1. Design and Implementation of a Smartphone-Based portable Ultrasound Pulsed-Wave Doppler device for blood flow measurement Huang, C. C., Lee, P. Y., Chen, P. Y., & Liu, T. Y. (2012). Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on, 59(1), 182-188. Presenter ： Li-Chen Yaung Adviser ： Dr. Yi-Chun Du Date : 2015/12/23 1

2. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 2 Outline  Introduction  Materials and methods  Result  Discussion  Conclusion

3. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 3 Introduction

4. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 4 Introduction(1/4) Doppler ultrasound is widely used in medicine  Assessing blood flow.  Diagnosing various cardiac.  Blood vessel diseases in the central and peripheral circulation.

5. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 5 Introduction(2/4) Doppler ultrasound is widely used in medicine. it is capable of real time measurement. it is noninvasive.

6. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 6 Introduction(3/4)  Blood flow information can be regarded as an index for monitoring physiological functions as well as blood pressure and blood oxygenation.

7. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 7 Introduction(4/4)  The arterial flow velocity was different after exercise or during sleep apnea.  It is not convenient to use a commercial ultrasound duplex scanner for Doppler measurements during exercise or sleep.  We need a portable Doppler ultrasound device with a surface probe.

8. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 8 Materials and methods

9. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 9 Doppler ultrasound : principles sonoworld.com

10. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 10 Blood flow

11. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 11 Incident angle

12. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 12 System architectures

13. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 13 The specifications of analog pulsed-wave Doppler Center operation frequency10MHz Pulse repetition frequency (PRF) 9.25, 18.5, 39 and 78 kHz Transmitted pulse duration0.5μ Output voltage±50 V Range gate (adjustable)0.4 to 19 mm Wall filter250 Hz

14. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 14 Sampling method of ultrasound blood flow

15. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 15 Flowchart of Doppler spectrogram analysis on smartphone

16. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 16 System verification The stroke rate was set to 15 beats/min at a peak flow velocity of 120 cm/s

17. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 17 Measurement setup

18. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 18 Doppler spectrogram of flowing blood from Couette flow phantom

19. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 19 Result

20. 生醫系統整合實驗室 Integrated Biomedical System Laboratory Animal experiments

21. 生醫系統整合實驗室 Integrated Biomedical System Laboratory Animal experiments

22. 生醫系統整合實驗室 Integrated Biomedical System Laboratory Application of the portable Doppler device for human blood flow monitor

23. 生醫系統整合實驗室 Integrated Biomedical System Laboratory 23 Conclusion

24. 生醫系統整合實驗室 Integrated Biomedical System Laboratory Conclusion  A 10-MHz surface transducer was designed for measuring the blood flow velocity without the need for an operator-held probe.  In this system, both the signal and spectrogram can be stored and displayed in real time.  A maximum flow velocity of 120 cm/s could be measured by this device.  Although the Doppler spectrogram was influenced slightly by noise, the result was in a good agreement with the measurement from a commercial scanner