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Coordinators Dr. Anjum Afshan Dr. Tarig Gally

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1 Coordinators Dr. Anjum Afshan Dr. Tarig Gally
Introduction Rep Coordinators Dr. Anjum Afshan Dr. Tarig Gally

2 THE REPRODUCTIVE SYSTEM MODULE REP 321 Phase II (2016)

3 THE REPRODUCTIVE SYSTEM MODULE REP 321 Phase II (2016)

4 THE REPRODUCTIVE SYSTEM MODULE REP 321 Phase II (2016)
Knowledge Graduate should have sufficient knowledge and understanding of: The normal structure, function and development of the human body & interaction between body & mind. The normal pregnancy and child birth, the principles of antenatal & postnatal care. The etiology, pathogenesis, clinical presentation, natural history & prognosis of common physical and mental disease, particular those which pose acute danger to function, life of the community. Common diagnostic tests and procedures, their uses, limitations and costs The principles of health education, disease prevention, rehabilitation and the care of the suffering and dying. The principles and ethics related to health care and the Islamic and legal responsibilities of the medical profession.

5 THE REPRODUCTIVE SYSTEM MODULE REP 321 Phase II (2016)
Skills Graduate should acquire the skills of: Take a tactful, accurate and organized medical history. Perform a gentle & accurate physical and mental examination. Integrate history & physical examination to reach a provisional diagnosis of differential diagnosis. Select the most appropriate & cost effective diagnostic procedures. Formulate a management plan. Counsel patients & families clearly regarding diagnostic and therapeutic procedures before eliciting consent. Perform common life-saving procedures. Use information resources to obtain further knowledge and interpret medical evidence critically and scientifically. Communicate clearly & considerately with other health professionals.

6 THE REPRODUCTIVE SYSTEM MODULE REP 321 Phase II (2016)
Attitude Graduate should have the attitude of: Respect for every human being & abide by relevant Islamic ethics. A desire to ease pain and suffering. Willingness to work in a team with other health professionals. Responsibility to remain a life-long learner & maintain the highest ethical & professional standards. Referring patients to other health professional when needed. A realization that it is not always in the interest of patients to pursue every diagnostic or therapeutic possibility.

7 THE REPRODUCTIVE SYSTEM MODULE REP 321 Phase II (2016)
Curriculum Map YOU Are Here… Year 1 Year 2 Year 3 Year 4 Year 5 Year 6 Internship Phase I Phase II Phase III

8 THE REPRODUCTIVE SYSTEM MODULE REP 321 Phase II (2016)
Structure of the Module Module is composed of: Course No. Course Title Contact Hours Credit Hours Rep 321 Reproductive System L T/S P CL/ P PBL SDL 46 5 9 4 1 6

9 THE REPRODUCTIVE SYSTEM MODULE REP 321 Phase II (2016)
Aims: Understand the processes of human reproduction from the production of gametes, establishment of the embryo through to independent life by the newborn infant. Understand common problems & disorders of the male& female reproductive tract, the mechanisms of contraception and the sexual transmission of diseases. Acquire skills & working knowledge & understanding of the principles and concepts applicable to the Reproductive System, in general.

10 THE REPRODUCTIVE SYSTEM MODULE REP 321 Phase II (2016)
Objectives: By the end of this module, the student should be able to: 1.Describe the development of the reproductive tract in the male & the female during fetal life, its genetic and hormonal control and abnormalities. 2.Describe the mechanisms underlying puberty in the male and the female and the sequence of associated changes. 3.Describe the anatomy of the male reproductive system, the histology of testis and accessory sexual organs and the formation of male gamete. 4.Describe the role of gonadotropins in the control of male gamete production and steroid genesis, and the effects of androgens upon the body. 5.Describe common pathological changes of the male reproductive system, including prostatic and testicular cancer.

11 THE REPRODUCTIVE SYSTEM MODULE REP 321 Phase II (2016)
6.Describe the anatomy of the female reproductive tract, and the histology of the ovaries, uterus, cervix and vagina, including the ovarian cycle (the formation of the female gamete), the uterine cycles. 7.Describe and explain the endocrine control of the production of the female gamete and the effects of ovarian steroid hormones upon the reproductive tract which underlie the normal menstrual cycle. Describe some common menstrual abnormalities. 8.Describe the pathophysiology of the menopause. 9.Describe the common pathological changes of the female reproductive system, including cancers of the reproductive tract and the basic cellular changes and the precancerous lesions. 10.Describe the Breast, anatomy, histology, common pathology, and lactation. 11.Describe reasons for infertility in the male and female and methods for assisted reproduction. 12.Describe the process of fertilization and implantation, the structure of the placenta, and the role of the endocrine activity of the placenta in the maintenance of pregnancy.

