1. Introduction to Cell Biology Review of a few basics first

2. Always keep the range of scale in mind. Examples: You can not see molecules (even DNA) with a light microscope. A transmission electron micrograph is not useful for looking at whole cells.

3. Differential centrifugation What’s going on in this series of pictures?

4. Be sure to review concepts learned in last year

5. Search for examples of different types of microscopy so you understand what the possibilities are. http://www.olympusmicro.com/galleries/i ndex.html Light microscopes refract visible light passing through a specimen.

6. Phase contrast enhances contrast in unstained cells making it useful for looking a living specimens

7. Electron microscope reveals structure (often called ultrastructure)

8. No cell looks like this

14. Cytoskeletal elements Microtubules – 25 nm dia, hollow tubes Microfilaments – 7 nm dia, intertwined strands Intermediate filaments – 8-12 nm, supercoiled proteins See Table 6.1, pg 113

15. Support, Motility, Regulation

23. Plant cell walls

24. What’s outside of the cell?

25. What is between the cells?

26. Biochemistry Games http://nobelprize.org/educational_games/ Nobel Prize for Chemistry: play the chirality game Nobel Prize for Medicine:play Cell and Its Organelles, “Megacell”