1. Enzymes Textbook Pages 69-74

2. Enzymes are important Digestion, Immune function, cell division, etc. Basically everything produced or changed in our bodies When enzymes go wrong – Lactose intolerance – Diabetes – *thyroidism – Death

3. What is an enzyme? Catalyst – Substance that speeds up a specific chemical reaction without being consumed in it – In other words, reduces the activation energy of a specific reaction

5. Ok, but how do they work? Work on a particular substrate Bind to the substrate to form the enzyme- substrate complex Then breaks apart into: 1) Products of the reaction 2) Unchanged enzyme

6. http://highered.mcgraw- hill.com/sites/0072495855/student_view0/chapter2/animation__how_enzymes_work.html http://highered.mcgraw- hill.com/sites/0072495855/student_view0/chapter2/animation__how_enzymes_work.html

7. Models of enzyme function Lock and key model

8. Models of enzyme function Induced fit model http://www.sumanasinc.com/webcontent/animations/content/enzymes/enzymes.html

9. Factors that influence enzyme activity Temperature – 37 °C for humans mostly – Denaturation Concentration of enzyme Concentration of substrate pH – Stomach vs. Intestines

10. Enzyme Cofactors of Coenzymes Molecules or elements that bind to enzymes to allow them to function – Ex: Zinc, B vitamins

11. Enzyme inhibition Competitive inhibitors

12. Enzyme inhibition Noncompetitive inhibition

13. Allosteric regulation

14. Negative feedback inhibition