12 THE REPRODUCTIVE SYSTEM MODULE REP 321 Phase II (2016)
13.Describe the maternal adaptations to pregnancy, the underlying mechanisms involved and pregnancy-induced maternal disorders. 14.Describe the normal pattern of embryonic and fetal development, the ways in which it may be assessed, and the principles of detection of fetal abnormalities. 15.Describe the physiological adaptation of the fetus to intrauterine, the ways in which the neonate adapts to an extra uterine existence, and some common problems of neonates. 16.Describe the processes involved in a normal labor and delivery and some common problems of labor. 17.Understand the biochemistry of semen and physiology of ejaculation.

13 THE REPRODUCTIVE SYSTEM MODULE REP 321 Phase II (2016)
Transferable Skills: By the end of this module, students will demonstrate the ability to: 1. Assimilate and integrate information from lectures, practical sessions, tutorials, clinical presentation sessions and independent learning activities. 2. Gain practical skills associated with the dissection of the cadaver and the examination of the living. 3. Interpret two-dimensional images of the Reproductive System from radiographic techniques. 4. Explain the pathology of Reproductive System and drug action in relation to the underlying processes.

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Module details: DEPARTMENT LECT. TUTOR. Clinical Presentation PRACT. STUDENT DIR. L. PBL Anatomy 6 1 ---- 3 2 - Pathology 9 Physiology Pharmacology 5 Biochemistry Obstetrics & Gynecology Pediatrics Histology 4 Radiology ----- ------ Microbiology --- Parasitological Total 46

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Department of Pathology Lecture : Pathology of Vulva, Vagina Lecture : Pathology of Cervix Lecture: Benign Uterine Pathology. Lecture: Malignant neoplasms of the uterine corpus. Lecture: Tumors of the ovary. Lecture: Trophoblastic pathology. Lecture: Diseases of Prostate. Lecture: Pathology of the testis & Testicular Adnexa. Lecture Pathology of the breast Practical: Diagnosis of pathological specimens of male genital system. Practical: Diagnosis of pathological specimens of female genital system I. Practical: Diagnosis of pathological specimens of female genital system II. PBL Female genital tract pathology.

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Department of Physiology Lecture: The reproductive system: An overview. Lecture: The puberty Onset of The major physiological changes. Lecture: The menstrual cycle. Lecture: Physiology of pregnancy. Lecture: Maternal response to pregnancy. Lecture : The physiology of Parturition Lecture The physiology of lactation Lecture: Fetal physiology. Lecture: The menopause changes underlying the climacteric symptoms. Tutorials Male & female sexual behavior SDL Review Hypothalamus- anterior pituitary –gonadal axis in male and female. Hormonal disorders of menstrual cycle Hormonal disorders of menstrual cycle.

17 THE REPRODUCTIVE SYSTEM MODULE REP 321 Phase II (2016)
Department of Pharmacology Lecture: Drugs during pregnancy. Reproductive Pharmacology: Oxolytics & Tocolytics drugs. infertility Pharmacology Erectile dysfunction Pharmacology Oral contraception Pharmacology

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Department of Clinical Biochemistry  Lecture: Testicular steroid genesis and its endocrine Control: part I. Lecture: Testicular steroid genesis and its endocrine control: part II. Lecture: Female sex hormones: part I. Lecture: Female sex hormones: part II. Lecture : Prenatal Diagnosis Lecture : Biochemical investigations of infertility Tutorials Tutorial: Disorders of gonadal function in male. Tutorial: Disorders of gonadal function in female.

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Department of Obstetrics and Gynecology Lecture: Antenatal Care SDL: Normal Labor (video show). Ectopic pregnancy Clinical Presentation Pre Malignant And Malignant Condition of The Cervix Heavy Menstrual Period Miscarriages

20 THE REPRODUCTIVE SYSTEM MODULE REP 321 Phase II (2016)
Department of Pediatrics Lecture: Ambiguous genitalia. Clinical Presentation: Normal & abnormal Puberty. Department of Radiology Practical: Radiology of Reproductive System.

