1. 1. 4. Ribosome Translation 3. Protein 2. BELL WORK ( Buff Binder – start a new sheet !): Fill in the blanks on the diagram below: DNAmRNA Transcription Nucleus

2. Set up today’s page… Title: Translation Page: 36 Date: 10-23-14 Essential Question: What is translation and what is its purpose?

3. Let’s do some Test Analysis! Use the answer key below to correct your test. 1.C 2.D 3.A 4.A 5.D 6.B 7.A 8.C 9.C 10.D 11.C 12.B 13.D 14.C 15.D 16.C 17.B 18.A 19.D 20.C 21.A 22.B 23.A 24.B 25.B 26.C 27.D 28.C 29.B 30.B

4. Here are the grades… -1 = 97 -2 = 93 -3 = 90 -4 = 87 -5 = 83 -6 = 80 -7 = 77 -8 = 73 -9 = 70 -10 = 67 -11 = 63 -12 = 60 -13 = 57 -14 = 53 -15 = 50 -16 = 47 -17 = 43 -18 = 40 -19 = 37 -20 = 33 -21 = 30 -22 = 27 -23 = 23 -24 = 20 -25 = 17 -26 = 13 -27 = 10 -28 = 7 -29 = 3 -30 = 0

5. Central Dogma Analogy DNA = master copy of building plans mRNA = blueprint for one room of building Protein = actual bricks that make up the building Nucleus = boss’s office Ribosome = job site (where the building is actually built)

6. Translation: decoding of an mRNA message into a polypeptide chain occurs on a ribosome (OUTSIDE the nucleus)

8. Steps: 1.mRNA travels to the ribosome 2.transfer RNA (tRNA) brings amino acids to the ribosome 3.polypeptide (protein) is formed

9. How does tRNA know which amino acid to bring?

10. Codon: three consecutive mRNA bases tRNA looks for the codon that pairs with its anticodon the ribosome takes the amino acid and attaches it to the polypeptide chain Anticodon: three complementary tRNA bases

11. ORDER MATTERS! order of DNA bases  order of RNA bases  order of amino acids  what protein is made tRNA mRNA Amino acids

12. How to use the Codon Chart: 1.Use the left side to find the first letter in the codon 2.Use the top to find the second letter in the codon 3.Use the right side to find the third letter of the codon 4.Go to where ALL three overlap on the chart

14. Did you notice?: The codon “AUG” can specify methionine or serve as the “start” codon for protein synthesis.

15. How to use the Codon Wheel: 1.Begin in the middle with the first letter of the codon 2.Go outward to the second letter in the codon 3.Go outward again to the third letter in the codon.

16. What other codons will tell the ribosome to stop putting amino acids together? What DNA sequences will give you these codes?

17. Let’s do some Test Analysis! Use the answer key below to correct your test. 1.C 2.D 3.A 4.A 5.D 6.B 7.A 8.C 9.C 10.D 11.C 12.B 13.D 14.C 15.D 16.C 17.B 18.A 19.D 20.C 21.A 22.B 23.A 24.B 25.B 26.C 27.D 28.C 29.B 30.B

18. Here are the grades… -1 = 97 -2 = 93 -3 = 90 -4 = 87 -5 = 83 -6 = 80 -7 = 77 -8 = 73 -9 = 70 -10 = 67 -11 = 63 -12 = 60 -13 = 57 -14 = 53 -15 = 50 -16 = 47 -17 = 43 -18 = 40 -19 = 37 -20 = 33 -21 = 30 -22 = 27 -23 = 23 -24 = 20 -25 = 17 -26 = 13 -27 = 10 -28 = 7 -29 = 3 -30 = 0

19. Complete your Test Analysis sheet. It should be taped on page 37. Color INCORRECT questions red. Color CORRECT questions green. Write your Important Vocabulary for each standard and use the words in a sentence.