1. Citow Review Pathology 8/2/13

2. High levels of alpha-fetoprotein are associated with a)Endodermal sinus tumors b)Choriocarcinomas c)Germinomas d)Pineoblastomas e)Teratomas

3. High levels of alpha-fetoprotein are associated with a)Endodermal sinus tumors b)Choriocarcinomas c)Germinomas d)Pineoblastomas e)Teratomas

4. High levels of human chorionic gonadotropin are seen in a)Choriocarcinoma b)Embyronal carcinoma c)Endodermal sinus tumor d)Germinoma e)Teratoma

5. High levels of human chorionic gonadotropin are seen in a)Choriocarcinoma b)Embyronal carcinoma c)Endodermal sinus tumor d)Germinoma e)Teratoma

7. Viral inclusions seen in herpes encephalitis are a)Basophilic b)Called Cowdry B bodies c)Found in neurons only d)Intranuclear e)Only evident several weeks after infection

8. Viral inclusions seen in herpes encephalitis are a)Basophilic b)Called Cowdry B bodies c)Found in neurons only d)Intranuclear e)Only evident several weeks after infection

9. Inclusion Bodies IntracytoplasmicIntranuclear NF tangles Pick bodies Lewy bodies Negri bodies Lafora bodies Bunina bodies Cowdry A Cowdry B Marinesco bodies (ALS) (myoclonic epilepsy) (rabies) (Parkinsons, Lewy body dis) (Pick’s disease) (Alzheimer’s) (CMV, Herpes, SSPE) (Polio)

10. Cowdry A Inclusions

11. Each of the following is characteristic of Wilson’s disease except a)Alzheimer’s type II astrocytes b)Atrophy & brownish discoloration of globus pallidus & putamen c)Autosomal dominant d)Decreased serum ceruloplasmin e)Decreased serum copper

12. Each of the following is characteristic of Wilson’s disease except a)Alzheimer’s type II astrocytes b)Atrophy & brownish discoloration of globus pallidus & putamen c)Autosomal dominant d)Decreased serum ceruloplasmin e)Decreased serum copper

13. Wilson’s Disease Mutation in ATP7B gene (ch. 13) – ATPase transporter that incorporates copper into ceruloplasmin Low ceruloplasmin, low copper Alzheimer type II astrocytes Abnormal LFTs MRI: hyperintense BG on T2 Keiser Fleischer rings Renal tubular acidosis Cardiomyopathy