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  Department of Anatomy Lecture: Gross anatomy of the female reproductive tract. Lecture: Gross anatomy of the male reproductive tract. Lecture: Normal & abnormal embryology of the male reproductive tract. Lecture: Normal and Abnormal Embryology of the female reproductive tract. Lecture: Embryonic and fetal period. Lecture placenta and fetal membranes Tutorial: Perineum Practical: Dissection of male reproductive tract. Practical: Dissection of female reproductive tract. Practical bony pelvis SDL Directed Learning Pelvic Wall Directed Learning: In vitro and in vivo Fertilization & Implantation

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Department of Histology Lecture: Histology of normal male reproductive tract. Lecture: Histology of normal female reproductive tract. Lecture: Spermatogenesis and Oogenesis Lecture: Histology of the mammary gland.  Practical: Histology of the normal male reproductive tract. Practical: Histology of the normal female reproductive tract.

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Department of Parasitology Lecture: Trichomoniasis & Candidiasis. Lecture: Acquired and Congenital Toxoplasmosis.  Tutorial: Sexually Transmitted Disease. (STD)

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Department of Microbiology Lecture: Pelvic inflammatory diseases Lecture: Viral diseases in pregnancy

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List of Suggested Reading References Name of Books and Authors 1) Clinical anatomy for medical students (8th Ed) Richard Snell 2) Lang man’s Medical Embryology T.W.Sadler 3) Color text book of Histology 2nd Ed Gartner L.P. & Hiatt J.L. 4) Grant Atlas of Anatomy 12th edition Grant J.C.B. 5) Di Fiore’s Atlas of Histology with Functional Correlation 9th Ed. Eroschenko V.P. 6) Review of Medical Physiology22th edition Ganong W.F. 7) Text book of medical Physiology11th edition Guyton A.C. & Hall J.E. 8) MCQs in Human Physiology Roddie I.C. & Wallace W.F.M. 9) Basic Pathology Robbing and Cot ran: Pathological basis of disease 8th edition 10) Lippincott's Pocket Pathology, 2nd Edition, • Kumar, Cot ran, Robbins 11) Wills’ Biochemical Basis of Medicine Gillham, B. J.H.Thomas 12) Clinical Biochemistry Marshall 13) Nelson Textbook of pediatrics Nelson 14) Basic & clinical pharmacology. Katzung 15) Lippincott's illustrated review pharmacology3rd edition 2006 Lippincott's 16) Radiology & imaging for medical students David Sutton 17) Current: Surgical diagnosis& Treatment Way, L.W., Doherty, GM 18) Obstetrics by ten teacher Ten Teacher 19) Gynecology by Ten Teacher Ten Teacher

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Assessment Formative: This form of assessment is designed to give feedback to help student, to identify areas for improvement. It includes a mixture of MCQs, short answer-questions (SAQs), extended matching questions (EMQs), problems-solving exercises and independent learning activities in all subjects. Summative This type of assessment is used for judgment or decisions to be made about students’ performance. It serves as: Verification of achievement for the student satisfying requirement. Motivation of the student to maintain or improve performance. Certification of performance. Grades. In this Course students’ performance will be assessed according to the following: Quizzes Marks SDL assessment Marks Final End of module Exam (Two Hours) Marks Final OSCE (Practical) Marks Viva Voce Exam Marks Total = 100 Marks 

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NOTE: Class attendance and participation are extremely important to STUDENTS’ learning and also considered in the evaluation of course grade. This course is recommended for students who will spend some time and put an effort to win all the benefits of this interesting module. Students are encouraged to achieve this goal. Teaching faculty and coordinators are always available for guidance in offices during office hours and through s.

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MODULE MEMBERS CONTACTS NAME DEPARTMENT Dr. Aymen Warille Anatomy Dr. Abu Baker Dr. Abdallah Dr. Hamza Dr. Nermeen Dr. Mawahib Dr. Serega Dr. Fatima Dr. Samah Physiology Dr. Abdalhafez Dr. Sahar Galal Histology Dr. Hosam Ghobashi Dr. Amira Biochemistry Dr. Mohammad Quddus

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Dr. Somia Bashir Pediatrics Dr. Mona Madbouly Dr. Gamal Dr. Rashid Awad Dr. Rania Abdeen Obs. & Gyn. Dr. Anjum Afshan Dr. Abdul Rahim Dr. Tarig Gally Dr. Halima Mustafa Pharmacology Dr. Abuzer Dr. Amany Khalifa Parasitology Dr. Omar Dr. Nuha Pathology Dr. Hussain Gad Dr. Naheed Microbiology Dr. Abdulkhaleg

