1. Medication Compliance Alarm (MCA) Senior Design I Final Presentation

2. Team Members Team Leader Electrical Engineer Website Image Processing System Integration Electrical Engineer Hardware Design Pic Programming Jarvis Kenerson Team AdvisorElectrical Engineer Calendar/ Alarm System System Integration Eric Myers Augustine Tran Dr. Randy Follett

3. Outline Problem Solution Constraints o Technical o Practical Testing Prototype Future Goals Questions

4. Problem 50% to 70% of Americans do not take their medicine as prescribed [1] Current medication reminder devices do not have a clear way to monitor that medication is being removed from the storage containers. [2]

5. Solution The MCA is a user-friendly device that monitors noncompliance more accurately than other existing products. The MCA: - Stores daily medication - Alerts patients during dosage times - Verifies if medication has left the device - Caregivers can visually observe medication compliance

6. Technical Constraints NameDescription Power SupplyThe device must use 120V AC. USB The device must use USB interface with computer. Quantity of Pill Containers The device must have 28 containers. Empty Container Detection The device has to detect when a pill container is empty. Remote Container Visibility The device must be able to visually see the pill container.

7. System Overview Webcam Power Supply Patient NotificationMicrocontroller Computer Software Remote Caregiver Access

8. Practical Constraints Ethical The device must not be used to spy on the patient.

9. Practical Constraints Sustainability  Device must be able to handle moderate use  To prevent complaints, the device must be easy to use and not cause stress to patients.

10. Prototype Breadboard Buzzer LEDs PIC24 ON/OFF USB TTL Serial Cable

11. Testing USB Interface  Logic Port Analyzer Waveform Receiving Corresponding LED Char Value

12. Testing Patient Notification  Decibel meter used to measure intensity of Buzzer for patient notification.

13. Testing Patient Notification  Voltage and Current characteristics of patient notification LEDs. Voltage (V)Current (mA) LEDs1.969.08

14. Prototype Software

16. Progress Software

17. Prototype Software

19. Remote Access

20. Prototype Software

21. Testing Text-subsystem Software can send an email that will be received as an SMS text at caregiver’s cell phone

22. Quantity of Pills Can hold up to 20 jelly beans (75% the size of a size 0 capsule). Approximately 15 size 0 capsules will fit into cup. [3]

23. Device Pill Container

24. Empty Pill Detection

25. Detects the empty symbol in various locations Detection time varies with distance where camera is centered

26. Empty Pill Detection

30. 10% error with single tic-tac Limitations of prototype camera are the root cause of this error.

31. Sunny Day Case The alarm triggers and turns on webcam Webcam determines that pill container is full Appropriate character is sent through USB/Serial connection to microcontroller Microcontroller blinks corresponding LED and sounds buzzer Webcam continues to check pill container until empty cup is visible After webcam sees empty cup, the compliance report is updated as taken

32. Rainy Day Case 1 The alarm triggers and turns on webcam Webcam determines that pill container is empty at time of medication reminder Webcam sends text message to caregiver Compliance report updated as refill error

33. Rainy Day Case 2 The alarm triggers and turns on webcam Webcam determines that pill container is full Appropriate character is sent through USB/Serial connection to microcontroller Microcontroller blinks corresponding LED to compartment and sounds buzzer Webcam continues to check pill container until empty cup is visible Patient does not take medicine in given time limit Alarm turns off, updates compliance report as missed dosage Text message is sent to caregiver

34. Working Prototype

36. Future Goals Jan.Feb.MarchAprilMay PCB Design Software Refinement PCP Population/ Packaging Testing & Debugging

37. Final Product Design

38. References [1] A.I. Wertheimer and T.M. Santella. (2003) Medication Compliance Research: Still so Far to Go. The Journal of Applied Research. [Online] 3, 254-261. Available: http://www.jarcet.com/articles/Vol3Iss3/wertheimer.htm http://www.jarcet.com/articles/Vol3Iss3/wertheimer.htm [2]http://www.xconomy.com/boston/2011/02/02/vit ality-acquired-by-healthcare-investor-soon-shiong- looks-to-expand-wireless-products-for-improving- healthy-behaviors/http://www.xconomy.com/boston/2011/02/02/vit ality-acquired-by-healthcare-investor-soon-shiong- looks-to-expand-wireless-products-for-improving- healthy-behaviors/ [3] http://www.capsuleconnection.com/capsules

39. Questions?