Download presentation
Presentation is loading. Please wait.
Published byStephany Preston Modified over 9 years ago
1
Modelling from Sequence to Gene Regulatory Network to Phenotype
2
Network Expression The gene regulation network expresses as gene activation over time 1 5 3 4 2 Time 1 2 3 4 5 Gene activation
3
State Spaces If the system state at a given time step is determined by the previous system state, the dynamics can settle into ‘basins of attraction’, in which the system is robust to perturbation. But some changes can push the system to different behaviour. 1 5 3 4 2
4
System State After Single Perturbations
5
Perturbation
6
System State After Single Perturbations
7
Perturbation
8
System State After Single Perturbations
9
Perturbation
10
System State After Single Perturbations
11
Perturbation
12
System State After Single Perturbations The dynamics of the system have changed
13
System State After Single Perturbations Perturbation
14
System State After Single Perturbations The system has changed again
15
Such complex systems dynamics are being studied in models of gene regulation
16
System State After Single Perturbations
Similar presentations
© 2025 SlidePlayer.com Inc.
All rights reserved.