30 THE REPRODUCTIVE SYSTEM MODULE REP 321 Phase II (2016)
Icons (standards) The following icons have been used to help identify the various experiences students will be exposed to. Learning objectives  Content of the lecture Independent learning from textbooks Independent learning from the CD-ROM. The computer cluster is in the 2nd floor of the medical library, building G . Independent learning from the Internet. Problem-Based Learning Self- Assessment (The answer to self-assessment exercises will be discussed in tutorial sessions) The main concepts

31 THE REPRODUCTIVE SYSTEM MODULE REP 321 Phase II (2016)
Lectures Department 1 The Reproductive Module Introduction Coordinator 2 The Reproductive System: An Overview. Physiology 3 Gross Anatomy Of The Male Reproductive Tract. Anatomy 4 The Puberty Onset & The Major Physiological Changes 5 Histology Of Normal Male Reproductive Tract. Histology 6 Pathology Of The Testis & Testicular Adnexa Pathology 7 Gross Anatomy Of The Female Reproductive Tract 8 Diseases Of Prostate 9 Normal & Abnormal Embryology Of The Male Reproductive Tract 10 Histology Of Normal Female Reproductive Tract 11 Normal & Abnormal Embryology Of The Female Reproductive Tract 12 The Menstrual Cycle 13 Testicular Steroid genesis & Its Endocrine Control1 Clinical Biochemistry 14 Testicular Steroid genesis & Its Endocrine Control11 15 Spermatogenesis Oogenesis

32 THE REPRODUCTIVE SYSTEM MODULE REP 321 Phase II (2016)
Histology Of The Mammary Gland Histology 17 Placenta And Fetal Membrane Anatomy 18 Breast Pathology Pathology 19 Embryonic And Fetal Period 20 Physiology Of Pregnancy Physiology 21 Maternal Response To Pregnancy 22 Trophoblastic Pathology 23 Female Sex Hormones :Part I Clinical Biochemistry 24 Female Sex Hormones :Part II 25 Fetal Physiology 26 Viral Diseases In Pregnancy Microbiology 27 . Drugs During Pregnancy Pharmacology 28 Tumors Of The Ovary 29 Pathology Of Vulva, Vagina 30 Antenatal Care Obs. & Gyn. 31 Prenatal Diagnosis

33 THE REPRODUCTIVE SYSTEM MODULE REP 321 Phase II (2016)
The Physiology Of Parturition Physiology 33 Pathology Of Cervix Pathology 34 Reproductive Pharmacology : Oxolytics & Tocolytics Drugs Pharmacology 35 The Physiology Of Lactation 36 The Menopause Changes Underlying The Climacteric Symptoms 37 Erectile Dysfunction 38 Benign Uterine Pathology 39 Ambiguous Genitalia Pediatric 40 Biochemical Investigations Of Infertility Clinical Biochemistry 41 Infertility Drugs 42 Malignant Neoplasm’s Of The Uterine Corpus 43 Pelvic Inflammatory Disease Microbiology 44 Trichomoniasis And Candidacies 45 Acquired And Congenital Toxoplasmosis Parasitology 46 Oral Contraception

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Tutorials 1 Perineum Anatomy 2 Disorders Of Gonadal Function In Male Clinical Biochemistry 3 Disorders Of Gonadal Function In Female 4 Male & Female Sexual Behavior Physiology 5 Sexual Transmitted Disease. (Parasites) Parasitology

35 THE REPRODUCTIVE SYSTEM MODULE REP 321 Phase II (2016)
Practical 1 Dissection Of Male Reproductive Tract Anatomy 2 Histology Of The Normal Male Reproductive Tract Histology 3 Dissection Of Female Reproductive Tract 4 Practical Bony Pelvis 5 Histology Of The Normal Female Reproductive Tract 6 Diagnosis Of Pathological Specimens Of Male Genital System Pathology 7 Diagnosis Of Pathological Specimens Of Female Genital System I 8 Diagnosis Of Pathological Specimens Of Female Genital System II 9 Radiology Of Reproductive System Radiology

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1 PBL Female Genital Tract Pathology Pathology

37 THE REPRODUCTIVE SYSTEM MODULE REP 321 Phase II (2016)
CLINICAL PRESENTATION 1 Puberty :Normal & Abnormal Pediatrics 2 Pre Malignant And Malignant Condition Of The Cervix Obs. & Gyn. 3 Heavy Menstrual Period 4 Miscarriages SDL Review Of Hypothalamus- Anterior Pituitary- Gonadal Axes In Male & Female Physiology Hormonal Disorders Of Menstrual Cycle Pelvic Floor Anatomy In vitro and In vivo Fertilization & Implantation 5 Normal Labor ( Video Show ) 6 Ectopic Pregnancy


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