1. Why a CPCRN? CDC Expectations Katherine M. Wilson, PhD, MPH CPCRN Technical Monitor Division of Cancer Prevention and Control CDC

2. Original intent for CPCRN To create an infrastructure that could be active in applying relevant research to local cancer prevention and control needs, while working across academic centers to maximize resources and tap synergistic forces. Cover the continuum of cancer research, from prevention to diagnosis to treatment to survivorship or end-of-life care.

3. Underlying premises The Guide to Community Preventive Services (CG) is used to influence the selection of intervention research. A mix of the types of research should be achieved so that the majority of the research rests on the “delivery” side of the continuum.

4. Discovery Development Delivery Policy Diffusion Diffusion & Dissem. Research Dissemination Knowledge Synthesis Implementation Replication Research Nearly sufficient Evidence Community Guide- Evaluated Recommended but needs testing in new pops/settings Recommended but needs disseminating in original pops/settings Recommended but needs program evaluation tools Program Services (e.g., NBCCEDP; CCC)

5. A Critical Juncture for CCC Programs: Current Challenges Completing the plan Setting priorities Resourcing the plan Sustaining the partnership commitment Establishing a system of accountability Monitoring progress Evaluating outcomes Implementation at the community level

6. How? Community-based participatory research 3 types of community - Traditional CBPR with local network. - CPCRN – 8 Centers & CC - Grey area where community includes affiliate members, other organizations or groups, such as ACS, CDD, NBCCEDP, CCC, other programs at CDC, plus selected members of local networks,.

7. CPCRN Challenges Balancing the activities in each type of community to reach outputs. Balancing resources for infrastructure with need for pilot studies.

8. Priority Research Areas Effectiveness of community interventions for which there is nearly sufficient evidence for a CG recommendation. Effective replication of CG-recommended interventions. Effective dissemination of CG- recommended interventions with health depts. and other cancer control partners.

9. Priority Research Areas - 2 Evaluation of CG-recommended community interventions already implemented by state health depts. and others. Evaluation of CG-recommended community interventions already implemented by state health depts. and others, but which are not recommended by the Guide because of insufficient evidence.

10. What can CPCRN expect from CDC? Commitment to funding infrastructure. A few SIPs. Introduction to our partners, networks, and other contacts useful to achieving outputs. Willingness to listen and to problem-solve.

11. Discussion NCI & CDC expectations of the CPCRN CPCRN expectations of the NCI & CDC

12. CPCRN Network Centers Coordinating Center CDC NCI Affiliate members? Other organizations ? INPUTS If we have this to draw on... Infrastructure activities ACTIVITIES We can do this.. OUTPUTS Which will produce this... 1. Strong processes for networking, coordinating, cooperating, and collaborating are in place OUTCOMES Which will lead to these... Network is aware of factors influencing intervention selection in the field Network is able to respond to program requests And then these... Marketing and promotion of efforts Replication research in multiple sites and settings Program Evaluation Intervention research related to Guide recs Dissemination research in multiple sites and settings 2. Best messages and channels for reaching target audiences are known and employed 3. State plans for improving or continuing to improve cancer prevention and control 4. Change in number and completeness of Guide recommendations 5. Standard replication process developed 6. Standard dissemination process developed Field knows which intervention strategies are recommended by the Guide Field is able -to match and select intervention strategy appropriate to situation -to replicate interventions -to disseminate interventions Field implements evidence-based interventions for cancer-related topics which have Guide recommendations Increased informed decision making for cancer screening Increased use of effective cancer screening tests Reduced consumption of tobacco products Increased dietary change & physical activity Increased sun safety

13. Strong processes for networking, coordinating, cooperating, and collaborating are in place. OUTPUT #1 Which will produce this in 5 years… Research portfolio diversity. Diversity of funding sources. Collaborative publications. Collaborative research awards and type. Minority researchers.

14. OUTPUT #2 Which will produce this in 5 years… Increase in evidence for intervention categories currently having insufficient evidence, where a few additional studies could lead to a CG recommendation. Increase in evidence for intervention strategies where recommendation exists, but where gaps remain. Change in number and completeness of Guide recommendations.

15. OUTPUT #3 Which will produce this in 5 years… Reports, plans, or policies generated in collaboration with state-level programs. Participation in CCC program Leadership Institute. Extramurally funded evaluation studies of the effectiveness of a CG-recommend community intervention category conducted collaboratively. Collaborative evaluation of current interventions or program materials which are not evidenced-based or evidence-informed. Approaches for improving or continuing to improve cancer prevention and control.

16. OUTPUT #4 Which will produce this in 5 years… CPCRN interventions included in PLANET RTIPS. CPCRN (local/Network) research presented. CPCRN (local/Network) research published. Field has capacity to choose, deliver, and evaluate CG related interventions. Best messages and channels for reaching target audiences are known and employed.

17. OUTPUT #5 Which will produce this in 5 years… 1. Measures. 2. Methods. 3. Indicators of success defined. Standard replication process developed.

18. OUTPUT #6 Which will produce this in 5 years… 1. Measures. 2. Methods. 3. Indicators of success defined. Standard dissemination process developed.

19. Questions for small groups What is your reaction to the outputs and products suggested for 5 years? What are your recommendations? What other considerations are important to achieving these outputs in 5 years?