1. States of consciousness Prof. dr. Anton M.L. Coenen NICI – Department of Biological Psychology Radboud University Nijmegen The Netherlands a.coenen@nici.ru.nl

2. States of consciousness Lecture 5. Altered states of consciousness

4. (After A. Bricolo, 1975)

7. Cortical involvement in tonic-clonic seizures. Red represents increases in ictal compared to interictal cerebral blood flow. (Blumenfeld et al, 2003)

16. Korsakoff

18. Delirium

27. Normal ageing Damage Parkinson Age (years) Dopamine (%)

28. NARCOLEPSY

29. Narcolepsy: symptoms (Overeem et al., Journal of Clinical Neurophysiology, 2001)

33. LUCID DREAMING

34. DAY-DREAM

35. CONCENTRATION

36. MEDITATION

41. Dopamine release during attention and meditation (Kjaer et al, 2002)

44. HYPNOSIS

48. During hypnosis an increase in activity in parts of the cingulate cortex (part of the ‘pain matrix’) is observed. (Faymonville et al, 2003)

53. Coma is a low vigilant state caused by damage or affections of the midbrain reticular formation or by large parts of the cortex. In dementia (Alzheimer, multi-infarct dementia, Korsakoff syndrome) and delirium, disorientation in space and time can occur, together with hallucinations, confusions and a lowered state of consciousness. In narcolepsy and lucid dreaming, dream hallucinations occur. In lucid dreaming, the dreamer is ‘aware’ of his dream. In narcolepsy (REM sleep during waking), a frightening mixed perception of internal and external stimuli occur. Meditation is a technique to calm down the brain (relaxation) and to bring it in a trance-like state in which insight arises in mind, self and world. Hypnosis is a trance-like state with focused attention, in which people are sensitive for suggestions. Even feelings of pain can be reduced in the hypnotic state.