organic residues, to facilitate its evacuation from the channel To be chemically stable and remain active during prolonged storage Requirements for antiseptics in endodontics

7. TehnoDent’s chlorhexidine digluconate liquid 2% The optimal antiseptic concentration for effective root canals sterilization The original dosing system Pro Luer allowing to use the drug to the last drop Now it is not necessary to order in the pharmacy Good shelf life, easy storage and transportation

8. ! NB! Antimicrobial activity directly depends on the concentration Chlorhexidine digluconate liquid 2% (+) non-toxic (+) has low allergenicity (+) active against gram-positive and gram-negative bacteria and retains activity in the presence of blood and purulence (+) has prolonged effect (+)(+) (-) does not dissolve organic tissues (-) not effective in respect of smear layer (-)(-)

9. Liquid sodium hypochlorite 3%; 5,2% it has intense bactericidal activity and a strong oxidizing effect inexpensive material with a large enough shelf life, displays a whitening effect in case of change the tooth color increases the permeability of dentinal tubules and is extremely strong antiseptic and a effective solvent of live pulp and necrotic tissue

10. Sodium hypochlorite liquid 3%; 5.2%  It has improved base, increasing the period of use  It has the original dosing system Luer Pro, allowing to use the material till the last drop

11. Properties of sodium hypochlorite liquid Sodium hypochlorite liquid 3%; 5.2% Antimicrobial effect does not depend on concentration Solvent efficiency increases with concentration Heating increases the lytic properties (+)(+) Toxic Not effective against E. faecalis Causes corrosion Has an unpleasant smell Not effective in respect of smear layer (-)(-)

12. Liquid for orifice detection and expansion of dental root canals on the basis of EDTA salts 20% Contains surface-active antiseptic that provides the foaming Has a low index of surface tension - penetrates quickly into the channels and micro canals Easy to use

13. Advantages of EDTA salts Low surface tension of the material, allowing to penetrate into the lumen of the narrow root canal EDTA decalcificates and softens the parietal dentin. The mechanism of action is based on the capture and binding of calcium ions from the dentin, forming a chelate compound After the removal of calcium from the canal, the dentine is softened and is removed more easily that facilitates the sliding of the instrument in the root canal The material is not toxic and has an acidic activity for periapical tissues, and acts optimally within 15 minutes The drug can be used not only to expand the root canal, but also as an antiseptic

14. The interaction of NaOCl + CHX - para-chloroaniline (NaC 6H4Cl) - toxic and cancerigenic compound appears in the process reaction.

15. Interaction of NaOCl + EDTA - decreases the amount of free chlorine, has an antibacterial effect, there is a slow inactivation of NaOCL

16. The interaction of CHX + EDTA – precipitate is formed, its content consists for 90% of chlorhexidine and ЕDTA, the clinical significance of which is unknown, with a probability of less than 1% the chemical dissolution on p-chloroaniline is possible. Do not use sodium hypochlorite after compounding of chlorhexidine and EDTA.

17. Irrigation protocol EDTA for carpet strip creation NaOCl 0,5-6% after each used tool. The final irrigation Protocol: NaOCl 0,5-6% heated and activated by means of ultrasonic nozzles three times for 30 seconds with regular replacement of solution EDTA 15-20% is activated no more than 1 min by means of ultrasonic nozzles three times for 20 seconds with regular replacement of solution NaOCl 0,5-6% heated and activated by means of ultrasonic nozzles for 30 seconds. Sterile saline or distilled water should be used whenever replacement of the irrigation solution! In the treatment of acute and chronic periodontitis the 2% solution of chlorhexidine bigluconate must be entered into the protocol.

18. Clinical case No.1.

19. Clinical case No.2.

20. Clinical case No.3.

21. Clinical case No.4.

22. Clinical case No.5.

23. Clinical case No.6.

24. Clinical case No.7.

25. Clinical case No.8. Tooth 46 before treatment Tooth 36 after 8 months of treatment

26. Clinical case No. 9 Tooth 47 before treatment Tooth 47 after treatment

27. Conclusions:Conclusions: The basis of today's root canals irrigation system Protocol is a sodium hypochlorite solution with the concentration of 3.0 to 5.2% with the indispensable heating and / or mechanical activation Equally important is 15-20% solution of EDTA, which is also necessary to activate mechanically In the treatment of acute and chronic periodontitis it is necessary to enter the 2% solution of chlorhexidine bigluconate into the Protocol Antiseptic liquids produced by TehnoDent company is highly competitive with its efficiency, and in some criteria exceeds its counterparts.