1. Introduction to Basic Therapeutics Module
Dr. Naser Ashraf Tadvi
Module coordinator

4. Objectives
Describe the concept of Module, including objectives, learning contents, teaching and learning methodology, practicals, references, assessment, and all module related matter
Understand computer assisted learning in experimental Pharmacology
Briefly overview the concept of pharmacology

5. Concept of the Module

6. Theme I: Different Therapeutic Modalities
Introduction to different therapeutic modalities.
Non-pharmacological basis of therapy (e.g. physiotherapy, occupational therapy, radiotherapy, counseling & CAM)
Introduction to pharmacotherapeutics

7. Theme II: How body handles drugs (Pharmacokinetics):
Absorption.
Distribution.
Metabolism.
Elimination.
 How drug acts (Pharmacodynamics):
Receptors (affinity, efficacy & potency).
Theory of drug receptors binding.
Signal transduction apparatus.
Therapeutic index and therapeutic window
 Individual variations in drug response (pharmacogenomics)
Introduction to Pharmacogenomics.
Clinical relevance of Pharmacogenomics

8. Theme III: Autonomic Pharmacology & Autocoids
Autonomic nervous system drugs
Adrenergic agonists & antagonists.
Cholinergic agonists & antagonists.
Skeletal muscles relaxants.
Autacoids (histamine, serotonin & prostaglandins)
Histamine and antihistamines
Serotonin and anti–serotonin
Prostaglandins and ergot alkaloids

9. Theme IV: Rational & safe prescription including drug development
Drug therapy during pregnancy & lactation
Drug therapy in the geriatric & pediatric groups.
Adverse drug reaction (ADR).
Principles of toxicology.
Drug interactions
Safe prescribing habits.
Cost effective drug therapy.
Compliance & adherence
Monitoring of drug treatment
National & international drug evaluation & regulation

10. Teaching and learning methods
Lectures: 30
PBL: 4
CD: 5
Seminars: 5
Practicals: 6
Tutorial: 2
Field Visit: 1

11. Practicals All practicals have Computer Assisted Learning
At the end of each practical the students will be evaluated in the last half hour
The quiz for each practical will be of ten marks
MCQs or SEQs related to practical can be asked
There will be no separate mid term practical exam
10 % of these marks will be considered as midterm practical exam marks
Explain here what is computer assisted learning
Stress that students have to be attentive in practicals

12. Assessment
Continuous Assessment %
Final Assessment %

13. Continuous assessment
Mid Module exam
20 %
Multiple choice questions
60 marks
40 MCQs
Short essay questions
40 Marks
05 SEQs
Activities Marks
30 %
Problem Based Learning (PBLs)
160 Marks
04 PBLs
Case Discussion (CDs)
75 Marks
05 CDs
Quiz PBL, CDs, Seminars
04 Quiz
Seminar
100 Marks
01 Seminar
Mid Term Practical Exam
Practical 2,3,4
30 Marks
10% of this

14. Mid module exam (will cover)
Lecture 1 to lecture 15
PBL 1 & PBL 2
CD 1 & CD 2
Seminar 1 & Seminar 2

15. Quizzes (10 marks each) Quiz 1 Quiz 2 Quiz 3 Quiz 4
PBL 1, CD1, Seminar 1
Quiz 2
PBL 2, CD2, Seminar 2
Quiz 3
PBL 3, Seminar 3, CD 3
Quiz 4
PBL 4, Seminar 4, seminar 5, CD4, CD5

16. Final Assessment Final Assessment 40 % Final module examination 30 %
Multiple choice questions
60 marks
60 MCQs
Short essay questions
40 Marks
05 SEQs
Final Practical examination
10 %

17. Attendance 75 % attendance is compulsory for eligibility in exam
PBLs, CDs, quizzes, practical's and Seminars absence will lead to loss of marks in continuous assessment

18. Concept of Pharmacology
Drug therapy involves a great deal more than matching the name of the drug to the name of a disease; it requires knowledge, judgement, skill and wisdom, but above all a sense of responsibility.
Give brief idea

19. Learning resources
Illustrated reviews Pharmacology, Ed. Lippincott. 5th Edition,
Katzung & Trevor’s Basic and Clinical Pharmacology. 12th Edition,
Reference book:
Goodman & Gilman Pharmacological Basis of Therapeutic th Edition

20. At the end of module