1. Audit of the atrial fibrillation in the Baix Ebre. AFABE Study: estimation of unknown prevalence and no- treatment. AFABE study. Unknown atrial fibrillation. Authors & Affiliations Josep L Clua-Espuny1, Emmanuel Gim é nez-Garcia2, Ram ó n Bosch-Princep3, Carles L ó pez-Pablo3, I ñ igo Lechuga-Duran4, Anna Panisello- Tafalla1, Jorgina Lucas-Noll1, Llu ï sa Queralt-Tomas1, N ú ria Gonz á lez-Rojas5, Miquel Gallofr é L ó pez6 On Behalf of AFABE Group Investigators1. Rationale : The atrial fibrillation (AF) means a serious problem of public health. Aim was to estimate the undiagnosed (uAFp) and overall (oAFp) prevalences and associated factors with in Baix Ebre, a public health-service area in Catalonia, north-eastern Spain. Methods & Results Multicentric, cross-sectional study, with subjects randomly selected among the attended population over 60 years by primary care teams. Information was collected through ECGs, electronic medical history, reviews and medical interviews. Descriptive and logistic regression analysis was performed to know what factors could be associated to undiagnosed AF. 1043 subjects were recruited (47.1% male), mean age: 73.1 SD:7.8. oAFp was 10,9% (IC95% 9.1- 12.8%) progressively increasing with age; higher in men than in women until ≥85 where is inverted (22.5%vs26.2%). uAFp was 2.2% (IC95% 1.3-3.1%) and a higher risk of undiagnosis was found in men ≥75 year-old (OR 2.5 IC95% 1.0-6.2) with heart failure history (OR 5.2 IC95% 1.3-20.9), who live in rural areas and without ECG performed in last two years (OR 15.9 IC95% 1.5-160.1). Conclusion High oAFp with a 20.1% of unknown AF was detected in >60 year-old population and the 23.5% of all had no-treatment with oral anticoagulation. The undiagnosis was associated with male gender, age over 75, previous symptoms, heart failure, living in rural areas and not having any ECG recently performed (last 2 years). Clinical Relevance The progressive ageing is associated to an increase of the AF prevalence (24.4%) with around 1/5 undiagnosed and 43.5% (20.1% uAFp + 23.5% dAFp) untreated. Key words: Atrial fibrillation. Prevalence. Community based study. CHA2DS2-VASc. HAS-BLED. Anticoagulation for atrial fibrillation. The diagnosed percentage of patients >60 year-old with AF non-treated with OAC was 24.35% (IC95% 19.7-28.9). The non-treatment percentage when it would be indicated ( CHA2DS2VASC ≥2) 1 was 23.53 %(IC95% 18.7-29.1) (1) Primary care. Institut Català de la Salut. Terres de l’Ebre. Tortosa. España. (2) Economía de la Salut. Antares Consulting, Barcelona. (3) USR Terres de l’Ebre. IDIAP Jordi Gol-IISPV. Tortosa. (4) Cardiology. Institut Catala de la Salut. Terres de l’Ebre. Tortosa. España. (5) Economía de la Salud. Boehringer-Ingelheim. España, Sant Cugat del Vallés. (6) Pla Director de la Malaltia Vascular Cerebral de Catalunya. Dpt de Salut Cataluña, Barcelona. EAP TORTOSA 1-EST. CAP TEMPLE.

2. Audit of the atrial fibrillation in the Baix Ebre. AFABE Study: estimation of unknown prevalence and no- treatment. AFABE study. Unknown atrial fibrillation. Authors & Affiliations Josep L Clua-Espuny1, Emmanuel Gim é nez-Garcia2, Ram ó n Bosch-Princep3, Carles L ó pez-Pablo3, I ñ igo Lechuga-Duran4, Anna Panisello- Tafalla1, Jorgina Lucas-Noll1, Llu ï sa Queralt-Tomas1, N ú ria Gonz á lez-Rojas5, Miquel Gallofr é L ó pez6 On Behalf of AFABE Group Investigators1. Rationale : The atrial fibrillation (AF) means a serious problem of public health. Aim was to estimate the undiagnosed (uAFp) and overall (oAFp) prevalences and associated factors with in Baix Ebre, a public health-service area in Catalonia, north-eastern Spain. Methods & Results Multicentric, cross-sectional study, with subjects randomly selected among the attended population over 60 years by primary care teams. Information was collected through ECGs, electronic medical history, reviews and medical interviews. Descriptive and logistic regression analysis was performed to know what factors could be associated to undiagnosed AF. 1043 subjects were recruited (47.1% male), mean age: 73.1 SD:7.8. oAFp was 10,9% (IC95% 9.1- 12.8%) progressively increasing with age; higher in men than in women until ≥85 where is inverted (22.5%vs26.2%). uAFp was 2.2% (IC95% 1.3-3.1%) and a higher risk of undiagnosis was found in men ≥75 year-old (OR 2.5 IC95% 1.0-6.2) with heart failure history (OR 5.2 IC95% 1.3-20.9), who live in rural areas and without ECG performed in last two years (OR 15.9 IC95% 1.5-160.1). Conclusion High oAFp with a 20.1% of unknown AF was detected in >60 year-old population and the 23.5% of all had no-treatment with oral anticoagulation. The undiagnosis was associated with male gender, age over 75, previous symptoms, heart failure, living in rural areas and not having any ECG recently performed (last 2 years). Clinical Relevance The progressive ageing is associated to an increase of the AF prevalence (24.4%) with around 1/5 undiagnosed and 43.5% (20.1% uAFp + 23.5% dAFp) untreated. Key words: Atrial fibrillation. Prevalence. Community based study. CHA2DS2-VASc. HAS-BLED. Anticoagulation for atrial fibrillation. The diagnosed percentage of patients >60 year-old with AF non-treated with OAC was 24.35% (IC95% 19.7-28.9). The non-treatment percentage when it would be indicated ( CHA2DS2VASC ≥2) 1 was 23.53 %(IC95% 18.7-29.1) (1) Primary care. Institut Català de la Salut. Terres de l’Ebre. Tortosa. España. (2) Economía de la Salut. Antares Consulting, Barcelona. (3) USR Terres de l’Ebre. IDIAP Jordi Gol-IISPV. Tortosa. (4) Cardiology. Institut Catala de la Salut. Terres de l’Ebre. Tortosa. España. (5) Economía de la Salud. Boehringer-Ingelheim. España, Sant Cugat del Vallés. (6) Pla Director de la Malaltia Vascular Cerebral de Catalunya. Dpt de Salut Cataluña, Barcelona. EAP TORTOSA 1-EST. CAP TEMPLE.