1. Mechanism of Action of Aspirin Carlo Patrono, et al, N Engl J Med 2005;353:2373-83

2. Maximal Capacity of Human Platelets to Synthesize Thromboxane B 2 (Panel A), Rate of TXB 2 Production in Healthy Subjects (Panel B), and Nonlinear Relationship between the Inhibition of Platelet Cyclooxygenase Activity and TXB 2 Biosynthesis in Vivo (Panel C) Carlo Patrono, et al, N Engl J Med 2005;353:2373-83

3. Absolute Effects of Antiplatelet Therapy with Aspirin on the Risk of Vascular Events (Nonfatal Myocardial Infarction, Nonfatal Stroke, or Death from Vascular Causes) in Five Groups of High-Risk Patients Carlo Patrono, et al, N Engl J Med 2005;353:2373-83

4. High-Risk Disorders for Which Aspirin Has Been Shown to Be Effective and Lowest Effective Daily Dose Carlo Patrono, et al, N Engl J Med 2005;353:2373-83

5. Benefits and Risks of Low-Dose Aspirin in Primary-Prevention Trials Carlo Patrono, et al, N Engl J Med 2005;353:2373-83

6. Estimated Rates of Upper Gastrointestinal Complications in Men, According to Age and the Presence or Absence of a History of Such Complications and Regular Treatment with Low-Dose Aspirin Carlo Patrono, et al, N Engl J Med 2005;353:2373-83