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Function of Sertoli cell Availability of nutrients and supports

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Presentation on theme: "Function of Sertoli cell Availability of nutrients and supports"— Presentation transcript:

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2 Function of Sertoli cell Availability of nutrients and supports
phagocytosis of discarded spermids cytoplasm Regulation for the release of spermatozoa Secreteion of tubular fluid androgen-binding protein (ABP) inhibin which regulates hormone production Form a part of the blood-testis barrier Availability of nutrients and supports

3 Blood-Testis Barrier * endothelium of capillary * basement membrane
* connective tissue of spermatogenic epith * tight j. of Sertoli cell

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5 Interstitial area of Testis
* ~ 34% of total volume * L.C.T with enriched blood and lymphatic vessels * Leydig cells : - large, ovoid acidophilic - round nucleus with dispersed chromatin - apparent nucleoli - secrete androgen

6 Tubule rectus & Rete testis
* no spermatogenic cells * replacement with simple cuboidal epi.

7 Epididymis *serious tubules connecting rete testis and ductus deferen
* three parts: -head: ductuli efferentes -body -tail * functions as accumulation, storage and maturation of spermatozoa ductus epididymidis

8 Ductuli efferentes * 8-12 convoluted ducts connecting with rete testis
* a single layer of epithelial cells with two types: - tall columnar & cilliated c. - short non-ciliated c.

9 Ductus epididymidis single duct pseudostratified epith. of
uniform height sterocilia (microvilli) abundant smooth muscles function of absorption and secretion

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11 Ductus deferens Mucosa Muscularis: Adventitia:
Epith.:pseudostratified columnar epith. Mucosa Lamina propria: C.T with enriched elastic f. 3 layers of S.M., inner & outer layers: longitudinal, middle layer: circumferential . Muscularis: Adventitia: fibrosa

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13 Prostate * An aggregative of 3 group of glands Mucosal gland
Submucosal gland Main prostate gland * Epith. ranges from simple cuboidal-columnar to pseudostratified columnar * embeded within a fibromuscular stroma

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