1. ProStar 500 CVM P. van Poppel – Field Support Specialist October 2009

2. Overview Introduction to CVM Options Usage Configurations Operation and Control Front panel Software Problems

3. Column Valve Module (CVM) 1.Column selector 2.Solvent selector 3.Diverter and Fraction collector 4.Column heater 5.Manual Injector

4. Column Valve modules Options Holds up to 4 Automated valves Hold up to 4 manual valves in front panels (any kind) One or two independent column heater blocks Vapor sensor Holds 6 analytical or 2 prep (2 in) columns

5. Solvent selector

6. Column selector

7. System with ternary pump

8. Diverter and Fraction collector valves

9. Control and Operation Front panel control Configure new valves Set all valve positions Set column temperature Set vapor response Divide valves between two different instruments CANNOT TIME PROGRAM VALVE POSITIONS FROM FRONT PANEL

10. Control and Operation BCD control Time program valves from an external computer via contact closures BCD always built in Computer control basics RS 422/485 serial communications –This is different than the ProStar communications line and cannot share the same line Independent of Galaxie - works with any other software Runs with Galaxie through AutoLink Computer control capabilities Time program valve movements through methods Manually control valve movements through the computer Control all other front panel operations Preserve solvent compatibility during operations

11. Software control of the CVM

12. Prevents solvent incompatibility

13. Checking solvent compatibility

14. Documentation of columns and solvents

15. Problems Valve Status problem Valve leaks Communications problems Heater does not heat