1. From Biofuels and Beyond Inspired Science to Deliver Sustainable Solutions for a Growing World Joel Velasco April 2014

2. 2 Copyright © 2012 Amyris, Inc. All rights reserved. This presentation and oral statements accompanying this presentation contain forward-looking statements, and any statements other than statements of historical facts could be deemed to be forward-looking statements. These forward-looking statements include, among other things, sizes of markets that may be addressed by Amyris’s current and potential products, Amyris’s expected product pipeline, sales volumes and average selling prices, production volumes and costs and associated product launch timing expectations, operation of production facilities, commercial relationships, and financial results, that involve risks and uncertainties. These statements and other forward-looking statements that may be provided in the presentation and/or oral statements accompanying it are based on management’s estimates and current expectations and actual results and future events may differ materially due to changes in Amyris’s business and various risks and uncertainties, including those associated with any delays or failures in development, production and commercialization of products, liquidity and ability to fund capital expenditures, Amyris’s reliance on third parties to achieve its goals, and other risks detailed in the “Risk Factors” section of Amyris’s quarterly report on Form 10-K filed on April 2, 2014. Amyris disclaims any obligation to update information contained in these forward-looking statements whether as a result of new information, future events, or otherwise. Cautionary Note re: Forward Looking Statements

3. 3 Copyright © 2012 Amyris, Inc. All rights reserved. 3 The Renewable Fuel Standard (RFS2)

4. 4 Copyright © 2012 Amyris, Inc. All rights reserved. RFS2 as Imagined Source: EISA of 2008, U.S. Environmental Protection Agency (RFS-2) Final Rule.

5. 5 Copyright © 2012 Amyris, Inc. All rights reserved. RFS2 as Expected Source: EISA of 2008, U.S. Environmental Protection Agency (RFS-2) Final Rule. Assuming current EPA approach, RFS mandated volumes only increase to the extend total gasoline consumption increases… Blend Wall (10% Gasoline Demand)

6. 6 Copyright © 2012 Amyris, Inc. All rights reserved. EIA’s Gasoline and Diesel Consumption Outlook US motor gasoline and diesel consumption (million barrels per day) AEO2013 AEO2007 AEO2010 Gasoline AEO2007 AEO2010 AEO2013 Diesel Source: EIA, Annual Energy Outlook 2007, Annual Energy Outlook 2010, Annual Energy Outlook 2013

7. 7 Copyright © 2012 Amyris, Inc. All rights reserved. 7 From Biofuels and Beyond

8. 8 Copyright © 2012 Amyris, Inc. All rights reserved. Amyris: The Industrial Synthetic Biology Company Founded in 2003 by post-doctoral fellows from the University of California, Berkeley. Headquartered in the San Francisco Bay Area and with operations in Brazil. 390 full-time employees, of which one-third are PhDs. Backed by leading investors and strong partnerships with global brands. Best-in-Class Tech Scaled Manufacturing No Compromise ® Products AMYRIS PLANT IN BRAZIL AMYRIS HQ IN CALIFORNIA

9. 9 Copyright © 2012 Amyris, Inc. All rights reserved. Isoprene (C5) F&F Molecules FARNESENE (C15) Living Factories Delivering Better Products Diesel Jet Fuel Fuels Base Oils Finished Lubricants Lubricants Polymers Solvents and Fluids Performance Materials Cosmetic Emollients Flavor & Fragrances Consumer Care Amyris engineers living factories and produces renewable products

10. 10 Copyright © 2012 Amyris, Inc. All rights reserved. From Curing Malaria to Better Fuels and Chemicals Delivering sustainable growth for the worlds leading brands BIOLDING investment LEADING INVESTORS

11. 11 Copyright © 2012 Amyris, Inc. All rights reserved. Significant Addressable Markets Diverse Production Portfolio Today with Improving Profitability

12. 12 Copyright © 2012 Amyris, Inc. All rights reserved. Amyris Business Model: Partner-funded product collaboration pipeline, long-term annuity from sales, and industry leading gross margin Strategic & Capability Building Partners Strategic & Capability Building Partners COLLABORATIONS RENEWABLE PRODUCTS COLLABORATION INFLOWS Expect to continue at $60M to $70M annually PRODUCTION & SALES Expect to double year-on year during the next few years PROVIDES CASH FOR R&D OpEx and CapEx Investments in high-value Farnesene Industry leading cash gross margin Over 15 new molecules under contract with 1 to 3 new product launch per year DRIVER OF Revenue Growth Earnings through Long-Term Supply Operations OpEx and CapEx Customers

13. 13 Copyright © 2012 Amyris, Inc. All rights reserved. Developed high-throughput strain engineering system to code and screen over 100,000 yeast strains per month at 95% lower cost. Generated over 600,000 unique farnesene strains in last year, surpassing 3 million strains. Tested over 5,000 unique strains in actual fermentation to date and now predict 200,000 liter fermentation performance from 2 liter scale tests. Reduced time to target isoprenoid molecule from years to months, with thousands of molecules to be accessed. Developed high-throughput strain engineering system to code and screen over 100,000 yeast strains per month at 95% lower cost. Generated over 600,000 unique farnesene strains in last year, surpassing 3 million strains. Tested over 5,000 unique strains in actual fermentation to date and now predict 200,000 liter fermentation performance from 2 liter scale tests. Reduced time to target isoprenoid molecule from years to months, with thousands of molecules to be accessed. Amyris Synthetic Biology Technology Platform The Science of Genentech with the Engineering of Intel Design based on Learnings Build: Robotics & Automation Test: 100,000 strains/month

14. 14 Copyright © 2012 Amyris, Inc. All rights reserved. The Leading Innovator in Industrial Biotech

15. 15 Copyright © 2012 Amyris, Inc. All rights reserved. Summary TECHNOLOGY Leading technology platform capable of making 50,000 molecules. Engineer yeast to convert sugar into renewable hydrocarbons. MANUFACTURING Access to lowest cost feedstock (sugarcane). Lowest carbon footprint. First plant operating with capital light approach. PRODUCTS Anti-malarial drug precursor (no profit). No Compromise ® fuels and specialty chemicals, with initial sales ongoing. INTEGRATED RENEWABLE PRODUCTS COMPANY

16. 16 Copyright © 2012 Amyris, Inc. All rights reserved. For Further Reading Visit our website at investors.amyris.com

18. 18 Copyright © 2012 Amyris, Inc. All rights reserved.

19. 19 Copyright © 2012 Amyris, Inc. All rights reserved. 2004 Amyris, a “virtual company” licenses back Synthetic Biology patent portfolio. 2005 Amyris opens with a $15M of a five-year grant from the Bill and Melinda Gates Foundation to develop anti-malarials with Synthetic Biology platform. 2006 Amyris takes venture capital to apply SynBio platform to hydrocarbon fuels & chemicals. 2007 John Melo, former president of BP’s US Fuels division 2007 Amyris team makes “first drops” of renewable diesel in the lab 2008 key technical milestones in anti-malarial drug production –partners with Sanofi-Aventis to scale-up & commercialize anti-malarial drug 2008 Amyris opens Pilot Plant for fuel in Emeryville; “first gallons” of diesel 2009 Successful Artemisinin technology transfer to Sanofi-Aventis 2009 Amyris produces “first barrels” of diesel 2010 Partnership with Total 2010 IPO (AMRS) 2011 Begin sales of Diesel and Squalane 2012 Amyris produces 2 Million liters of Diesel and Squalane 2013 Launch Artemisinin 70-120 million malaria cures (Sanofi) A Brief History of Amyris