1. When printing slides, please use the print handout option and select black and white option.
That way, you will not print black backgrounds and thus save ink!

2. When printing slides, please use the print handout option and select black and white option.
That way, you will not print black backgrounds and thus save ink!

3. 12.1
Chapter 12 The Cell Cycle
12.1 Mitotic cell division results in genetically identical daughter cells
Mitosis alternates with Interphase in the cell cycle
12.3. Not for exam

4. But first some sections of Ch. 6
6.2
But first some sections of Ch. 6
Some paradigms in Biology
1. All organisms are composed of cells
Note the logarithmic scale
2. There is a universal genetic code shared by all organisms and this code transmits information between generations.

5. Electron microscopy Light microscopy 6.3
Capturing sharp images at many different planes  3D
Variations in density
Variations in density ~3D
Electron microscopy
Light microscopy
Adding dyes to label molecules
6.3

6. 6.4. Research Methods: Cell fractionation
The disruption of a cell and separation of its parts by centrifugation at successively higher speeds.

7. Bacteria, Archaea
6.5. A prokaryotic cell – lacking a true nucleus and other membrane-enclosed organelles

8. 6.8.
Animal cell
Eukaryotic cell

9. 6.8.
A plant cell
Eukaryotic cell

10. DNA: Deoxyribonucleic acid
Chromosomes (DNA + proteins)
Nucleic Acid
Nucleotide
Nucleosome
slinky
2 nm

11. Outline What are cell division and eukaryotic chromosomes?
What is the cell cycle?
What is mitosis?
What is meiosis (Ch. 13)?
What are some meiotic errors (Ch. 13)?

12. Functions of cell division:
1. Reproduction (single-celled organism)
2. Growth and development (multi-cellular organisms)
3. Renewal and repair.
12.2
Cells divide with most components equally shared among the daughter cells;
but the DNA on chromosomes divides with exceptional precision!

13. Mitosis
12.4, 12.5
Chromosome duplication and distribution during cell division

14. The cell cycle

15. 12.7a. The mitotic division of an animal cell

16. 12.7b. The mitotic division of an animal cell

17. 12.10. Cytokinesis in animal and plant cells

19. 12.11. Mitosis in a plant cell. Light micrographs showing mitosis in an onion root cell.

20. Example Question
A cell containing 92 chromatids at the start of mitosis would, at its completion, produce cells containing how many chromosomes?
A) 12
B) 23
C) 92
D) 16
E) 46

21. 12.19. Density-dependent inhibition and anchorage dependence of cell division.
Cancer cells do not follow normal signals that regulate the cell cycle. They lack density-dependent inhibition (crowded cells stop dividing) and anchorage-dependence (must be attached to substrate in order to divide) and continue to divide and invade other tissues.

22. Diving cells near the tip of an onion root
Diving cells near the tip of an onion root. Identify a nucleus in each of the major stages of mitosis and describe major events occurring at each stage.

23. Stages in Mitosis

24. Fig
Bacterial cell division
(binary fission)

25. Look at Chapter 12 Review (book p. 244)
12.1 Mitotic cell division results in genetically identical daughter cells
Mitosis alternates with Interphase in the cell cycle
12.3. Not for exam