1. 1 Yellow Fever Allison Gregg

2. 2 General History thousands of years old originated in Africa brought to the U.S. in the 1500s

3. 3 General History Walter Reed discovered how YF is transmitted-mosquitoes Yellow Fever from yellow color from liver failure

4. 4 General History and Structure Asian countries are habitats for mosquitoes that carry Yellow fever Single stranded RNA Shape: spheroidal

5. 5 How YF is Transmitted 2 transmission methods: –“jungle cycle” –“urban cycle”

6. 6 How YF is Transmitted can only be transmitted through mosquito bites cannot survive outside its vector-the mosquito

7. 7 How YF is Transmitted originally from monkeys becomes permanently fixed in salivary glands of mosquito

8. 8 Who is affected

9. 9 tropical regions of Africa and South America 30,000 deaths each year worldwide estimate of 200,000 cases a year

10. 10 Who is affected epidemics usually affect 20% of the population unvaccinated populations can have death rates above 50%

11. 11 Symptoms incubation period of 3-6 days “acute” phase “toxic” phase

12. 12 Symptoms 15% go into “toxic phase” 50% of “toxic” cause death hard to diagnose disease

13. 13 Vaccine a live-virus vaccine Vaccine must be given every 10 years 95% immunity a week after vaccination

14. 14 http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH 0002341/http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH 0002341/ http://www.who.int/mediacentre/factsheets/fs100 /en/http://www.who.int/mediacentre/factsheets/fs100 /en/ http://www.yellowfever.com.au/vaccine.html http://www.microscopy- uk.org.uk/mag/indexmag.html?http://www.micros copy-uk.org.uk/mag/art98/aedrol.htmlhttp://www.microscopy- uk.org.uk/mag/indexmag.html?http://www.micros copy-uk.org.uk/mag/art98/aedrol.html http://www.cdc.gov/ncidod/dvbid/yellowfever/