1. Due Thursday, October 8th Hardy Weinberg Analysis

2. Case 1 Analysis In your lab book, compare your small population data with your large population. Press F9 a few times to simulate a few different trials. Record all of your observations Describe what you are seeing (qualitative) in your computer model. What forces could be acting upon this? Is it truly in H-W equilibrium? Why or why not?

3. Case 2 Analysis- Natural Selection In your lab book, compare your data for Natural Selection after 5 generations with your computer model with 1000 individuals after 5 generations. Press F9 a few times to simulate a few different trials. Record all of your observations Describe your comparison.

4. Case 3 Analysis-Independent Investigation Choose another condition to model. Examples include: Gene Flow Mutations (the dominant becomes recessive) Heterozygote Advantage Non-random mating Press F9 a few times to simulate a few different trials. Record all of your observations

5. Case 3: Independent Investigation You will complete a full investigation and create a mini- poster. 1. Determine your question (non-random mating, gene flow, mutation). 2. Record your review of literature (text book). 3. Formulate your hypothesis. 4. Record your procedure. This includes: 1. Your scenario for the change 2. Your formula that models that change. 5. Analyze your data 6. Write a brief conclusion.

6. Example scenario… If I were to use natural selection: There is a population of bakerbugs. In Bakerbugs, following the proper rules of “simon says” is dominant (A) and following the new weird rules of “Nibbly Bibble” is recessive (a). All of a sudden, the environment changes. Those who are homozygous recessive and those who are heterozygous survive, but those who are homozygous dominant only survive 25% of the time. You need to express this in a formula in order to model it through the generations.

7. And formula Original formula: A alleles = AA*2+AB B alleles = BB*2+AB New Formula A alleles = (AA*2*.25)+AB (“.25 represents the 25% that survived) B Alleles stays the same Tips- if your formula gives you alleles in a decimal, reformat the cells to round them to a whole number; you can’t have part of an allele in a population.