1. Cholingeric Agonist Practice Questions

2. Pretest question The enzyme that is inhibited by echothiophate iodide isThe enzyme that is inhibited by echothiophate iodide is a. Tyrosine hydroxylasea. Tyrosine hydroxylase b. Acetylcholinesterase (AChE)b. Acetylcholinesterase (AChE) c. Catechol -O-methyltransferase (COMT)c. Catechol -O-methyltransferase (COMT) d. Monoamine oxidase (MAO)d. Monoamine oxidase (MAO) e. Carbonic anhydrasee. Carbonic anhydrase

3. Pretest question The reversible cholinesterase inhibitor indicated in the treatment of Alzheimer’s disease is The reversible cholinesterase inhibitor indicated in the treatment of Alzheimer’s disease is a. Tacrine a. Tacrine b. Edrophonium b. Edrophonium c. Neostigmine c. Neostigmine d. Pyridostigmine d. Pyridostigmine e. Ambenonium e. Ambenonium

4. Pretest question All of the following drugs are used topically in the treatment of chronic wide-angle glaucoma. Which of these agents reduces intraocular pressure by decreasing the formation of the aqueous humor? All of the following drugs are used topically in the treatment of chronic wide-angle glaucoma. Which of these agents reduces intraocular pressure by decreasing the formation of the aqueous humor? a. Timolol a. Timolol b. Echothiophate b. Echothiophate c. Pilocarpine c. Pilocarpine d. Isofluorphate d. Isofluorphate e. Physostigmine e. Physostigmine

5. Pretest Question The cholinomimetic drug that is useful for treating postoperative abdominal distention and gastric atony is The cholinomimetic drug that is useful for treating postoperative abdominal distention and gastric atony is a. Acetylcholine (ACh)a. Acetylcholine (ACh) b. Methacholineb. Methacholine c. Carbacholc. Carbachol d. Bethanechold. Bethanechol e. Pilocarpinee. Pilocarpine

6. Pretest question Pralidoxime chloride is a drug that a. Reduces the vesicular stores of catecholamines in adrenergic and dopaminergic neurons a. Reduces the vesicular stores of catecholamines in adrenergic and dopaminergic neurons b. Blocks the active transport of choline into cholinergic neurons b. Blocks the active transport of choline into cholinergic neurons c. Reactivates cholinesterases that have been inhibited by organophosphate cholinesterase inhibitors c. Reactivates cholinesterases that have been inhibited by organophosphate cholinesterase inhibitors d. Stimulates the activity of phospholipase C with increased formation of inositol d. Stimulates the activity of phospholipase C with increased formation of inositol triphosphate triphosphate e. Inhibits the reuptake of biogenic amines into nerve terminals e. Inhibits the reuptake of biogenic amines into nerve terminals

7. Pretest Question The cholinesterase inhibitor that is used in the diagnosis of myasthenia gravis isThe cholinesterase inhibitor that is used in the diagnosis of myasthenia gravis is a. Edrophonium chloridea. Edrophonium chloride b. Ambenonium chlorideb. Ambenonium chloride c. Malathionc. Malathion d. Physostigmine salicylated. Physostigmine salicylate e. Pyridostigmine bromidee. Pyridostigmine bromide

8. Pretest Question Of the following effects, which is not elicited by activation of the parasympathetic nervous system? Of the following effects, which is not elicited by activation of the parasympathetic nervous system? a. Decreased heart rate a. Decreased heart rate b. Increased tone of longitudinal smooth muscles of the intestine b. Increased tone of longitudinal smooth muscles of the intestine c. Contraction of skeletal muscles c. Contraction of skeletal muscles d. Contraction of the detrusor of the urinary bladder d. Contraction of the detrusor of the urinary bladder e. Secretion of fluid from the lacrimal glands e. Secretion of fluid from the lacrimal glands

9. Pretest Question Which one of these drugs are used in Glaucoma?Which one of these drugs are used in Glaucoma? a. Pilocarpinea. Pilocarpine b. Methylphenidateb. Methylphenidate c. Propranololc. Propranolol d. Ritodrined. Ritodrine e. Phenoxybenzaminee. Phenoxybenzamine

10. Pretest Question

11. Practice Question Which of the following would not be expected as a sign of cholinesterase inhibitor-insecticide poisoning. A. A.Mydriasis B. B.Increased Salivation C. C.Increased bowel sounds D. D.Urinary urgency E. E.Skeletal muscle spasms  Paralysis

12. Practice Question In the previous question, what would be the treatment for this patient? A. A.Atropine and epinephrine B. B.Epinephrine and Isoproterenol C. C.Norepinephrine and Propranolol D. D.Atropine and Praxilodime E. E.Prolidoxine and Propanolol

13. Practice Question Which of the following drugs can be used to reduce IOP in treatment of Glaucoma? A. A.Pilocarpine B. B.Azetozelomide C. C.Neostigmine D. D.Timolol E. E.All of the above

14. Practice Question Which of the following cholinesterase inhibitors has the shortest duration of action? A. A.Neostigmine B. B.Phyostigmine C. C.Edrophonium D. D.Echothiophate E. E.Trimethaphan