1. Affirm TM Anti- Aging Workstation Wrinkles Facial Rejuvenation Surgical Scars Acne Scars Stretch Marks Skin Tightening

2. NEXT Depth of Penetration by Wavelength (not to scale) 1064 Nd:YAG 810 Diode 755 Alexandrite 1540 Er:Glass 1550 Fiber Laser 694 Ruby 585 – 595 Pulse Dye 1440 Nd:YAG 2940 Er:YAG Micro- dermabrasion 1320 Nd:YAG Intense Pulsed Light

3. NEXT CO 2 Er:YAG 1064nm 1320nm IPL 21 st century Early 1980s PDL Non-ablative Affirm with CAP Technology Affirm with CAP Technology Ablative History of Skin Rejuvenation

4. NEXT How the Affirm Technology Works Aged Skin Rejuvenated SkinFine lines, wrinkles, etc.2 nd laser pulse Skin Tightening1 st laser pulse

5. NEXT Cold air cooling system to -4 C Cools before, during & after Tx Increases patient comfort Easy to use delivery system No disposable costs or window change required No skin reaction as opposed to Cryogen spray …“No serious aesthetic practice should be without one.” AT&T Choice Award 2005 Affirm and Smart Cool: The Ultimate Package

6. NEXT Cross section of 50 year old skin Cross section of 18 year old skin Epidermis Photo aged skin ~300 µm (dermis) Healthy skin (dermis) Epidermis Healthy skin (dermis) Photo aged skin: minimal - none Affirm Advantage: Target Tx Approach

7. NEXT Areas Treated Immediate Post-TX Transient redness and swelling Intermediate Erythema that lasts between 2-24hours Tan or dusky appearance of skin in some subjects Starts 1-3 days post treatment; last 1-2 weeks Affirm Treatment

8. NEXT Micro-thermal Rejuvenation Baseline 1 Month Post 3 Tx Courtesy Dr. R. Weiss Affirm Clinical Proof 3.0 J/cm²

9. NEXT Mature Scar on the forearm Baseline 1 month Post 6 Tx Courtesy Dr. R. Weiss Affirm Clinical Proof 3.0 J/cm²

10. NEXT Scar Baseline 1 month Post 2 Tx Courtesy Dr. R. Weiss Affirm Clinical Proof 3.0 J/cm²

11. NEXT Stretch Marks Baseline 1 Month Post 2 Tx Courtesy Dr. M. Mikhail Affirm Clinical Proof 3.0 J/cm²

12. NEXT Stretch Marks Baseline 1 Month Post 2 Tx Courtesy Dr. R. Weiss Affirm Clinical Proof 3.0 J/cm²

13. NEXT Peri-oral Wrinkle Treatment 6 months Post 5 Tx Baseline Courtesy Dr. R. Weiss Affirm Clinical Proof 3.0 J/cm²

14. NEXT Skin Tightening Skin Laxity: Improvement of lines and skin texture In mid treatment – Post 1 month post previous Tx Courtesy of E. Tanghetti, MD

15. NEXT Acne Scarring Baseline 1 mo post 2 treatments

16. NEXT Peri-Ocular Wrinkles Baseline 1 month post 3 treatments

17. NEXT Acne Scarring Baseline 1 month post 2 treatments

18. NEXT Acne Scarring Baseline 1 month post 2 treatments

19. NEXT Wrinkle Reduction 1 month post 5 treatments Baseline

20. NEXT Before and After BEFOREAfter 6 treatments Courtesy of Heather Endicott, NP Dermatology/Cosmetic Laser Associates of La Jolla, Inc.

21. NEXT Q+A THANK YOU for your attention!!!!