1. 1 Chapter 6 Integumentary System

2. 2 Integumentary System Functions Composed of several tissues Maintains homeostasis Protective covering Retards water loss Regulates body temperature Houses sensory receptors Contains immune system cells Synthesizes chemicals Excretes small amounts of waste

3. 3 Skin Cells Special things they do! help produce Vitamin D needed for normal bone and tooth development some cells (keratinocytes) produce substances that simulate development of some WBCs

4. 4 Layers of Skin/Tissues of Skin Epidermis Dermis Subcutaneous layer beneath dermis not part of skin

5. 5 Epidermis lacks blood vessels keratinized thickest on palms and soles (0.8-1.4mm), thinner than dermis melanocytes provide melanin rests on basement membrane stratified squamous

6. 6 Epidermis Layers of Epidermis stratum corneum stratum lucidum stratum granulosum stratum spinosum stratum basale

7. 7 Dermis contains dermal papillae binds epidermis to underlying tissues irregular dense connective tissue on average 1.0-2.0mm thick, thicker than epidermis muscle cells nerve cell processes specialized sensory receptors blood vessels hair follicles glands

8. 8 Subcutaneous Layer hypodermis loose connective tissue adipose tissue insulates major blood vessels

9. 9 Hair Follicles epidermal cells tube-like depression extends into dermis hair root hair shaft hair papilla dead epidermal cells melanin arrector pili muscle

10. 10 Nails protective coverings nail plate nail bed lunula

11. 11 Sebaceous Glands usually associated with hair follicles holocrine glands secrete sebum absent on palms and soles

12. 12 Sweat Glands sudoriferous glands widespread in skin originates in deeper dermis or hypodermis eccrine glands apocrine glands ceruminous glands mammary glands

13. 13 Regulation of Body Temperature Heat Production and Loss Radiation – primary means of heat loss. Conduction – heat from the body is directly transferred to cooler objects through contact Convection – circulation of air, warm away replaced by cooler. Evaporation – occurs when the body temp rises above normal, eccrine glands release sweat which carries heat away when evaporating.

14. 14 Regulation of Body Temperature

15. 15 Problems in Temperature Regulation Hyperthermia – abnormally high body temperature Hypothermia – abnormally low body temperature

16. 16 Skin Color Genetic Factors varying amounts of melanin varying size of melanin granules albinos lack melanin Environmental Factors sunlight UV light from sunlamps X rays darkens melanin Physiological Factors dilation of dermal blood vessels constriction of dermal blood vessels accumulation of carotene jaundice cyanosis

17. 17 Healing of Cuts A – normal skin B – deep injury, into dermis C – blood from dermal blood vessels fills the wound. D – blood clot forms E – scab, dried tissue fluid and blood clot F – blood vessels send out branches and fibroblast migrate to the area G – fibroblasts produce new connective tissue fibers, scab comes off when mostly healed

18. 18 Healing of Cuts

19. 19 Healing of Burns First degree burn – superficial partial-thickness Second degree burn – deep partial-thickness Third degree burn – full-thickness autograft homograft various skin substitutes

20. 20 Rule of Nines -Each region equals 9% -Helps in planning replacement of body fluids, electrolytes and skin

21. 21 Life Span Changes Skin becomes scaly Age spots appear Epidermis thins Dermis becomes reduced Loss of fat Wrinkling Sagging Sebaceous glands secrete less oil Melanin production slows Hair thins Number of hair follicles decrease Nail growth becomes impaired Sensory receptors decline Body temperature unable to be controlled Diminished ability to activate Vitamin D

22. 22 Clinical Application Acne Vulgaris most common skin disorder sebum and epithelial cells clog glands produces whitheads and blackheads (comedones) anaerobic bacteria trigger inflamation (pimple) largely hormonally induced androgens stimulate sebum prodiction treatments include antibiotics, topical creams, birth control pills